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Vol 18, No 1 (2021)

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Authors in this issue:

Abdurachman Sukadi, Adaleta Softić, Adisa Chikha, Adisa Pilavdžić, Adnan Šerak, Adriel Benedict, Agung Putra, Ahmad Hemaidi, Aida Drljević, Alberto Galeotti, Alberto Rigon, Alberto Schiavo, Alden Begić, Alessandro Manelli, Alessandro Stasi, Alessandro Tomarchio, Alexander Roshal, Ali Pourhabib, Ali-asghar Jesmi, Alija Uzunović, Alma Trnačević, Amarildo Smakaj, Amela Bećirović, Amer Iglica, Amer Mujkanović, Amila Jaganjac, Amra Nadarević Vodenčarević, Amra Serak, Ana Kvolik Pavić, Anatolii Onishchenko, Andrea Facchini, Andrea Pasquino, Anida Divanović, Anis Cerovac, Anis Međedović, Anja Divković, Annamaria dell’Unto, Anton Tkachenko, Antonella Abate, Antonella Cotoia, Antonio Catricalà, Antonio Cicione, Attilio Basile, Auro Caraffa, Avdo Voloder, Azra Bureković, Azra Sadiković, Beatriz Lozano-Hernanz, Besim Prnjavorac, Carla Vitiello, Carlo Salomone, Carolina Giannace, Christian Carulli, Corrado Filippo Castrioto, Corrado Pinelli, Cristina De Dominicis, Cristina Ibáñez-Vicente, Cristina Lopez Palacios, Cristina Razzano, Damiano Longo, Damir Čelik, Daniel Vicente Velarde-Garrido, Daniele Caviglia, Dariush Ghargozloo, David Gómez Garrido, Dewi Masyithah Darlan, Dharma Lindarto, Diana Amellya, Dmitry Popkov, Dogac Karaguven, Domenico De Mauro, Domenico Visceglie, Dubravko Habek, Dženana Hrustemović, Đemil Omerović, Edin Begić, Edina Lazović Salčin, Edina Muratović, Edina Tanović, Egemen Turhan, Elias Liolis, Elisa Troiano, Elma Ćatović-Baralija, Elvira Đozo, Elyas Hosseinzadeh-younesi, Emina Karahmet, Emina Rovčanin, Emir Trnačević, Enida Nevačinović, Enio De Cruto, Enrico Maria Bonura, Enrique Sanchez-Munoz, Enzo Pagliarulo, Erdi Özdemir, Erial Bahar, Ermina Iljazović, Esma Karahmet, Fabio Cosseddu, Fatima Hukić, Fatima Numanović, Federico Cartei, Federico Sacchetti, Fikret Veljović, Filla Reviyani Suryaningrat, Francesca Negro, Francesca Romana Barbieri, Francesca Romana Rossetti, Francesco Arienzo, Francesco Giron, Francesco Ippolito, Francesco Liuzza, Francesco Luceri, Francesco Manfreda, Francesk Mulita, Gabriele Falzarano, Gazi Huri, Georgios Karpetas, Georgy Chibirov, Giacomo Peri, Gianluca Ciolli, Gianpaolo Chitoni, Gianpaolo Santini, Giulio Maccauro, Giuseppe M. Peretti, Giuseppe Pica, Giuseppe Rinonapoli, Giuseppe Rollo, Giuseppe Rovere, Giuseppe Sarti, Giuseppe Talesa, Gorana Ahmetović-Karić, Guido Rocca, Hadžan Konjo, Hana Omerović, Haris Čampara, Haris Nikšić, Heda Melinda Nataprawira, Hemma Yulfi, Hurija Džudžević Čančar, Indri Seta Septadina, Ioannis Maroulis, Irfan Prnjavorac, Ismar Rašić, Jacopo Conteduca, Jasmina Redžepagić, Jasmina Smajlović, Juan Antonio Herrera-Molpeceres, Kemal Durić, Kemas Abdul Mutholib Luthfi, Lawrence Camarda, Lejla Begić, Lejla Džananović, Lejla Kamerić, Lejla Prnjavorac, Lejla Šaranović-Čečo, Leonardo Stramazzo, Leticia Alarma-Barcia, Levan Tchabashvili, Lidia De Falco, Lorenzo Bagalà, Lorenzo Scialpi, Luca Giannini, Luca Tarotto, Luciano Mastronardi, Lucio Dell’Atti, Luigi Meccariello, Mahira Durić, Mahyudin Mahyudin, Mairbek Pliev, Maja Konrad Čustović, Marco Gesi, Marco Spoliti, Maria Cristina Varone, Mario Cherubino, Mario Ronga, Martina Cesari, Martina Di Meglio, Massimo Innocenti, Matteo Innocenti, Mattia Fortina, Mauro Ballerini, Meliha Halilbašić, Merima Gegić, Michael Mazzacane, Michail Vailas, Michele Bisaccia, Michele Losco, Michele Romeo, Michele Santodirocco, Miguel Carrato-Gomez, Mirsad Babić, Mirsad Dorić, Mostafa Rad, Mufid Burgić, Muhammad Fakhrur Rozi, Nadža Zubčević, Nedim Begić, Nerma Čustović, Nermin Salkić, Nermina Babić, Nesina Avdagić, Nicola Bianchi, Nicola Mondanell, Nicola Mondanelli, Nicolò Nuvoli, Nijaz Tihić, Nina Čamdžić, Nusret Butković, Oksana Nakonechna, Paolo Ceccarini, Pasquale Quassone, Pasquale Sessa, Paula Romera-Olivera, Pierlugi Cuomo, Piero Ronchi, Pietro Aiuto, Pietro Cirfeda, Predrag Grubor, Raffaele Franzese, Rahmat Budi Kuswiyanto, Redžo Čaušević, Renata Beck, Reuf Karabeg, Riccardo Maria Lanzetti, Roberta Ghezzi, Roberto Buzzi, Rocco Erasmo, Rodolfo Capanna, Rodolfo Corinaldesi, Rosario Petruccelli, Rosita Juwita Sembiring, Sabaheta Hasić, Salvatore Di Giacinto, Salvatore Lucchesi, Sandra Janežič, Sanela Salihagić, Selma Kovčić Hadžiabdić, Silvio Chiossi, Simona Tiburzi, Slavica Kvolik, Sri Endah Rahayuningsih, Stefano Giannotti, Stefano Manno, Suada Kuskunović-Vlahovljak, Svjetlana Radović, Tamer Bego, Taufik Sungkar, Tengku Siti Hajar Haryuna, Tetyana Chumachenko, Umberto Ripani, Urška Dermota, Vahid Jusufović, Valentina Gianpaola Marini, Valentina Li Causi, Valentina Russi, Valerio Arceri, Vanda Zovko Omeragić, Vanna Bottai, Vedran Zubčić, Victor Trivino Sanchez-Mayoral, Vincenzo Caiaffa, Vitaliano F. Muzii, Vittorio Nappi, Vlora Podvorica, Wibi Riawan, Wondi De Marchi, Yevgen Posokhov, Yoyos Dias Ismiarto, Yunilda Andriyani, Zinaida Karasalihović, Zineta Delibegović, Zlatan Zvizdić, Zohreh Mohammadzade-tabrizi,

Published: 09.10.2020.

Contents

09.10.2020. Review paper Biochemistry
Balneogynaecology in the 21st century: increasingly recommended primary and complementary treatment of chronic gynaecological diseases

Balneo-gynaecological treatment methods include external bath hydrotherapy, sedentary baths and topical dressings/cataplasm, and internal (intravaginal or intrarectal use of peloids and mineral water). Hyperosmolar thermal spas have been very popular in the treatment of infertility due to the improvement of symptoms of chronic pelvic pain, endometr...

By DUBRAVKO HABEK, ANIS CEROVAC, LEJLA KAMERIĆ, ENIDA NEVAČINOVIĆ, ADNAN ŠERAK

09.10.2020. Review paper Biochemistry
The importance of plasma ferritin values in blood donors for the evaluation of body iron store in a five-month period

Aim To present haemoglobin and ferritin parameters in donors to highlight the importance of serum ferritin testing for the purpose of evaluating iron depots in order to make recommendations for preserving a population of blood donors.Method A prospective study was conducted on 80 blood donors divided in two groups: group I (regular donors, n =40) a...

By ELMA ĆATOVIĆ-BARALIJA, GORANA AHMETOVIĆ-KARIĆ, SABAHETA HASIĆ, NESINA AVDAGIĆ, NERMINA BABIĆ

09.10.2020. Review paper Biochemistry
Clinical use of an analysis of oxidative stress and IL-6 as the promoters of diabetic polyneuropathy

Aim To investigate interleukin 6 (IL-6) values depending on duration of diabetes mellitus (DM) and evaluate possible correlationwith diabetic polyneuropathy.Methods The research study included 90 patients with DM divided into three groups (30 patients each) according to the durationof DM: group A – patients who had DM for less than 10 years, ...

By EMINA KARAHMET, BESIM PRNJAVORAC, TAMER BEGO, ADALETA SOFTIĆ, LEJLA BEGIĆ, EDIN BEGIĆ, ESMA KARAHMET, LEJLA PRNJAVORAC, IRFAN PRNJAVORAC

09.10.2020. Review paper Biochemistry
Lived experiences of patients with COVID-19 infection: a phenomenology study

Aim To describe experiences of patients with COVID-19 infection.Methods This qualitative research was conducted using a phenomenological approach, and participants were selected via purposive sampling. In total, 14 patients with COVID-19 were selected (nine women and five men) aged 20-60 years. Data were collected via in-depth interviews with open ...

By ALI-ASGHAR JESMI, ZOHREH MOHAMMADZADE-TABRIZI, MOSTAFA RAD, ELYAS HOSSEINZADEH-YOUNESI, ALI POURHABIB

09.10.2020. Review paper Biochemistry
Comparison of analgesic efficacy of acetaminophen monotherapy versus acetaminophen combinations with either pethidine or parecoxib in patients undergoing laparoscopic cholecystectomy: a randomized prospective study

Aim To investigate analgesic effect of three different regimens of combination of analgesics administered to patients undergoing laparoscopic cholecystectomy.Methods Patients undergoing laparoscopic cholecystectomy were randomly allocated to one of three groups on admission, depending of a prescribed post-operative analgesic regimen. Patients alloc...

By FRANCESK MULITA, GEORGIOS KARPETAS, ELIAS LIOLIS, MICHAIL VAILAS, LEVAN TCHABASHVILI, IOANNIS MAROULIS

09.10.2020. Review paper Biochemistry
Left to right shunt congenital heart disease as a risk factor of recurrent pneumonia in under five-year-old children: a single centre experience in Bandung Indonesia

Aim Children with congenital heart diseases are at the greater risk of respiratory tract infection such as pneumonia. Recurrent pneumonia is one of the most major challenge for paediatric physicians. The aim of this study is to investigate risk factors of congenital heart diseases to recurrent pneumonia children.Methods This was a retrospective stu...

By SRI ENDAH RAHAYUNINGSIH, RAHMAT BUDI KUSWIYANTO, FILLA REVIYANI SURYANINGRAT, HEDA MELINDA NATAPRAWIRA, ABDURACHMAN SUKADI

09.12.2020. Review paper Biochemistry
Characterization and clonal representation of MRSA strains in Tuzla Canton, Bosnia and Herzegovina, from 2009 to 2017

Aim To characterize methicillin-resistant S. aureus (MRSA) strains phenotypically and genotypically and to determine their clonal affiliation, representation and antibiotic resistance profile.Methods A total of 62 randomly selected MRSA isolates of different clinical samples collected from 2009 to 2017 were phenotypically and genotypically analysed...

By FATIMA NUMANOVIĆ, URŠKA DERMOTA, JASMINA SMAJLOVIĆ, SANDRA JANEŽIČ, NIJAZ TIHIĆ, ZINETA DELIBEGOVIĆ, AMELA BEĆIROVIĆ, EDINA MURATOVIĆ, MERIMA GEGIĆ

09.10.2020. Review paper Biochemistry
Efficacy and safety of three plant extracts based formulations of vagitories in the treatment of vaginitis: a randomized controlled trial

Aim There are more and more herbal preparations that are used for the purpose of treatment and improvement of the clinical manifestation of vaginitis not only by patients themselves, but also by healthcare professionals. Plant species, St. John’s wort, chamomile, calendula, yarrow, shepherd’s purse and tea tree oil are all well known fo...

By KEMAL DURIĆ, SELMA KOVČIĆ HADŽIABDIĆ, MAHIRA DURIĆ, HARIS NIKŠIĆ, ALIJA UZUNOVIĆ, HURIJA DŽUDŽEVIĆ ČANČAR

09.10.2020. Review paper Biochemistry
Prevalence of Cryptosporidium spp. and Blastocystis hominis in faecal samples among diarrheic HIV patients in Medan, Indonesia

Aim To investigate the prevalence of Cryptosporidium sp. and B. hominis among human immunodeficiency virus (HIV) positive patients in two different outpatient clinics, Haji Adam Malik General Hospital and Primary Care Centre of Padang Bulan, Medan, Indonesia, between two interval periods.Method Cryptosporidium spp. microscopic examination, as well ...

By HEMMA YULFI, MUHAMMAD FAKHRUR ROZI, YUNILDA ANDRIYANI, DEWI MASYITHAH DARLAN

09.10.2020. Review paper Biochemistry
Anti-fibrotic effect of intravenous umbilical cord-derived mesenchymal stem cells (UC-MSCs) injection in experimental rats induced liver fibrosis

Aim To investigate the effect of umbilical cord-derived mesenchymal stem cells (UC-MSCs) administration among liverfibrosis experimental rat model via the regulation of angiotensin II type 1 receptor (AT1R) and platelet-derived growth factor-β (PDGF-β) due to their therapeutic potential to replace liver transplantation for advanced liver ...

By TAUFIK SUNGKAR, AGUNG PUTRA, DHARMA LINDARTO, ROSITA JUWITA SEMBIRING

09.10.2020. Review paper Biochemistry
Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C

Aim To assess concordance of eight frequently used serology-based scoring indices for liver fibrosis and cirrhosis with transient elastography (TE) in chronic hepatitis C (CHC) patients in order to determine serum indices with the highest concordance and clinical usability in clinical practice.Methods In this prospective study, 63 CHC patients were...

By EMIR TRNAČEVIĆ, NERMIN SALKIĆ, ALMA TRNAČEVIĆ, ANJA DIVKOVIĆ, FATIMA HUKIĆ, NUSRET BUTKOVIĆ, AMRA SERAK, AMER MUJKANOVIĆ

09.10.2020. Review paper Biochemistry
An epidemiological study of neuroendocrine tumours at tertiary hospitals in Bosnia and Herzegovina

Aim Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumours with varying clinical expression and behaviour. Because of indolent behaviour of NENs, reviewing and evaluation of epidemiological characteristics is a challenge. The aim of this study was to assess prevalence of NENs at tertiary hospitals considering age, gender, location, an...

By MAJA KONRAD ČUSTOVIĆ, ERMINA ILJAZOVIĆ, AZRA SADIKOVIĆ, ZINAIDA KARASALIHOVIĆ

09.10.2020. Review paper Biochemistry
Appropriateness of colonoscopy at a tertiary care centre – are we overdoing gastrointestinal endoscopy?

Aim To evaluate the pattern of indications and a spectrum of colonic pathology, and to determine appropriateness of indications for colonoscopy in order to improve patient selection for colonoscopy.Methods This retrospective study includes 294 patients who were referred to the Gastroenterology Department from a primary carephysician in order to app...

By NERMA ČUSTOVIĆ, LEJLA DŽANANOVIĆ, ISMAR RAŠIĆ, NADŽA ZUBČEVIĆ, LEJLA ŠARANOVIĆ-ČEČO, JASMINA REDŽEPAGIĆ

09.10.2020. Review paper Biochemistry
Refractive errors in children: analysis among preschool and school children in Tuzla city, Bosnia and Herzegovina

Aim To establish the prevalence of refractive errors in preschool and school children between 4 and 15 years of age, living in Tuzla, Bosnia and Herzegovina.Methods Children from all elementary schools in the city of Tuzla and as well from eight day-care centres were screened for refractive errors in the period 2015-2019. Any child, who failed to p...

By AMRA NADAREVIĆ VODENČAREVIĆ, MELIHA HALILBAŠIĆ, ANIS MEĐEDOVIĆ, VAHID JUSUFOVIĆ, ADISA PILAVDŽIĆ, AIDA DRLJEVIĆ, MUFID BURGIĆ

09.10.2020. Review paper Biochemistry
Correlation of signal to noise ratio (SNR) value on distortion product otoacoustic emission (DPOAE) and expression of nuclear factor erythroid 2-related factor 2 (NRF2) in cochlear organ of Corti in rat exposed to noise

Aim To investigate the changes in the value of the signal to noise ratio (SNR) and to assess changes in the expression of nuclear factor erythroid 2-related factor 2 (NRF2) in the organ of Corti of rat exposed to noise.Methods This study used a randomized post test only control group laboratory experimental design with 27 male Wistar strain Rattus ...

By DIANA AMELLYA, TENGKU SITI HAJAR HARYUNA, WIBI RIAWAN

09.10.2020. Review paper Biochemistry
Correlation between numerical and categorical immunohistochemical score of Ki-67 and HER2 with clinicopathological parameters of breast cancer

Aim To evaluate the relationship between numerical and categorical immunohistochemical score of Ki-67 and human epidermal growth factor of receptor 2 (HER2) with clinicopathological parameters of breast cancer (BC).Methods The study included 311 patients with invasive BC diagnosed at the Department of Pathology, School of Medicine inSarajevo, Bosni...

By MIRSAD DORIĆ, SUADA KUSKUNOVIĆ-VLAHOVLJAK, EDINA LAZOVIĆ SALČIN, SVJETLANA RADOVIĆ, NINA ČAMDŽIĆ, MIRSAD BABIĆ, HARIS ČAMPARA

09.10.2020. Review paper Biochemistry
Posthumous sperm retrieval: a procreative revolution

Aim Postmortem sperm retrieval with consequent artificial insemination has become a technically possible option for future use in assisted reproductive technology (ART). The authors have set out to discuss the social and ethical significance of posthumous sperm retrieval, and the laws currently in force in Italy, the United Statesand elsewhere.Meth...

By FRANCESCA NEGRO, RENATA BECK, ANTONELLA COTOIA, MARIA CRISTINA VARONE

09.10.2020. Review paper Biochemistry
Serum total prostate-specific antigen (tPSA): correlation with diagnosis and grading of prostate cancer in core needle biopsy

Aim To investigate the impact of pre-treatment serum total prostate-specific antigen (PSA) level on prevalence of prostate carcinoma detection in prostate core needle biopsy, and its correlation with established prognostic factors.Methods Prostate needle biopsy samples of 115 patients with available pre-treatment serum total PSA (tPSA) level were a...

By NINA ČAMDŽIĆ, SUADA KUSKUNOVIĆ-VLAHOVLJAK, MIRSAD DORIĆ, SVJETLANA RADOVIĆ, EDINA LAZOVIĆ SALČIN, MIRSAD BABIĆ

09.10.2020. Review paper Biochemistry
Scrotal trauma: interest of preoperative ultrasound in the prediction of the rupture of the tunica albuginea

Aim Scrotal bruises are quite frequent injuries affecting young subjects, with psychological repercussions on body image and fertility. The interest of ultrasound in the context of the emergency remains controversial. The aim of our study was to investigate clinical, ultrasonographic and operative features of scrotal contusions, and to evaluate the...

By STEFANO MANNO, ANTONIO CICIONE, LORENZO BAGALÀ, ANTONIO CATRICALÀ, PIERO RONCHI, SIMONA TIBURZI, CAROLINA GIANNACE, LUCIO DELL’ATTI

09.10.2020. Review paper Biochemistry
Workload changes during the COVID-19 pandemic and effects on the flow of cancer patients in the Maxillofacial Surgery Department

Aim A SARS Coronavirus 2 (COVID-19) pandemic drastically changed the way the health system works. In Croatia, lockdownmeasures to curb virus spread lasted from March to May 2020, and all non-essential medical procedures and patients’ visits have been cancelled. The study aimed to compare patients’ flow and interventions in the surgical ...

By ANA KVOLIK PAVIĆ, VEDRAN ZUBČIĆ, SLAVICA KVOLIK

09.10.2020. Review paper Biochemistry
Brainstem haemorrhage as a rare complication of burr hole craniostomy

Aim Evacuation through burr hole craniostomy is the most common type of chronic subdural hematoma surgical treatment,with a morbidity rate of 0-9%.Methods Here we present a case of 66-year-old Caucasian woman with bilateral hemispheric chronic subdural hematoma andleft transtentorial uncal herniation. Bilateral burr hole craniostomy with gradual an...

By RODOLFO CORINALDESI, CORRADO FILIPPO CASTRIOTO, FRANCESCA ROMANA BARBIERI, LUCIANO MASTRONARDI, UMBERTO RIPANI

09.10.2020. Review paper Biochemistry
Application of a personal Santini technique in the resolution of a complex celiac trunk aneurysm - endovascular treatment

Aim Vascular pathologies have been already explored for the most of their aspects. It is a group of pathologies with unclear ethology and with an evolution in time not easy to forecast. Treatment guidelines are conflicting. The aim of this study was to describe cases in their most practical and technical aspect, especially in complicated conditions...

By GIANPAOLO SANTINI, PASQUALE QUASSONE, LUCA TAROTTO, FRANCESCO ARIENZO, GIUSEPPE SARTI

09.10.2020. Review paper Biochemistry
Current status of localized submental fat treatment with sodium deoxicolate (ATX-101)

Aim Facial aesthetics is at present a concept intricately linked to the degree of self-esteem. Unwanted submental fat (SMF) leads to an unattractive submental profile. Sodium deoxicolate (ATX) -101 is the only injectable drug approved to decrease submental fat of moderate to severe intensity.Methods We carried out a bibliographic review in PubMed u...

By CRISTINA IBÁÑEZ-VICENTE, MIGUEL CARRATO-GOMEZ, LUIGI MECCARIELLO, UMBERTO RIPANI, MICHELE BISACCIA

09.10.2020. Review paper Biochemistry
Does low intensity direct current affect open fracture wound healing?

Aim To explore the effects of a molecular pathway from the application of low-intensity direct current (LIDC) for wound healingthrough the pathway signalling growth factor and initiation of fibroblast activation.Methods This randomized clinical trial included 32 patients with open fracture wounds who came to Hasan Sadikin Hospital inBandung, Indone...

By YOYOS DIAS ISMIARTO, KEMAS ABDUL MUTHOLIB LUTHFI, MAHYUDIN MAHYUDIN, ADRIEL BENEDICT

09.10.2020. Review paper Biochemistry
Intermittent traction therapy in the treatment of chronic low back pain

Aim To investigate the effect of intermittent traction therapy (ITT) on pain in patients with chronic low back pain (CLBP).Methods A total of 81 patients with CLBP were included: experimental group received ITT (n=40) and control group receivedconservative physical treatment (n=41) 10 times for two weeks. A visual analogue scale (VAS) was used for ...

By EDINA TANOVIĆ, DAMIR ČELIK, ĐEMIL OMEROVIĆ, VANDA ZOVKO OMERAGIĆ, AMILA JAGANJAC, HADŽAN KONJO, EMINA ROVČANIN, HANA OMEROVIĆ

09.10.2020. Review paper Biochemistry
Efficacy of Zhu’s acupuncture techniques to improve muscle strength of motion limbs in stroke patients

AimTo investigate the efficacy of Zhu acupuncture in motoric ability improvement of stroke patients. This research is a preliminary study in an effort to test the efficacy of Zhu's acupuncture technique in motor improvement in stroke patients.Methods This quasi-experimental study, with the pretest and posttest approach without control group design ...

By INDRI SETA SEPTADINA, ERIAL BAHAR

09.10.2020. Review paper Biochemistry
The importance of education in patients with metabolic syndrome with regard to their knowledge and attitudes about the disease, and the impact of education on laboratory parameters

Aim A metabolic syndrome (MetS) increases the risk of heart disease and diabetes mellitus type 2, thus the aim of this study is tocorrelate the clinical and laboratory parameters in patients suffering from MetS who have previously had education compared to patients who have not had any education about a healthy lifestyle, and to check their knowled...

By AZRA BUREKOVIĆ, ELVIRA ĐOZO, ANIDA DIVANOVIĆ

09.10.2020. Review paper Biochemistry
Effects of semi-refined carrageenan (food additive E407a) on cell membranes of leukocytes assessed in vivo and in vitro

Aim To assess the impact of semi-refined carrageenan (E407a) on hydrophobic regions of phosphololipid bilayer in cell membranes of leukocytes collected from rats orally administered this food additive and white blood cells incubated with E407a.Methods Fluorescent probes (ortho-hydroxy derivatives of 2,5-diaryl-1,3-oxazole) were used to estimate the...

By ANTON TKACHENKO, ANATOLII ONISHCHENKO, ALEXANDER ROSHAL, OKSANA NAKONECHNA, TETYANA CHUMACHENKO, YEVGEN POSOKHOV

09.10.2020. Review paper Biochemistry
Biological augmentation strategies in rotator cuff repair

Rotator cuff tears (RCT) are a common problem encountered by orthopaedic surgeons. The incidence of re-tears (up to 94%) following surgical repair of RCTs renders the management of RCTs challenging. This higher re-tear rate has been attributed to the failure of healing at the tendon-bone junction. Biological augmentation methods such as growth fact...

By ERDI ÖZDEMIR, DOGAC KARAGUVEN, EGEMEN TURHAN, GAZI HURI

09.10.2020. Review paper Biochemistry
Arthroscopic labral repair with all-suture anchors: a magnetic resonance imaging retrospective study with a 2.5-year follow-up

Aim To evaluate radiological and clinical outcomes of a case series of patients affected by glenohumeral instability (Bankart lesion) or superior labrum tear from anterior to posterior (SLAP) lesions treated by arthroscopic repair using all-suture anchors.Methods Patients were operated by a single surgeon at a single Institution. Exclusion criteria...

By FEDERICO SACCHETTI, MARTINA DI MEGLIO, NICOLA MONDANELLI, NICOLA BIANCHI, VANNA BOTTAI, FEDERICO CARTEI, FABIO COSSEDDU, RODOLFO CAPANNA, STEFANO GIANNOTTI

09.10.2020. Review paper Biochemistry
Distal biceps tendon repair and posterior interosseous nerve injury: clinical results and a systematic review of the literature

Aim To report clinical, functional and radiographic results of oneincision distal biceps tendon repair with Toggle Loc (Zimmer-Biomet, Warsaw, Indiana, USA) at an average 4-year follow-up and to assess posterior interosseous nerve injury complications after reconstruction.Methods We conducted a retrospective review of 58 consecutive distal biceps t...

By SILVIO CHIOSSI, MARCO SPOLITI, PASQUALE SESSA, VALERIO ARCERI, ATTILIO BASILE, FRANCESCA ROMANA ROSSETTI, RICCARDO MARIA LANZETTI

09.10.2020. Review paper Biochemistry
A new technique of flexor carpi ulnaris transfer in multilevel surgery for upper extremity deformities in spastic cerebral palsy

Aim To assess treatment outcomes of cerebral palsy (CP) patients who underwent upper limb surgical treatment including new technique of flexor carpi ulnaris (FCU) transfer.Methods The study included an outcome of orthopaedic surgeries in 30 upper limbs of 25 CP patients aged 10 to 24 years (mean age of 15.1 years). In addition to standard orthopaed...

By GEORGY CHIBIROV, MAIRBEK PLIEV, DMITRY POPKOV

09.10.2020. Review paper Biochemistry
The challenge of the surgical treatment of paediatric distal radius/ forearm fracture: K wire vs plate fixation - outcomes assessment

Aim Distal radius/forearm fractures in adolescent patients remain challenging injuries to treat. Distal radius/forearm bony anatomy is not completely restored with intramedullary K wire fixation. The aim of this study was to compare radiographic and functional outcomes obtained using intramedullary K wire fixation and open reduction and internal fi...

By SALVATORE DI GIACINTO, GIUSEPPE PICA, ALESSANDRO STASI, LORENZO SCIALPI, ALESSANDRO TOMARCHIO, ALBERTO GALEOTTI, VLORA PODVORICA, ANNAMARIA DELL’UNTO, LUIGI MECCARIELLO

09.10.2020. Review paper Biochemistry
Modalities of extensor tendon repair related to etiological factors and associated injuries

Aim To evaluate modalities of extensor tendons repair of hand and forearm in specific anatomical zones with regard to etiological factors and presence of associated injuries of adjacent anatomical structures.Methods This cross-sectional study included 279 patients referred for extensor tendon repair of hand and forearm in specific anatomical zones....

By SANELA SALIHAGIĆ, ZLATAN ZVIZDIĆ, DŽENANA HRUSTEMOVIĆ, REDŽO ČAUŠEVIĆ, AHMAD HEMAIDI

09.10.2020. Review paper Biochemistry
Traumatic bilateral scaphoid fractures

Aim To illustrate the surgical treatment of bilateral post-traumatic scaphoid fracture.Methods We came across a young student, who sustained bilateral, undisplaced scaphoid waist fractures following a fall during afootball match. Despite careful clinical and radiographic evaluation by four views at the Accident and Emergency (A&E) Department, w...

By DARIUSH GHARGOZLOO, ALESSANDRO TOMARCHIO, MAURO BALLERINI, GIANPAOLO CHITONI

09.10.2020. Review paper Biochemistry
Impact of load on the knee in relation to a treadmill angle

Aim To determine the effect of the load on the meniscus in relation to a different angle, and to present the impact of force on eventual injury of menisci.Methods Research included 200 males with average height of 178.5 cm, mass 83.5 kg, and average age of 22 years. The simulation of treadmill that was used in the evaluation of ischemic heart disea...

By FIKRET VELJOVIĆ, EDIN BEGIĆ, AVDO VOLODER, REUF KARABEG, AMER IGLICA, NEDIM BEGIĆ, ALDEN BEGIĆ, ADISA CHIKHA

09.10.2020. Review paper Biochemistry
Radiographic evaluation of the tunnel position in single and double bundle anterior cruciate ligament reconstruction

Aim To evaluate tunnel positioning on radiographs in singlebundle (SB) and double-bundle (DB) anterior cruciate ligament(ACL) reconstruction, to evaluate if measurement is accurate and reproducible.Methods Radiographs of 30 SB and 30 DB ACL reconstruction were reviewed by two examiners who measured tunnel positioning with the quadrant method on the...

By MICHELE LOSCO, FRANCESCO GIRON, LUCA GIANNINI, PIERLUGI CUOMO, ROBERTO BUZZI, STEFANO GIANNOTTI, NICOLA MONDANELLI

09.10.2020. Review paper Biochemistry
Single use instruments for total knee arthroplasty

Aim Total knee arthroplasty represents a procedure that is successfully performed to relieve functional limitation and pain in advanced stages of osteoarthritis. In the next 20 years the number of these procedures will be increased about four times. Patient specific instrumentation (PSI) has been introduced in the past years. The aim of this study ...

By MICHELE ROMEO, GIUSEPPE ROVERE, LEONARDO STRAMAZZO, FRANCESCO LIUZZA, LUIGI MECCARIELLO, GIULIO MACCAURO, LAWRENCE CAMARDA

09.10.2020. Review paper Biochemistry
Medial pivot vs posterior stabilized total knee arthroplasty designs: a gait analysis study

Aim To compare a medial pivot (MP) total knee arthroplasty (TKA) with posterior stabilized (PS) TKA designs from a subjective, clinical and biomechanical point of view, in a single-centre, single-surgeon, case-control non-randomized trial.Methods Sixteen patients were randomly picked up from case series into each group. Subjective outcome was asses...

By NICOLA BIANCHI, ANDREA FACCHINI, NICOLA MONDANELL, FEDERICO SACCHETTI, ROBERTA GHEZZI, MARCO GESI, RODOLFO CAPANNA, STEFANO GIANNOTTI

09.10.2020. Review paper Biochemistry
Allogenic platelet concentrates from umbilical cord blood for knee osteoarthritis: preliminary results

Aim To investigate the role of cordonal blood platelet-rich plasma (PRP) intra-articular injections for treating the patients with kneeosteoarthritis in terms of procedure safety and clinical outcomes.Methods Twenty-five patients affected by knee osteoarthritis were enrolled and received one single intra-articular knee injection ofumbilical cord PR...

By VINCENZO CAIAFFA, FRANCESCO IPPOLITO, ANTONELLA ABATE, VITTORIO NAPPI, MICHELE SANTODIROCCO, DOMENICO VISCEGLIE

09.10.2020. Review paper Biochemistry
Intra-operative local plus systemic tranexamic acid significantly decreases post-operative bleeding and the need for allogeneic blood transfusion in total knee arthroplasty

Aim To evaluate the efficacy of systemic plus local tranexamic acid (TXA) in reducing post-operative bleeding, haemoglobin loss and the need for allogeneic blood transfusion (ABT) in total knee arthroplasty (TKA).Methods All patients undergoing TKA between January 2017 and September 2019 were retrospectively evaluated. Exclusion criteria were cardi...

By LIDIA DE FALCO, ELISA TROIANO, MARTINA CESARI, PIETRO AIUTO, GIACOMO PERI, NICOLÒ NUVOLI, MATTIA FORTINA, NICOLA MONDANELLI, STEFANO GIANNOTTI

09.10.2020. Review paper Biochemistry
Radiographic and functional outcome of complex acetabular fractures: implications of open reduction in spinopelvic balance, gait and quality of life

Aim To investigate the effects of surgical reduction of complex acetabular fractures on spine balance, postural stability and quality of life.Methods Twenty-six patients with acetabular fractures surgically treated by open reduction and internal fixation were divided intotwo groups according to the amount of reduction. Group A consisted of 18 patie...

By VITALIANO F. MUZII, GIUSEPPE ROLLO, GUIDO ROCCA, ROCCO ERASMO, GABRIELE FALZARANO, FRANCESCO LIUZZA, MICHELE BISACCIA, GIUSEPPE PICA, RAFFAELE FRANZESE, LUIGI MECCARIELLO

09.10.2020. Review paper Biochemistry
Key factors influencing clinical and functional outcomes in extracapsular proximal femur fractures: the role of early weightbearing - one-year follow-up cohort of 495 patients

Aim To establish a correlation between immediate post-surgical weight bearing in extracapsular hip fractures and final functional outcome as well as to study the correlation between immediate post-surgical weight bearing and morbidity and mortality during the first year.Methods Retrospective observational cohort study including 495 consecutive pati...

By ENRIQUE SANCHEZ-MUNOZ, BEATRIZ LOZANO-HERNANZ, DANIEL VICENTE VELARDE-GARRIDO, LETICIA ALARMA-BARCIA, VICTOR TRIVINO SANCHEZ-MAYORAL, PAULA ROMERA-OLIVERA, CRISTINA LOPEZ PALACIOS

09.10.2020. Review paper Biochemistry
Effectiveness of teriparatide combined with the Ilizarov technique in septic tibial non-union

Aim The septic non-union is a common compliance in bone healing due to bone infection. Bone resection, associated with Ilizarov osteo-distraction technique, is commonly used in these cases. The aim of this study was to analyse clinical and radiological results of teriparatide in combination with the Ilizarov technique and to compare this treatment ...

By GIUSEPPE ROLLO, FRANCESCO LUCERI, GABRIELE FALZARANO, CARLO SALOMONE, ENRICO MARIA BONURA, DMITRY POPKOV, MARIO RONGA, GIUSEPPE PICA, MICHELE BISACCIA, VALENTINA RUSSI, PREDRAG GRUBOR, RAFFAELE FRANZESE, GIUSEPPE M. PERETTI, LUIGI MECCARIELLO

09.10.2020. Review paper Biochemistry
Rare and uncommon diseases of the hip: arthroscopic treatment

Aim Uncommon and rare hip diseases are sources of pain and functional limitation particularly in young patients. Some of these conditions may be nowadays treated by arthroscopy due to the expertise and technical tips that high-volume hip arthroscopies have achieved during the last decades ensuring a wider range of indications for such a procedure. ...

By CHRISTIAN CARULLI, ALBERTO SCHIAVO, ALBERTO RIGON, WONDI DE MARCHI, MATTEO INNOCENTI, LUIGI MECCARIELLO, MASSIMO INNOCENTI

09.10.2020. Review paper Biochemistry
A new prognostic pelvic injury outcome score

Aim To propose a new prognostic classification system for pelvic injuries based on a new detailed and all-encompassing evaluation of the injury pelvic outcome score and to check the prognostic value of this classification and evaluate its reliability and reproducibility.Methods From January 2017 to June 2020 from 156 pelvic fractures treated at our...

By LUIGI MECCARIELLO, CRISTINA RAZZANO, CRISTINA DE DOMINICIS, JUAN ANTONIO HERRERA-MOLPECERES, FRANCESCO LIUZZA, ROCCO ERASMO, GUIDO ROCCA, MICHELE BISACCIA, ENZO PAGLIARULO, PIETRO CIRFEDA, DAVID GÓMEZ GARRIDO, GIUSEPPE PICA, GIUSEPPE ROLLO

09.10.2020. Review paper Biochemistry
Navigated percutaneous screw fixation of the pelvis with O-arm 2: two years’ experience

Aim To evaluate the case series of the patients operated with percutaneous fixation by the navigation system based on 3D fluoroscopic images, to assess the precision of a surgical implant and functional outcome of patients.Methods A retrospective study of pelvic ring fractures in a 2-year period included those treated with the use of the O-Arm 2 in...

By GIANLUCA CIOLLI, DANIELE CAVIGLIA, CARLA VITIELLO, SALVATORE LUCCHESI, CORRADO PINELLI, DOMENICO DE MAURO, AMARILDO SMAKAJ, GIUSEPPE ROVERE, LUIGI MECCARIELLO, LAWRENCE CAMARDA, GIULIO MACCAURO, FRANCESCO LIUZZA

09.10.2020. Review paper Biochemistry
Comparing hand strength and quality life of locking plate versus intramedullary k wire for transverse midshaft metacarpal fractures

Aim In the scientific literature there are no papers that clarify which method of surgical fixation in transverse metacarpal fractures has the best functional outcomes. The aim of this study was to compare the hand strength obtained using two different methods in the treatment of these fractures.Methods A total of 52 patients who presented a transv...

By ANDREA PASQUINO, ALESSANDRO TOMARCHIO, ENIO DE CRUTO, JACOPO CONTEDUCA, DAMIANO LONGO, VALENTINA RUSSI, GIUSEPPE PICA, LUIGI MECCARIELLO, GIUSEPPE ROLLO

09.10.2020. Review paper Biochemistry
Minimally invasive sinus tarsi approach in Sanders II-III calcaneal fractures in high-demand patients

Aim To evaluate if the sinus tarsi approach treated with open reduction and internal fixation (ORIF), without using plate fixation, provided good functional results in active adult population. The hypothesis was that the sinus tarsi approach with limited incision provided good results comparable to other approaches. Methods A total of 78 patients (...

By PAOLO CECCARINI, FRANCESCO MANFREDA, ROSARIO PETRUCCELLI, GIUSEPPE TALESA, GIUSEPPE RINONAPOLI, AURO CARAFFA

09.10.2020. Review paper Biochemistry
Balance assessment after altering stimulation of the neurosensory system

Aim Posture requires fine integrative elaboration, performed by the central nervous system, of neurosensory information originated from the visual, vestibular and spinal circuit. Many perturbing agents can influence this elaboration and then the postural stability. Several studies have evaluated only the effect of a single agent on the postural con...

By VALENTINA LI CAUSI, ALESSANDRO MANELLI, VALENTINA GIANPAOLA MARINI, MARIO CHERUBINO, LUIGI MECCARIELLO, MICHAEL MAZZACANE, MARIO RONGA

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