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Review paper

Can laboratory and clinical parameters predict the occurrence of acute arterial occlusion in COVID-19 patients?

By
Kristian Karlović Orcid logo ,
Kristian Karlović
Contact Kristian Karlović

Department of Radiology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina

Gojko Bogdan ,
Gojko Bogdan

Department of Radiology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina

Pejana Rastović ,
Pejana Rastović

Department of Surgery, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina

Martin Kajić
Martin Kajić

Department of Surgery, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina

Abstract

Aim
To determine radiologic, clinic and laboratory characteristics of COVID-19 positive patients with acute arterial occlusion and compare them with post COVID-19 and non-COVID-19 patients.
Methods
In this retrospective study, 53 patients with acute occlusion of peripheral arteries admitted to the University Clinical
Hospital Mostar in the period between 29 February 2020 and 30 September 2021 were involved. The first group was made of COVID-19 positive patients, the second group were post COVID-19 patients and a control group were non-COVID-19 patients.
Results
Most patients were males, 37 (69.8%). The average age of COVID positive patients was 66.09±11.25 years, post COVID-19 patients 71.33±5.22 years and COVID-19 negative patients 69.82±1.99 years. Lower extremities were most affected, 38 (71.6%), without significant alteration in the coagulogram. Acute arterial occlusion occurred about 2 weeks after the beginning of COVID-19 or at the time of the first appearance of symptoms.
Conclusion
We have to take special care about patients with risk factors for developing acute arterial occlusion due to thromboembolism or thrombosis 10 days after the beginning of the disease. We also recommend the use of low molecular weight heparin
(LMWH) and monitoring coagulation state due to anti Xa and thromboelastometry.

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