Vascular comorbidities in patients with multiple sclerosis and their impact on physical disability
Aim Given the impact of vascular comorbidities (VC) on the diagnosis, treatment, and outcome of multiple sclerosis (MS), weexamined the incidence and correlation of VC and risk factors for vascular disease in people with MS (PwMS) compared to the general population, and the impact on the physical disability of patients.Methods Cross-sectional study...
By Daliborka Tadić, Sanja Grgić, Aleksandra Dominović-Kovačević, Majda Nazalević-Bursać, Srđan Mavija, Vlado Đajić
Prognostic value of colour Doppler brain sonography for the neurodevelopmental outcome in term neonates with hypoxic ischaemic encephalopathy
Aim To determine a prognostic value of cerebral blood flow parameters for the development of neurological sequelae in term neonates with hypoxic ischaemic encephalopathy (HIE).Methods We reviewed medical records of 47 term neonates with HIE who survived until the age of 12 months of life. According tothe Sarnat and Sarnat clinical score, neonates w...
By Emina Hadžimuratović, Suada Branković, Admir Hadžimuratović, Melika Bukvić
Adherence to preventive behaviours and risk of COVID-19 infection: a case-control study
Aim To investigate the relationship between adherence to preventive behaviors and risk of COVID-19 infection.Methods In this case-control study, 491 participants were selected through convenience sampling. First, the samples of the casegroup (COVID-19 patients) were selected, and then the control group was matched with the case group based on age, ...
By Reza Hosseinabadi, Shoorangiz Biranvand, Khatereh Anbari
Regulation of p53 and survivin by Curcuma longa extract to caspase-3 dependent apoptosis in triple negative breast cancer cells
Aim Triple negative breast cancer cells (TNBC) are the population of breast cancer cells that are responsible for cancer recurrence and apoptosis resistance. Unfortunately, current therapies have limited efficacy to TNBC population due to apoptosis resistance and chemoresistance. Tumour suppressor p53 and survivin are primary targets for TNBC thera...
By Deryne Anggia Paramita, Dedy Hermansyah, Desiree Anggia Paramita, Nur Dina Amalina
A comparison of different doses of fentanyl for patients undergoing elective colonoscopy: a randomized double-blind clinical trial
Aim To investigate analgesic and side effects of different doses of fentanyl in combination with propofol for colonoscopy.Methods This prospective randomized double-blind study conducted between 2019 and 2020 included 64 patients. Patients were randomized: Group 1 (fentanyl 0.5 μg/kg) and Group 2 (fentanyl 1.0 μg/kg) both in combination with ...
By Mirza Kovačević, Adisa Šabanović Adilović, Nermina Rizvanović, Harun Adilović, Malik Ejubović, Alma Jahić Čampara
The effect of statin administration on IL-6 and IL-1b expression in peripheral blood mononuclear cells of a hypertensive patient with SARS-CoV-2 spike protein stimulation
Aim The infection of the SARS-CoV-2 virus potentially causes a cytokine storm with elevated IL-6 and IL-1β levels. Statin therapy was common among COVID-19 patients due to their cardiovascular comorbidities. However, the effect of statins on COVID-19 infection is unclear. The aim of this study was to evaluate the impact of statin administratio...
By Andrianto Andrianto, Budi Susetyo Pikir, Rizki Amalia, Teuku Yusriza, Fatimah Alzahra, Maya Qurota A’yun, Michael Jonatan
Sporadic chromosome translocation frequencies in lymphocyte cultures – a retrospective study in a cohort of patients from Bosnia and Herzegovina
Aim Chromosome translocations are considered as one of the most severe forms of genome defects. Because of the clinical significance of chromosome translocations and scarce data on the incidence of sporadic translocations in population of Bosnia and Herzegovina, we aimed to report sporadic translocation frequencies in samples karyotyped in our labo...
By Sanin Haverić, Anja Haverić, Maida Hadžić, Tamara Ćetković, Lejla Čaluk Klačar, Rifat Hadžiselimović
Interferon alpha and non-specific markers of inflammation in patients with systemic lupus erythematosus
Aim To determine the value of IFN (intzerferon)-α in the patients with systemic lupus erythematosus (SLE) and to correlate IFN-αwith values of non-specific biochemical parameters of inflammation (C-reactive protein, leukocytes values, erythrocyte sedimentation rate, albumins and globulins).Methods Research included 55 patients with SLE ...
By Lamija Zečević, Edin Begić, Buena Aziri, Izeta Aganović - Mušinović
Serum glucose, sodium and potassium concentrations in patients with diabetic ketoacidosis
Aim To investigate possible differences in serum glucose and sodium and potassium concentrations with respect to age, gender and severity of diabetic ketoacidosis.Methods Medical records from 1 January 2017 to 31 December 2019 were reviewed and patients with the diagnosis of diabeticketoacidosis were selected.Results The study included 52 patients....
By Željka Dragila, Dora Rudić, Klara Ćosić, Tatjana Bačun
Pregnancy outcomes of COVID-19 positive pregnant women at the Cantonal Hospital Zenica, Bosnia and Herzegovina
Aim To investigate clinical presentation of COVID-19 infection in pregnancy, its course during pregnancy, effects on pregnancyoutcomes for both mothers and newborns as well as the potential for vertical transmission.Methods This retrospective observational study included all identifi ed COVID-19-positive pregnant women admitted to the Cantonal Hosp...
By Jasmin Hodžić, Bedrana Muračević, Hana Štimjanin, Rasim Iriškić, Muamera Husika