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Edited by:

Selma Uzunović

Vol 21, No 2 (2024):

Medicinski Glasnik

Published: 01.09.2024.

Current issue
01.09.2024. Review paper
Obesity and atherosclerosis in children

By Senka Mesihović-Dinarević

01.09.2024. Review paper
Urban thoracic trauma: diagnosis and initial treatment of non-cardiac injuries in adults

By Vasileios Leivaditis, Athanasios Papatriantafyllou, Ioanna Akrida, Michail Galanis, Emmanouil Dimopoulos, Anastasia Papaporfyriou, Benjamin Ehle, Efstratios Koletsis, Nikolaos Charokopos, George Pappas-Gogos, Francesk Mulita, Georgios-Ioannis Verras, Konstantinos Tasios, Vasiliki Garantzioti, Levan Tchabashvili, Manfred Dahm, Konstantinos Grapatsas

01.09.2024. Original article
The comparison of erector spinae plane block and caudal block for postoperative analgesia in paediatric surgery - meta-analysis

By Mahendratama Purnama Adhi, Rapto Hardian, Arif Budiman Susatya, Elizeus Elizeus, Arie Utariani

01.09.2024. Original article
Out-of-hospital cardiac arrest (OHCA) in Bosnia and Herzegovina in the period 2018 -2022: current trends, usage of automated external defibrillators (AED) and bystanders’ involvement

By Armin Šljivo, Tatjana Jevtić, Selma Terzić-Salihbašić, Arian Abdulkhaliq, Leopold Reiter, Faris Salihbašić, Ajla Bečar-Alijević, Adin Alijević, Ilma Dadić, Fatima Gavrankapetanović

01.09.2024. Original article
Predictors for major adverse cardiovascular events among patients with acute coronary syndrome in Bosnia and Herzegovina

By Namik Selimović, Amina Marić, Armin Šljivo, Aladin Altic, Irma Fajić, Lana Lekić, Azra Durak-Nalbantić

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22.09.2019. Review paper
Impact of hand hygiene knowledge on the hand hygiene compliance

By Martin Novák, Jozef Breznický, Jana Kompaníková, Nora Malinovská, Henrieta Hudečková

Aim
Hand hygiene practice is still burdened by inadequate compliance, whether in the professional sphere by health professionals or in the non-professional sphere by lay population. Aim of this study was to map the hand hygiene knowledge and its compliance in the monitored group of people.
Methods
The research was conducted at the Jessenius Faculty of Medicine in Martin of Comenius University in Bratislava (JFM CU) among seventy 3 rd year students of General Medicine (medical study program), and Nursing, Midwifery and Public Health (non-medical study programs). Knowledge of hygienic hand washing according to the WHO guidelines from 2009 was investigated, as well as differences in the level of microbial contamination of hands after routine hand washing between the group that had been acquainted with hand hygiene protocols and the group that had not sufficiently.
Results
The results have shown that 32.9% of the students did not perform hygienic hand washing properly. The differences between the groups of students with and without the proper hand hygiene compliance in routine hand washing were not statistically significant. Conclusion
The results of our survey have suggested that the reasons for decreased compliance with hand washing protocols may be related to forgetting to wash the hands or not being acquainted with hand washing protocols at all. The strategies focused only on one aspect of hand hygiene are, according to scientific literature, ineffective in the long term.

12.07.2020. Review paper
The effect of Aloe vera ethanol extract on the growth inhibition of Candida albicans

By Via Karina Nabila, Imam Budi Putra

06.11.2023. Review paper
ChatGPT's contributions to the evolution of neurosurgical practice and education: a systematic review of benefits, concerns and limitations

By Hakija Bečulić, Emir Begagić, Rasim Skomorac, Anes Mašović, Edin Selimović, Mirza Pojskić

01.09.2024. Review paper
Obesity and atherosclerosis in children

By Senka Mesihović-Dinarević

01.09.2024. Review paper
Urban thoracic trauma: diagnosis and initial treatment of non-cardiac injuries in adults

By Vasileios Leivaditis, Athanasios Papatriantafyllou, Ioanna Akrida, Michail Galanis, Emmanouil Dimopoulos, Anastasia Papaporfyriou, Benjamin Ehle, Efstratios Koletsis, Nikolaos Charokopos, George Pappas-Gogos, Francesk Mulita, Georgios-Ioannis Verras, Konstantinos Tasios, Vasiliki Garantzioti, Levan Tchabashvili, Manfred Dahm, Konstantinos Grapatsas

This comprehensive review aims to delineate the prevailing non-cardiac thoracic injuries occurring in urban environments following initial on-site treatment and subsequent admission to hospital emergency departments. Our study involved a rigorous search within the PubMed database, employing key phrases and their combinations, including "thoracic injury," "thoracic trauma," "haemothorax," "lung contusion," "traumatic pneumothorax," "rib fractures," and "flail chest." We focused on original research articles and reviews. Non-cardiac thoracic injuries exhibit a high prevalence, often affecting poly-trauma patients, and contributing to up to 35% of polytrauma-related fatalities. Furthermore, severe thoracic injuries can result in a substantial 5% mortality rate. This review provides insights into clinical entities such as lung contusion, traumatic haemothorax, pneumothorax, rib fractures, and sternal fractures. Thoracic injuries represent a frequent and significant clinical concern for emergency department physicians and thoracic surgeons, warranting thorough understanding and timely intervention.

12.07.2020. Review paper
Epidemiology of injuries connected with dance: a critical review on epidemiology

By Giuseppe Rinonapoli, Marta Graziani, Paolo Ceccarini, Cristina Razzano, Francesco Manfreda, Auro Caraffa

12.07.2020. Review paper
Combination of vitamin A and D supplementation for ischemic stroke: effects on interleukin-1ß and clinical outcome

By Alfansuri Kadri, Hasan Sjahrir, Rosita Juwita Sembiring, Muhammad Ichwan

01.09.2024. Original article
Predictors for major adverse cardiovascular events among patients with acute coronary syndrome in Bosnia and Herzegovina

By Namik Selimović, Amina Marić, Armin Šljivo, Aladin Altic, Irma Fajić, Lana Lekić, Azra Durak-Nalbantić

01.09.2024. Original article
Use of tcdC gene sequencing to prevent misidentification of Clostridioides difficile ribotype 176 and 027

By Tatiana Havrilova, Elena Novakova, Vincent Lucansky, Andrea Stanclova, Martina Neuschlova

Aim
To compare the sequences of the tcdC gene between Clostridioides difficile (C. difficile) strains identified as PCR ribotype 176 and the reference strain C. difficile PCR ribotype 027 and to evaluate the use of the Xpert C. difficile/Epi assay for their differentiation. 
Methods
A total of 45 strains were grown from storage beads. DNA of sufficient quality and quantity for sequencing was extracted from 9 samples. Single consensus sequences of PCR ribotype 176 strains and PCR ribotype 001, PCR ribotype 070 (a control group) were mapped to a reference genome of strain CDI-01 (PCR ribotype 027). 
Results
Four strains (out of seven; 57%) characterized as PCR ribotype 176 had 100% identity of the tcdC gene with the reference strain. The average length of the tcdC gene in these four strains (PCR ribotype 176) was 643 bp, which is 36 bp shorter than the reference genome. Three strains (PCR ribotype 176) had a percentage identity of the tcdC gene in the range of 99.37-100%. Strains 25 (PCR ribotype 001) and 28 (PCR ribotype 070) had a similarity in the range of 95.39-95.63% as a result of different ribotype to the reference strain. 
Conclusion
PCR ribotype 176 strains have almost the same tcdC gene sequence as PCR ribotype 027, resulting in misidentification of this PCR ribotype by the Xpert C. difficile/Epi assay. Information about presumptive positive results based on deletion in the tcdC gene should be treated with caution or disregarded.

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