Aim To assess trends in thrombolysis rates and door-to-needle times in University Hospital Mostar. Methods Data from the University Hospital Mostar Registry were used. Information on the number of ischaemic stroke patients, intravenous thrombolysis rates and „door-to-needle times“ (DNT) were collected between January 2013 and December 2021. Results Out of the total of 3100 ischaemic stroke patients, alteplase was given to 130 patients giving a thrombolysis rate of 4.2%. The mean hospital thrombolysis rate increased from 2.4% in 2013 to 10.6% in 2021. Conclusion Although the hospital thrombolysis rate more than quadrupled, there is still a low proportion of acute ischaemic stroke patients who received intravenous thrombolysis therapy. Education and interventions indicating the importance of recognition and treatment of acute ischemic stoke are necessary for all physicians.
Stroke rt PA-SSG. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995. p. 1581–7.
2.
Goyal M, Demchuk A, Menon B, Eesa M, Rempel J, Thornton J, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015. p. 1019–30.
3.
Berkhemer O, Fransen P, Beumer D, Van Den Berg L, Lingsma H, Yoo A, et al.
4.
N Engl J Med. 2015. p. 11–20.
5.
Collaborators G. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study. Lancet Neurol. 2019. p. 795–820.
6.
Feigin V, Lawes C, Bennett D, Barker-Collo S, Parag V. Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review. Lancet Neurol. 2009. p. 355–69.
7.
Kim J, Thayabaranathan T, Donnan G, Howard G, Howard V, Rothwell P, et al. Global stroke statistics. Int J Stroke. 2019. p. 819–22.
8.
Yaria J, Gil A, Makanjuola A, Oguntoye R, Miranda J, Lazo-Porras M, et al. Quality of stroke guidelines in low-and middle-income countries: a systematic review. Bull World Health Organ. 2021. p. 640–52.
9.
Krawczyk P, Swiecicki L. ICD-11 vs. ICD-10 -a review of updates and novelties introduced in the latest version of the WHO International Classification of Diseases. Psychiatr Pol. 2020. p. 7–20.
10.
Mikulik R, Bar M, Cernik D, Herzig R, Jura R, Jurak L, et al. Stroke 20 20: Implementation goals for intravenous thrombolysis. Eur Stroke J. 2021. p. 151–9.
11.
Nilanont Y, Nidhinandana S, Suwanwela N, Hanchaiphiboolkul S, Pimpak T, Tatsanavivat P, et al. Quality of acute ischemic stroke care in Thailand: a prospective multicenter countrywide cohort study. J Stroke Cerebrovasc Dis. 2014. p. 213–9.
12.
Zakaria M, Aref H, Elnasser A, Fahmy A, Tork N, Fouad M, et al. Egyptian experience in increasing utilization of reperfusion therapies in acute ischemic stroke. Int J Stroke. 2018. p. 525–9.
13.
Phan H, Gall S, Blizzard C, Lannin N, Thrift A, Anderson C, et al. Sex Differences in Care and Long-Term Mortality After Stroke: Australian Stroke Clinical Registry. J Womens Health (Larchmt). 2019. p. 712–20.
14.
Willeit J, Geley T, Schoch J, Rinner H, Tur A, Kreuzer H, et al. Thrombolysis and clinical outcome in patients with stroke after implementation of the Tyrol Stroke Pathway: a retrospective observational study. Lancet Neurol. 2015. p. 48–56.
15.
Norrving B, Barrick J, Davalos A, Dichgans M, Cordonnier C, Guekht A, et al. Action Plan for Stroke in Europe 2018-2030. Eur Stroke J. 2018. p. 309–36.
16.
Powers W, Rabinstein A, Ackerson T, Adeoye O, Bambakidis N, Becker K, et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the. Stroke. American Heart Association/American Stroke Association; 2018. p. 46-e110.
17.
Kuhrij L, Wouters M, Van Den Berg-Vos R, De Leeuw F, Nederkoorn P. The Dutch Acute Stroke Audit: Benchmarking acute stroke care in the Netherlands. Eur Stroke J. 2018. p. 361–8.
18.
Collaborators G. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study. Lancet. 2017. p. 1684–735.
19.
Li L, Scott C, Rothwell P. Oxford Vascular S. Trends in stroke incidence in high-income countries in the 21st century: population-based study and systematic review. Stroke. 2020. p. 1372–80.
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