Original article

Analysis of Interleukin 8 (IL-8) Levels, Blood Urea Nitrogen/Albumin Ratio, Pneumonia Severity Index, and Length of Stay in Patients Undergoing Pulmonary Rehabilitation and Shortwave Diathermy

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Abstract

Objective: This study aims to analyze the effects of Pulmonary Rehabilitation (PR) and short-wave Diathermy (SWD) on the Blood Urea Nitrogen (BUN)/Albumin ratio, Pneumonia Severity Index (PSI), IL-8 levels, and length of stay (LOS) in hospitalized pneumonia patients.

Material: and method: This is a randomized experimental study with a pre-post control group structure. The study included 24 pneumonia patients who were treated at Dr. Saiful Anwar General Hospital and Lawang General Hospital between 2022 and 2023. For 5 days, subjects were separated into three groups: control, intervention (PR only), and intervention (PR and SWD). The data were examined by comparing the deltas of each group. PSI and CURB-65 were used to calculate severity indices and blood samples were obtained before and after the intervention to determine the BUN/Albumin ratio and IL-8 levels.

Results: There was a significant decrease in the BUN/Albumin ratio after the intervention (p=0.03). IL-8 levels and LOS showed a decreasing trend, although not statistically significant (p=0.208; p=0.249). There was a substantial correlation between PSI and IL-8 and the BUN/Albumin ratio (p=0.015; p=0.002; p=0.001).

Conclusion: This study highlights reduced IL-8 levels, the BUN/Albumin ratio, and a shorter LOS in pneumonia patients receiving PR and SWD therapy for 5 days. This study reinforces the evidence that PR and SWD can serve as adjunctive therapies for patients with pneumonia.

Keywords: BUN/Albumin ratio, pneumonia, interleukin-8 (IL-8), pulmonary rehabilitation, and shortwave diathermy.

How to Cite:

Primaputri, C. C., R. Sugiri, Y. J., Chozin, I. N., Listyoko, A. S., Wati, Y. E. & Rahmad, R., (2025) “Analysis of Interleukin 8 (IL-8) Levels, Blood Urea Nitrogen/Albumin Ratio, Pneumonia Severity Index, and Length of Stay in Patients Undergoing Pulmonary Rehabilitation and Shortwave Diathermy”, Medicinski glasnik 22(2), 212-217. doi: https://doi.org/10.17392/1949-22-02