Aim Senduduk fruit (Melastoma malabathricum L) is native to Indomalaya and is believed to possess anticancer activity. This study investigated antiangiogenic and anti-inflammation effects of an ethanolic extract of Senduduk fruit (EESF) on HeLa cells. Methods Cytotoxicity was assayed in HeLa cell cultures exposed to a concentration series of 500-7....

By Deri Edianto, Aznan Lelo, Syafruddin Ilyas, Marline Nainggolan

Aim Phlebotominae sandflies are primary vectors of phleboviruses, causing the sandfly fever disease. The aim of this study was to detect and report the presence of flaviviruses in Phlebotominae sandflies captured in Bosnia and Herzegovina. Methods After a microscopic and morphometric analysis, the final identification of collected Phlebotomus speci...

By Mirsada Hukić, Halida Avdihodžić, Ivan-Christian Kurolt, Alemka Markotić, Jasna Hanjalić, Lejla Kapur-Pojskić, Irma Mahmuljin, Monia Avdić, Irma Salimović-Bešić, Lejla Smajlović-Skenderagić

Aim Stroke is one of the leading causes of adult disability and functional impairment worldwide. Cognitive impairments including memory dysfunction are common after stroke and may have a negative impact to the functional status and activities of daily living (ADL). The study aimed to determine the impact of working memory impairment after stroke on...

By Fasihah Irfani Fitri, Aida Fithrie, Aldy S Rambe

Aim To determine the effect of roselle (Hibiscus sabdariffa) petals in dextran sodium sulfate (DSS)-induced colitis model by measuring pro-inflammatory cytokines expressions (IL-6, and TNF-α), anti-inflammatory cytokine expression (IL-10) and histological colitis inflammation score (HCIS). Methods This study was conducted in two phases. For t...

By Masrul Lubis, Gontar Alamsyah Siregar, Hakim Bangun, Syafruddin Ilyas

Aim Steady progress in intensive treatment worldwide has increased the survival of immature neonates, but with multiple invasive procedures, which have increased the risk of infection, thus the bacterial resistance to antibiotics. The aim of this study was to analyse the epidemiology of multidrug resistance pathogens as causative agents of neonatal...

By Devleta Hadžić, Fahrija Skokić, Selmira Brkić, Amina Saračević, Delila Softić, Dženana Softić

Aim To examine whether preoperative tumour size may serve as a biomarker for the occurrence of lymphovascular invasion (LVI) in centrally and peripherally located lung adenocarcinoma. Method The study included 261 patients surgically treated for diagnosed lung adenocarcinoma. A ROC curve was used to determine the biomarker potential of tumour size ...

By Kemal Grbić, Bakir Mehić, Dalma Udovičić-Gagula, Amina Valjevac, Adem Ćemerlić, Ferid Krupić

Aim To demonstrate the analgesic effect of preemptively administered tramadol and metamizole on the postoperative pain severity, after an elective operative hysterectomy with adnexectomy. Methods There were three groups with 30 patients in each group. Patients included in the study were between 45 to 67 years old. They were all in the ASA group II....

By Ismet Suljević, Muamer Hadžiavdić, Ismana Šurković, Omer Suljević, Maida Turan, Ehlimana Mušija

Aim To investigate the relationship between IL-6 concentration and the risk of carotid artery calcification in chronic kidney disease patients with dialysis (CKD-5D). Methods This analytic observational cross-sectional study includes 95 clinically stable patients who underwent regular haemodialysis for at least three months at Rasyida Renal Hospita...

By Riri Andri Muzasti, Herman Hariman, Elvita Rahmi Daulay

Aim To investigate effect of bay leaf extract in endothelial integrity, observed by vascular endothelial growth factor (VEGF) level, VEGF and CD31 expression. Methods Thirty-two acute coronary syndrome surgery-induced Wistar Rats (Rattus novergicus) were divided into 16 bay leaf extract (treatment) groups and 16 control groups, sacrificed on day 1,...

By Refli Hasan, Siregar Gontar Alamsyah, Dharma Lindarto

Aim Candida albicans can cause two major types of infections: superficial infections (such as oral or vaginal candidiasis) as well as life-threatening systemic infections, and Aloe vera extract is one of the potentially useful therapeutic options. The aim of this study was to determine antifungal properties of Aloe vera ethanol extract on vulvovagi...

By Via Karina Nabila, Imam Budi Putra