Aim In order to increase the database related to the antineoplastic potential of metformin, association between the use of metformin and risk of cancer occurence in patients with diabetes mellitus type 2 (DM2) was investigated. Methods In this cross-sectional study, medical records of patients with DM2 were reviewed for cancer occurence. Data on ag...

By Jasna Kusturica, Aida Kulo Ćesić, Edis Gušić, Sanita Maleškić, Maida Rakanović-Todić, Damir Šečić

Aim To investigate biosynthesis in nitric oxide (NO) during normal pregnancy and in pregnancies complicated by preeclampsia. Methods This prospective cross-sectional study included 80 patients hospitalized at the Department of Women's Health, Neonatology and Perinatology Cantonal Hospital in Zenica. Serum NO concentration in 20 non-pregnant women, ...

By Jasmin Hodžić, Sebija Izetbegović, Bedrana Muračević, Rasim Iriškić, Hana Štimjanin Jović

Aim To evaluate immobilization with dorsal forearm plaster splint with the wrist in dorsal flexion vs palmar flexion in patients with distal radius fracture. Methods In the prospective study (2012-2014) 122 patients (of which 22 patients lost) with fractures of the distal radius type A2, A3 and C according to the AO classification were investigated...

By Maki Grle, Miro Miljko, Ivana Grle, Faruk Hodžić, Tarik Kapidžić

Aim To investigate an impact of various biological, psychological and social factors on perpetration of criminal offences by persons with mental disorders and to examine legal requirements for placement of persons with mental disorders, who committed criminal offences. Methods This retrospective, descriptive study based on the analysis of data coll...

By Edin Bjelošević, Adisa Krehmić, Halima Hadžikapetanović, Sanel Čoralić, Sonja Bjelošević

Aim To compare finding of thyroid gland scintigraphy with serum concentration of parathyroid hormone in patients undergoing hemodialysis. MethodsThis retrospective-prospective study included 50 patients undergoing hemodialysis with established hyperparathyroidism who were treated at Cantonal Hospital Zenica in the period 2009-2014. Besides anthropo...

By Nermana Ahmetbegović, Nadira Suljagić, Vahidin Katica

Aim To identify modes of venous thromboembolism (VTE) prophylaxis in patients undergoing elective major orthopaedic surgery (total hip or knee arthroplasty, THA/TKA) at a single university-associated hospital in Croatia. Methods A retrospective analysis of consecutive patients subjected to THA or TKA over a two-year period (2014-2015) with a focus ...

By Robert Kolundžić, Marijana Šimić Jovičić, Maja Ðinkić, Tadija Petrović, Tomislav Crnković, Vladimir Trkulja

Aim The aim of this study is to investigate the possibilities of non-invasive diagnostic imaging methods, positron emission tomography/computed tomography (PET/CT) and CT, in clinical N staging of non-small cell lung cancer (NSCLC). Methods Retrospective clinical study included 50 patients with diagnosed NSCLC who have undergone PET/CT for the purp...

By Sandra Vegar Zubović, Spomenka Kristić, Besima Hadžihasanović

Aim To investigate total homocysteine (tHcy) serum concentration in patients with probable vascular dementia (VD) and in agematched controls, as well as to determine an association between tHcy serum concentration and cognitive impairment in patients with probable VD. Methods Serum concentration of tHcy was determined by the Fluorescence Polarizati...

By Salem Alajbegović, Orhan Lepara, Almira Hadžović-Džuvo, Alma Mutevelić-Turković, Lejla Alajbegović, Asija Zaćiragić, Nesina Avdagić, Amina Valjevac, Nermina Babić, Amela Dervišević

Aim The evaluation of biomarkers of acute ischemic brain injury following surgical revascularization of the heart with the use of the heart-lung machine (cardiopulmonary bypass, CPB).Methods Twenty consecutive patients were divided into two groups: the first 10 patients received a potential neuroprotective humanrecombinant erythropoietin, while the...

By Milan Skitek, Aleš Jerin

Aim To evaluate efficacy and safety of iris-supported phakic lenses (Verisyse) for treating moderately high myopia.Methods This prospective clinical study included 40 eyes from 29 patients, who underwent implantation of Verisyse for correction ofmyopia from -6.00 to -14.50 diopters (D) in the Eye Clinic ‘’Svjetlost’’, Saraje...

By Melisa Ahmedbegović Pjano, Amila Alikadić-Husović, Senad Grišević, Adis Pašalić, Ajla Pidro, Mirko Ratković, Maja Bohač, Nikica Gabrić, Refet Gojak