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Review paper

SARS-CoV-2 infection in adults and HIV: an update

By
Dimitrios Bousis ,
Dimitrios Bousis

Department of Internal Medicine, University General Hospital of Patras, Patras, Greece

Francesk Mulita Orcid logo ,
Francesk Mulita
Contact Francesk Mulita

Department of Surgery, University General Hospital of Patras, Patras, Greece

Ioanna Marlafeka ,
Ioanna Marlafeka

Department of Internal Medicine, University General Hospital of Patras, Patras, Greece

Themistoklis Paraskevas ,
Themistoklis Paraskevas

Department of Internal Medicine, University General Hospital of Patras, Patras, Greece

Dimitrios Velissaris
Dimitrios Velissaris

Department of Internal Medicine, University General Hospital of Patras, Patras, Greece

Abstract

Aim
COVID-19 pandemic caused by SARS-CoV-2 is spreading throughout the world affecting both healthy individuals and people with underlying immune-deficiencies. People living with human immunodeficiency virus (HIV) consist a group multiply affected by this universal crisis.
Methods
Literature search aiming to identify relevant publications referring to the consequences of the COVID-19 pandemic in
HIV infected population.
Results
A body of literature is rapidly growing in regard to epidemiological data, the interaction between HIV and SARS-CoV-2,
and clinical outcome in people living with HIV. Intensive research is warranted to identify any interactions of the co-existence of the two viruses in the immune system of HIV infected patients as common pathophysiology and molecular aspects are recognized. Human relations are diminished as a result of the social measures, and detailed recording of the consequences in this population is needed.
Conclusion
Further research could shed light on the common underlying molecular mechanisms of both conditions in an attempt to
discover treatment regimens for SARS-CoV-2 infection.

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