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Vol 21, No 2 (2024)

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Authors in this issue:

Armin Šljivo, Azra Durak-Nalbantić, Adel Smajlović, Adi Mulabdić, Adin Alijević, Admir Hadžimuratović, Ahmad Radaideh, Aida Brčić, Ajla Bečar-Alijević, Akif Mlačo, Aladin Altic, Alberto Verrotti, Alen Omanović, Ali Adel Dawood, Almedina Moro, Almira Ćosićkić, Alyaa Farouk Al-Omari, Amela Dedeić Ljubović, Amela Kulašević, Amela Selimović, Amina Marić, Amina Selimović, Amra Šerak, Anastasia Papaporfyriou, Andhika Yudistira, Andrea Stanclova, Arian Abdulkhaliq, Arie Utariani, Arif Budiman Susatya, Armin Šljivo, Athanasios Papatriantafyllou, Azra Hadžić-Kečalović, Belma Krdžalić-Zečević, Benjamin Ehle, Corinne Peek-Asa, Delila Softić, Denis Žigić, Devleta Balić, Dijana Dugonjić, Džanan Osmanović, Dženana Softić, Edin Hodžić, Edina Zahirović, Efstratios Koletsis, Elena Novakova, Elizeus Elizeus, Emina Dervišević, Emina Hadžimuratović, Emir Begagić, Emmanouil Dimopoulos, Emsad Halilović, Enver Zerem, Ery Satriawan Muammar, Faris Salihbašić, Fatima Gavrankapetanović, Federica Celi, Ferid Krupić, Francesk Mulita, George Pappas-Gogos, Georgios-Ioannis Verras, Gianluca Dini, Goran Borjanović, Goran Čerkez, Gordana Tešanović, Haris Zukić, Hasri Nopianto, Igor Knezović, Igor Sladojević, Ilma Dadić, Ioanna Akrida, Irma Fajić, Irma Salimović-Bešić, Joe E Cavanaugh, Kemal Grbić, Konstantinos Grapatsas, Konstantinos Tasios, Lana Lekić, Larisa Gavran, Lejla Kurtalić, Lejla Mešalić, Lejla Rakovac-Tupković, Leopold Reiter, Levan Tchabashvili, Mahendratama Purnama Adhi, Majda Mehmedović, Malik Alansari Abu Tabar, Manfred Dahm, Maria Grazia Santini, Martina Neuschlova, Marwan A. Ahmed, Melika Melunović, Michail Galanis, Mirela Bašić Denjagić, Mirela Lisičić-Konaković, Mirhan Salibašić, Mirna Alečković-Halilović, Moh Dliyauddin, Mohammad Alkhatatba, Monika Moravcova, Muhaimin Rifa’i, Mujo Kadrić, Namik Selimović, Nashi Widodo, Nejra Mlačo-Vražalić, Nermin Salkić, Nikolaos Charokopos, Nina Jovanović, Nina Мekić, Noviana Dwi Lestari, Olexander Bezsmertnyi, Olexander Branitsky, Olivera Batić-Mujanović, Panji Sananta, Parvaneh Lindström, Predrag Jovanović, Rapto Hardian, Ruri Vivian Nilamsari, Sadat Pušina, Sanimir Suljendić, Selma Mutevelić, Selma Terzić-Salihbašić, Senka Mesihović-Dinarević, Srdjan Nikolovski, Sri Rahayu, Sulistyo Mulyo Agustini, Suzana Arapčić, Suzana Savić, Svemir Čustović, Syaifullah Asmiragani, Tatiana Havrilova, Tatjana Bućma, Tatjana Jevtić, Vasileios Leivaditis, Vasiliki Garantzioti, Velma Rebić, Verica Mišanović, Verica Petrović, Viktor Shevchuk, Vincent Lucansky, Wahyu Isnia Adharini, Yurii Bezsmertnyi, Zayd Kays Omer, Zhang Ling, Ziyad Mohaidat, Zlatan Mehmedović,

Published: 01.09.2024.

Contents

01.09.2024. Review paper
Obesity and atherosclerosis in children

Atherosclerosis, one of the leading causes of death in developed countries is characterized by lumen reduction of blood vessels due to local thickening of internal blood vessels caused by plaque/atheroma. It begins in childhood, goes for a long time without manifesting symptoms, increasing with age it begins to seriously threaten health. The most i...

By SENKA MESIHOVIĆ-DINAREVIĆ

01.09.2024. Review paper
Urban thoracic trauma: diagnosis and initial treatment of non-cardiac injuries in adults

This comprehensive review aims to delineate the prevailing non-cardiac thoracic injuries occurring in urban environments following initial on-site treatment and subsequent admission to hospital emergency departments. Our study involved a rigorous search within the PubMed database, employing key phrases and their combinations, including "thoracic in...

By VASILEIOS LEIVADITIS, ATHANASIOS PAPATRIANTAFYLLOU, IOANNA AKRIDA, MICHAIL GALANIS, EMMANOUIL DIMOPOULOS, ANASTASIA PAPAPORFYRIOU, BENJAMIN EHLE, EFSTRATIOS KOLETSIS, NIKOLAOS CHAROKOPOS, GEORGE PAPPAS-GOGOS, FRANCESK MULITA, GEORGIOS-IOANNIS VERRAS, KONSTANTINOS TASIOS, VASILIKI GARANTZIOTI, LEVAN TCHABASHVILI, MANFRED DAHM, KONSTANTINOS GRAPATSAS

01.09.2024. Original article
The comparison of erector spinae plane block and caudal block for postoperative analgesia in paediatric surgery - meta-analysis

Aim To assess the efficacy of Erector Spinae Plane Block (ESPB) compared to caudal block in reducing postoperative pain in paediatric surgery.Methods An electronic literature search was conducted using the Cochrane Library, PubMed, and Google Scholar databases, with data collected from January 2018 until September 2023. This meta-analysis includes ...

By MAHENDRATAMA PURNAMA ADHI, RAPTO HARDIAN, ARIF BUDIMAN SUSATYA, ELIZEUS ELIZEUS, ARIE UTARIANI

01.09.2024. Original article
Out-of-hospital cardiac arrest (OHCA) in Bosnia and Herzegovina in the period 2018 -2022: current trends, usage of automated external defibrillators (AED) and bystanders’ involvement

Aim To investigate out-of-hospital cardiac arrest (OHCA) trend, provided advanced life support (ALS) measures, automated external defibrillator (AEDs) utilization and by-standers involvement in cardiopulmonary resuscitation (CPR) during OHCA incidents.Methods This cross-sectional study encompassed data pertaining to all OHCA incidents attended to b...

By ARMIN ŠLJIVO, TATJANA JEVTIĆ, SELMA TERZIĆ-SALIHBAŠIĆ, ARIAN ABDULKHALIQ, LEOPOLD REITER, FARIS SALIHBAŠIĆ, AJLA BEČAR-ALIJEVIĆ, ADIN ALIJEVIĆ, ILMA DADIĆ, FATIMA GAVRANKAPETANOVIĆ

01.09.2024. Original article
Predictors for major adverse cardiovascular events among patients with acute coronary syndrome in Bosnia and Herzegovina

Aim Despite advancements in the diagnosis, treatment and monitoring of patients with acute coronary syndrome (ACS), morbidity and mortality following ACS remain high. The aim of this study was to actively seek possible predictors of adverse outcomes after ACS aiming to identify high-risk patients promptly.Methods This retrospective cohort study inv...

By NAMIK SELIMOVIĆ, AMINA MARIĆ, ARMIN ŠLJIVO, ALADIN ALTIC, IRMA FAJIĆ, LANA LEKIĆ, AZRA DURAK-NALBANTIĆ

01.09.2024. Original article
Association of X-ray disease stage with basic patient data, laboratory values and treatment modalities in patients with seropositive rheumatoid arthritis

Aim To investigate whether the radiographic progression of rheumatoid arthritis (RA) correlates with inflammatory markers and other laboratory values, and its association with treatment modalities.Methods This observational study included 125 patients with seropositive RA. Data were obtained from patients’ medical records from the year of 202...

By ALEN OMANOVIĆ, NEJRA MLAČO-VRAŽALIĆ, AKIF MLAČO

01.09.2024. Original article
Association of overexpression of PLD6, CHRAC1 and PDCD5 with type 2 diabetes mellitus

Aim Diabetes type 2 (DT2) is a metabolic disease characterized by high blood sugar caused by insulin resistance and/or insufficient insulin production. The pathogenesis of DT2 is complicated by both genetic predisposition and environmental and lifestyle variables. At least 150 genetic variants have been linked to the probability of having DT2. The ...

By ALI ADEL DAWOOD, ZAYD KAYS OMER, ALYAA FAROUK AL-OMARI

01.09.2024. Original article
Use of tcdC gene sequencing to prevent misidentification of Clostridioides difficile ribotype 176 and 027

Aim To compare the sequences of the tcdC gene between Clostridioides difficile (C. difficile) strains identified as PCR ribotype 176 and the reference strain C. difficile PCR ribotype 027 and to evaluate the use of the Xpert C. difficile/Epi assay for their differentiation. Methods A total of 45 strains were grown from storage beads. DNA of su...

By TATIANA HAVRILOVA, ELENA NOVAKOVA, VINCENT LUCANSKY, ANDREA STANCLOVA, MARTINA NEUSCHLOVA

01.09.2024. Original article
Flu seasons during the period 2018-2023 in Sarajevo Canton, Bosnia and Herzegovina: possible impact of the SARS-CoV-2 pandemic on the influenza A and B virus circulation

Aim During the pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many countries reported a significant decrease in the prevalence of influenza virus cases. The study aimed to characterize the flu seasons from 2018 to 2023 in Sarajevo Canton, Bosnia and Herzegovina (B&H), and to assess the possible impact of the SARS-CoV-...

By ALMEDINA MORO, AMELA DEDEIĆ LJUBOVIĆ, EDINA ZAHIROVIĆ, SELMA MUTEVELIĆ, SUZANA ARAPČIĆ, GORAN ČERKEZ, IRMA SALIMOVIĆ-BEŠIĆ

01.09.2024. Original article
Less invasive surfactant administration versus intubation-surfactant-extubation in preterm infants: a retrospective study

Aim To compare the need for intubation and mechanical ventilation after surfactant delivery between less invasive surfactant administration (LISA)-treated and intuba-tion-surfactant-extubation (IN-SURE)-treated premature infants with respiratory distress syndrome (RDS). Methods Retrospective registry-based cohort study enrolled 36 newborns adm...

By GIANLUCA DINI, MARIA GRAZIA SANTINI, FEDERICA CELI, ALBERTO VERROTTI

01.09.2024. Original article
Diagnostic value of procalcitonin, C-reactive protein and leukocyte count in detecting acute appendicitis in paedi-atric patients - a single center experience

Aim To evaluate diagnostic reliability of accessible laboratory findings in recognition of acute appendicitis (AA). Methods A retrospective study included children aged 0-15 years with abdominal pain that lasted less than 5 days with at least two of the signs/symptoms - abdominal pain, tenderness of the lower right quadrant of the abdomen, "re...

By SANIMIR SULJENDIĆ, ALMIRA ĆOSIĆKIĆ, AZRA HADŽIĆ-KEČALOVIĆ, DENIS ŽIGIĆ

01.09.2024. Original article
Ultrasonographic parameters of the liver, spleen and kidney in a healthy paediatric population in Bosnia and Herzegovina: a prospective study

Aim To determine the normative range of ultrasound dimensions for the liver, spleen and kidneys in healthy children according to gender, age, body measurements, body surface area (BSA), and the influence of ethnicity on organ size.Methods The prospective study included children, ranging from full-term neonates to children aged 15, with normal ultra...

By NINA МEKIĆ, NERMIN SALKIĆ, AMELA SELIMOVIĆ, MAJDA MEHMEDOVIĆ, AIDA BRČIĆ, ZLATAN MEHMEDOVIĆ, AMRA ŠERAK, DIJANA DUGONJIĆ

01.09.2024. Original article
The correlation between nutritional status and diet quality with acute respiratory infections in preschool children aged 5 to 7 years

Aim To investigate the relationship between nutritional status (NS) and diet quality (DQ) with the frequency of acute respiratory infections (ARIs) in children aged 5 to 7 years.Methods Data were obtained through questionnaires. Anthropometric measurement, correlations between body mass index (BMI) and DQ with frequency of ARIs were analysed.Result...

By MELIKA MELUNOVIĆ, BELMA KRDŽALIĆ-ZEČEVIĆ, MIRELA LISIČIĆ-KONAKOVIĆ, AMELA KULAŠEVIĆ, LEJLA KURTALIĆ

01.09.2024. Original article
Prevalence of respiratory distress syndrome in premature twins compared to premature singletons

Aim To estimate prevalence of respiratory distress syndrome in preterm twins compared to preterm singletons. Methods This is a retrospective observational point prevalence study conducted at the level of three neonatal intensive care units. Medical records of all preterm newborns (<37 weeks of gestation) with respiratory distress syndrome t...

By EMINA HADŽIMURATOVIĆ, AMINA SELIMOVIĆ, ADMIR HADŽIMURATOVIĆ, VERICA MIŠANOVIĆ, VELMA REBIĆ, LEJLA KURTALIĆ

01.09.2024. Original article
Is there any difference in Lactobacillus abundance between age groups during ovarian stimulation in fresh in vitro fertilization (IVF) cycles?

Aim To investigate an influence of age and body mass index (BMI) as determinants of infertility treatment success in vitro fertilization (IVF) procedures confirmed so far, on the amount of Lactobacillus spp. (LS) and Gardnerella vaginalis (GV) in the endometrium in fresh IVF cycles at the time of embryo transfer.Methods This a prospective single-ce...

By HARIS ZUKIĆ, DEVLETA BALIĆ, DŽANAN OSMANOVIĆ

01.09.2024. Original article
The influence of anthropometric parameters on the concentration of globulin that binds sex hormones during the menopausal transition

Aim To determine the effect of body mass index (BMI) and waist-hip ratio (WHR) on the concentration of circulating sex hormone-binding globulin (SHBG) throughout the menopausal transition.Methods This cross-sectional study included 150 women divided into three groups: premenopausal (n=50), perimenopausal (n=50), and postmenopausal (n=50). The proce...

By DŽENANA SOFTIĆ, LEJLA MEŠALIĆ, DELILA SOFTIĆ

01.09.2024. Original article
Analysis of excessive corticosteroid use as an indicator of poor quality of care in patients with inflammatory bowel disease

Aim To evaluate the clinical impact of corticosteroids (CS) overuse in inflammatory bowel disease (IBD) patients. Excessive use of CS could delay more efficacious treatment and may indicate poor quality of care.Method This is a two-phase study that used Steroid Assessment Tool (SAT) to measure corticosteroid exposure in IBD patients. In the first p...

By MIRELA BAŠIĆ DENJAGIĆ, MIRNA ALEČKOVIĆ-HALILOVIĆ, LEJLA RAKOVAC-TUPKOVIĆ, PREDRAG JOVANOVIĆ, ZLATAN MEHMEDOVIĆ, ENVER ZEREM

01.09.2024. Original article
Surgical treatment and outcome of spinal arteriovenous malformations

Aim A rare and diverse set of abnormalities formed by spinal blood arteries known as spinal arteriovenous malformations (AVMs) has a higher risk of haemorrhage and morbidity, causing the shunting of blood from veins with an aberrant capillary bed to arteries. Knowledge of the vascular anatomy of spinal AVMs and the spinal cord's vascular supply is ...

By ANDHIKA YUDISTIRA, SYAIFULLAH ASMIRAGANI, ERY SATRIAWAN MUAMMAR

01.09.2024. Original article
Prognostic relevance of preoperative CA 19-9 values in stage III rectal adenocarcinoma: retrospective analysis and clinical implications

Aim To investigate prognostic significance of preoperative levels of the Carbohydrate anti-gen 19-9 (CA 19-9) in patients with stage III rectal adenocarcinoma who underwent a treatment at the Clinical Centre of the University of Sarajevo.Methods A retrospective cohort study included 84 patients who underwent radical anterior rectal resection due to...

By EDIN HODŽIĆ, SADAT PUŠINA, ADI MULABDIĆ, MIRHAN SALIBAŠIĆ, EMSAD HALILOVIĆ, MUJO KADRIĆ

01.09.2024. Original article
Paley cross union protocol for congenital pseudoarthrosis of the tibia

Aim Congenital pseudarthrosis of the tibia (CPT) is a rare, dysplastic condition causing significant disability in the lower limbs. A treatment aims to achieve long-lasting union, prevent limb length discrepancies, and prevent soft tissue lesions. Traditional surgery often yields satisfactory results, but amputation may be proposed in failed cases....

By PANJI SANANTA, HASRI NOPIANTO

01.09.2024. Original article
Pain propagation in the carpal tunnel syndrome: a quantitative sensory testing

Aim To determine the existence of damage to thin sensitive fibres (Aδ and C) by quantitative sensory testing (QST) in female patients with carpal tunnel syndrome (CTS), the existence of pain, and a connection with the in-nervation field of the nerve itself.Methods Forty-two consecutive female patients with symptoms of CTS participated in the ...

By TATJANA BUĆMA, IGOR SLADOJEVIĆ

01.09.2024. Original article
Ertl surgery on the short fibula stump after war injury

Aim To propose a new technique of Ertl-type surgery for significantly shortened and valgus deviated fibula stump. Methods We present the case of a 26-year-old patient who underwent reamputation surgery to replace a significantly shortened fibula stump using a distraction regenerate formed after tibial stump osteotomy and dosed distraction of t...

By VIKTOR SHEVCHUK, YURII BEZSMERTNYI, OLEXANDER BEZSMERTNYI, OLEXANDER BRANITSKY

01.09.2024. Original article
Clinical outcome of surgically treated displaced acetabular fractures with central dislocation using combined anterior and medial plating

Aim Acetabular fractures are complex articular fractures with a big challenge for orthopaedic surgeons. Surgically managed displaced fractures carry favorable outcomes, especially if the articular surface is reduced accurately. This study aims to assess the clinical outcomes of surgical-ly fixed displaced acetabular fractures with central dislocati...

By AHMAD RADAIDEH, MALIK ALANSARI ABU TABAR, ZIYAD MOHAIDAT, MOHAMMAD ALKHATATBA, MARWAN A. AHMED

01.09.2024. Original article
Essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins on erythrocyte (TER-119) cells in diabetic mouse models

Aim To evaluate the essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins through CD55 and CD59 on erythrocyte (TER-119).Methods Strepto-zotocin (145 mg/kg) was used to induce diabetes mice. In diabetes mellitus (DM) model mice were treated with MA formulation for 14 days at a D1 - 500 mg/kg (M) + 6...

By NOVIANA DWI LESTARI, SULISTYO MULYO AGUSTINI, MOH DLIYAUDDIN, WAHYU ISNIA ADHARINI, RURI VIVIAN NILAMSARI, NASHI WIDODO, SRI RAHAYU, MUHAIMIN RIFA’I

01.09.2024. Original article
Assessment of the risk of falls among elderly persons in primary care settings

Aim To investigate the risk for falls in elderly patients treated in the Primary Health Care Centre Gradiška, Bosnia and Herzegovina.Methods This study included 500 patients aged 65 and older. They were chosen randomly by 10 family physicians. Data collection took place every Wednesday and Friday, between January 2022 and July 2022. The pati...

By SUZANA SAVIĆ, LARISA GAVRAN, VERICA PETROVIĆ, GORDANA TEŠANOVIĆ, OLIVERA BATIĆ-MUJANOVIĆ, GORAN BORJANOVIĆ

01.09.2024. Original article
Association between paediatric eye injuries, later aca-demic success and social performance

Aim To investigate an association between eye injury and later academic and social performance.Methods A retrospective longitudinal study of taking measurements multiple times was conducted including all severe eye injuries admitted during 2011-2017 at the main regional clinic to investigate changes in academic success and social inclusion before a...

By NINA JOVANOVIĆ, CORINNE PEEK-ASA, ZHANG LING, JOE E CAVANAUGH, ADEL SMAJLOVIĆ, SRDJAN NIKOLOVSKI, EMIR BEGAGIĆ, IGOR KNEZOVIĆ

01.09.2024. Original article
When time does not heal all wounds: three decades’ experience of immigrants living in Sweden

Aim To investigate how immigrants from the Balkan region experienced their current life situation after living in Sweden for 30 years or more. Methods The study was designed as a qualitative study using data from interviews with informants from five Balkan countries. The inclusion criteria were informants who were immigrants to Sweden and had ...

By FERID KRUPIĆ, MONIKA MORAVCOVA, EMINA DERVIŠEVIĆ, SVEMIR ČUSTOVIĆ, KEMAL GRBIĆ, PARVANEH LINDSTRÖM

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