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Original article

Association of triglyceride glucose index as insulin resistance measure and waist to hip ratio in apparently healthy students of University of Sarajevo

Authors
  • Sabaheta Hasić orcid logo (University of Sarajevo, Sarajevo, Bosnia and Herzegovina)
  • Aida Đozo orcid logo (Department for Blood-Borne Disease Testing, Blood Transfusion Institute of the Federation of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina)
  • Emina Kiseljaković orcid logo (University of Sarajevo, Sarajevo, Faculty of Medicine, Department of Medical Biochemistry, Bosnia and Herzegovina)
  • Radivoj Jadrić orcid logo (University of Sarajevo, Sarajevo, Faculty of Medicine, Department of Medical Biochemistry, Bosnia and Herzegovina)
  • Lamija Mlaćo orcid logo (University of Sarajevo, Sarajevo, Faculty of Medicine, Department of Human Physiology, Bosnia and Herzegovina)
  • Amil Topuz orcid logo (University of Sarajevo, Sarajevo, Faculty of Medicine, Department of Medical Biochemistry, Bosnia and Herzegovina)
  • Selma Hasić orcid logo (University Clinical Centre Sarajevo, Sarajevo, Clinical Pathology and Cytology, Bosnia and Herzegovina)

Abstract

Aim: This study aimed to reveal the prevalence of the insulin resistance (IR) identified by triglyceride glucose index (TyG index) among students of University of Sarajevo. The impact of visceral fat level and waist to hip ratio measures on TyG value in students has been investigated. Patients and methods. Study included 160 apparently healthy students, both genders, aged from 19-27 years. Two groups were formed: Group1, TyG <4,49 and Group 2, TyG³4,49. A short interview, questionnaire, anthropometric measures, visceral fat level (VFL), blood pressure and biochemical parameters were applied. The statistical level of significance was P<0,05.

Results: . Forty-five students (28, 1%) were insulin resistant. There was a significant difference in TyG value (P<0,001), [group 1- 4,19 (3,93-4,34 vs. group 2 - 4,59 (4,55-4,74)]. Fasting blood glucose (FBG) and lipid parameters-total cholesterol, triglycerides and very low-density lipoprotein cholesterol (TC, TG and VLDL-C) were significantly higher in group TyG ³4,49 compared to TyG <4,49 group, with exception of HDL-C of LDL-C (P>0.05). Stepwise linear regression analysis showed significant impact of waist to hip ratio on TyG value (P=0,001).

Conclusion: The prevalence of IR measured by TyG in university students was 28,1%. The impact of waist to hip ratio on value of TyG index points on possible application of both parameters in visceral obesity and insulin resistance assessment in apparently healthy individuals.

Keywords: blood glucose, triglycerides, obesity, prevalence

How to Cite:

Hasić, S., Đozo, A., Kiseljaković, E., Jadrić, R., Mlaćo, L., Topuz, A. & Hasić, S., (2025) “Association of triglyceride glucose index as insulin resistance measure and waist to hip ratio in apparently healthy students of University of Sarajevo”, Medicinski glasnik 22(2), 248-252. doi: https://doi.org/10.17392/1978-22-02

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Published on
2025-08-25

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CC-BY-NC-ND 4.0