Demographic and epidemiologic evaluation of mushroompoisoning: a retrospective study in 4-year admissions of Razi Hospital (Qaemshahr, Mazandaran, Iran)
Aim Wild mushroom intoxication is a public health problem, which causes a wide range of symptoms: from mild gastrointestinal symptoms to multiple organ failure and death. The present study aims to evaluate the epidemiology of mushroom intoxication in 4-year admissions of Razi Hospital, Qaemshahr, Mazandaran, Iran. Methods Medical records of all identified cases of mushroom poisoning admitted during the period between 2015 and 2018 were extracted and patients' demographic data including age, sex, latency period, season of poisoning, clinical presentations, laboratory findings, prognosis, duration of hospitalization and therapeutic interventions were recorded. Results A total of 65 mushroom poisoning cases were identified (mean age of 35.68 years), of which 32 (49.2%) were females. Latency of ≤ 6 hours was seen in 63 (96.4%) cases. The most prevalent season of intoxication was spring (60.7%). The most frequent symptoms were nausea and vomiting (86.5%) and abdominal pain (51.2%). No case required intensive care unit (ICU) care or mechanical ventilation. Mean hospital stay was 1.89 days without any mortality. Mean aspartate aminotransferase (AST) level was 21.89 (±9.55), but the disturbance of liver function tests (LFTs), coagulopathy, elevated level of bilirubin and/or platelet was not noted. In 93% of patients ranitidine, in 7% Penicillin G, and in 3.6% cefaclor and ceftriaxone was administrated. Conclusion People and health care providers must be educated about mushroom poisoning. Prompt transfer of suspicious cases with history of wild mushroom ingestion to the emergency department is crucial since patients showing toxicity symptoms after 6 hours might have worse and mortal prognosis despite treatment.
Sm A, Jm H, Bd H, El-Setouhy M, Gs S, Ml S. Epidemiology of acute poisoning in children presenting to the Poisoning Treatment Center at Ain Shams University In Cairo. Clinical Toxicol (Phila). 2009;20–6.
2.
Subhedar A, Janardhan K. Incidence and pattern of poisoning in children under 18 years of age. Ind J Pubhealth Res Dev. 2016;30–8.
3.
Büchner R, Hatvani L, Vágvölgyi C, Manczinger L, Kredics L, Is D. 18th Danube-Kris-Mures-Tisa (DKMT) Euroregional Conference on Environment and Health: Book of abstracts. 2016;84–5.
4.
Lamireau T, Llanas B, Kennedy A, Fayon M, Penouil F, Favarell-Garrigues J. Epidemiology of poisoning in children: a 7-year survey in a paediatric emergency care unit. Eur J Emerg Med. 2002;9–14.
5.
Chen Z, Zhang P, Zhang Z. Investigation and analysis of 102 mushroom poisoning cases in southern china from 1994 to. Fungal Diversity. 2012;123–31.
6.
Manouchehrifar M, Derakhshandeh N, Shojaee M, Sabzghabaei A, Farnaghi F. An epidemiologic study of pediatric poisoning; a six-month cross-sectional study. Emergency. 2016;21.
7.
Schmutz M, Carron PN, Yersin B, Trueb L. Mushroom poisoning: a retrospective study concerning 11-years of admissions in a swiss emergency department. Intern Emerg Med. 2018;59–67.
8.
Cervellin G, Comelli I, Rastelli G, Sanchis-Gomar F, Negri F, Luca D, et al. Epidemiology and clinics of mushroom poisoning in northern italy: a 21-year retrospective analysis. Hum Exp Toxicol. 2018;697–703.
9.
Pajoumand A, Shadnia S, Efricheh H, Mandegary A, Hassanian-Moghadam H, Abdollahi M. A retrospective study of mushroom poisoning in iran. Hum Exp Toxicol. 2005;609–13.
10.
Sh E, Demirel Y, Ugurlu S, Korkmaz I, Aktas C, Fmk G. Mushroom poisoning: retrospective analysis of 294 cases. Clinics. 2010;491–6.
11.
Cheung S, Wwy C, Wy H, Pk C, Law T. Food Poisoning Case Studies: Mushroom And Pufferfish Toxin Investigation. 2017;
12.
Diaz J. Mistaken mushroom poisonings. Wilderness Environ Med. 2016;330–5.
13.
Keller S, Klukowska-Rötzler J, Schenk-Jaeger K, Kupferschmidt H, Exadaktylos A, Lehmann B, et al. Mushroom poisoning-a 17 year retrospective study at a level i University Emergency Department in Switzerland. Int J Environ Res Public Health. 2018;15.
14.
Dadpour B, Tajoddini S, Rajabi M, Afshari R. Mushroom poisoning in the northeast of iran; a retrospective 6-year epidemiologic study. Emerg (Tehran). 2017;23.
15.
Lincoff G, Mitchel D. Toxic And Hallucinogenic Mushroom Poisoning. A Handbook For Physicians And Mushroom Hunters. 1977;
16.
Jp H, Ma G. Mushroom poisoning: case reports and a review of therapy. JAMA. 1984;1057–61.
17.
Trestrail J. Mushroom poisoning in the united states-an analysis of 1989 united states poison center data. J Toxicol Clin Toxicol. 1991;459–65.
18.
Cassidy N, Duggan E, Tracey J. Mushroom poisoning in ireland: the collaboration between the national poisons information centre and expert mycologists. Clin Tox. 2011;171–6.
19.
Km SJ, Rauber-Lüthy C, Bodmer M, Kupferschmidt H, Ga KU, Ceschi A. Mushroom poisoning: a study on circumstances of exposure and patterns of toxicity. Euro J Intern Med. 2012;85–91.
20.
Chan Y, Chan C, Ng C, Ng S, Lau K, Tse M. Hong Kong J Emerg Med. 2016;244–54.
21.
Wiseman H, Guest K, Murray V, Volans G. Accidental poisoning in childhood: a multicentre survey. 1. General epidemiology. Human Toxicol. 1987;293–301.
22.
Badsar A, Taramsari R, M, Maafi A, A, Rad R, et al. Mushroom poisoning in the southwest region of the Caspian sea, Iran: a retrospective study. Iran J Toxicol. 2013;798–803.
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