Aim Mesenchymal stem cells (MSCs) have potent immunosuppressive properties to control systemic lupus erythematosus (SLE) disease by inhibiting indoleamine 2,3-dioxygenase (IDO), and increasing regulatory T cells (Treg) to control innate and adaptive immune cells. However, the interaction and mechanism regarding IDO and B cells in the co-culture of ...

By Dewi Masyithah Darlan, Delfitri Munir, Agung Putra, Iffan Alif, Nur Dina Amalina, Nelva Karmila Jusuf, Imam Budi Putra

Aim Chromosome translocations are considered as one of the most severe forms of genome defects. Because of the clinical significance of chromosome translocations and scarce data on the incidence of sporadic translocations in population of Bosnia and Herzegovina, we aimed to report sporadic translocation frequencies in samples karyotyped in our labo...

By Sanin Haverić, Anja Haverić, Maida Hadžić, Tamara Ćetković, Lejla Čaluk Klačar, Rifat Hadžiselimović

Aim Plastic clips are a diamagnetic material and produce fewer artefacts in the MR field than titanium clips, which are standardin neurosurgery. However, alongside their physical properties, the shape of the clips, and their very geometry subtlety affects their behaviour in the magnetic field. Therefore, we performed a simulation in order to establ...

By Samir Delibegović, Mirza Batalović, Mirela Delibegović, Tarik Bujaković

Lenticulostriate vasculopathy (LSV) is a relatively common fi nding in routine cranial ultrasound examination that has been associated with many infectious and non-infectious conditions. The aim of this review was to provide a better understanding of LSV ultrasound fi nding, as well as the need for further laboratory and imaging examinations in inf...

By Suada Heljić, Hajrija Maksić, Sabina Terzic

Aim COVID-19 pandemic caused by SARS-CoV-2 is spreading throughout the world affecting both healthy individuals and people with underlying immune-deficiencies. People living with human immunodeficiency virus (HIV) consist a group multiply affected by this universal crisis.Methods Literature search aiming to identify relevant publications referring ...

By Dimitrios Bousis, Francesk Mulita, Ioanna Marlafeka, Themistoklis Paraskevas, Dimitrios Velissaris

Aim To assess a psychosocial impact of the Coronavirus disease 2019 (COVID-19) on health care workers and to quantify the size of depression symptoms, anxiety and stress levels.Methods This cross-sectional study used an anonymous online survey questionnaire as a research instrument and it included 114health workers of all profiles from the Sarajevo...

By Aleksandra Pašić, Slavenka Štraus, Emina Smajić, Ermin Begović, Ilirijana Haxhibeqiri-Karabdić, Nada Spasojević

Aim Knee osteoarthritis is a common osteoarthritis, which limits individual’s activity and affects aspects of daily life and quality of life. The prevalence of osteoarthritis in Indonesians is still high, reaching 12.7% in women and 15.8% in men. Based on the WHO, the prevalence of osteoarthritis in the world is still high, with 18% in women ...

By Panji Sananta, Avicenna Rahmanda, Dhelya Widasmara, Eka Noviya Fuzianingsih

Aim Bone defect is a challenge even for experienced orthopaedic surgeons and it is a significant cause of morbidity in patients and a source of high economic burden in health care. A severe bone defect is a condition whereby the bone tissue cannot undergo natural healing despite surgical stabilization and requires further surgical intervention. Str...

By Panji Sananta, Respati S Dradjat, Rizqi Daniar Rosandi, Lasa Dhakka Siahaan

Aim To investigate changes in bone and cartilage tissue during the use of non-steroidal anti-inflammatory drugs and paracetamol in experimental osteoarthritis and hypothyroidism by the markers CTX-I and CTX-II.Methods The experiments were performed on 75 white nonlinear rats of both sexes, which recreated osteoarthritis and hypothyroidism. Experime...

By Dmytriy Sergeevich Nosivets

Aim To investigate possible differences in serum glucose and sodium and potassium concentrations with respect to age, gender and severity of diabetic ketoacidosis.Methods Medical records from 1 January 2017 to 31 December 2019 were reviewed and patients with the diagnosis of diabeticketoacidosis were selected.Results The study included 52 patients....

By Željka Dragila, Dora Rudić, Klara Ćosić, Tatjana Bačun