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Original article

A rare case of high-grade synovial sarcoma of the hindfoot

Authors
  • Chiara Comisi (Agostino Gemelli University Polyclinic, Rome, Italy)
  • Tommaso Greco (Agostino Gemelli University Polyclinic, Rome, Department of Aging, Orthopaedic and Rheumatologic Sciences, Orthopaedics and Trauma Surgery Unit, Italy)
  • Camillo Fulchignoni (Agostino Gemelli University Polyclinic, Rome, Italy)
  • Antonio Mascio (Agostino Gemelli University Polyclinic, Rome, Italy)
  • Francesco Farine (Agostino Gemelli University Polyclinic, Rome, Italy)
  • Elisa Troiano (University of Siena, Siena, Italy)
  • Nicola Mondanelli (University of Siena, Siena, Italy)
  • Giulio Menichini (Azienda Ospedaliero-Universitaria Careggi, Florence, Plastic and Reconstructive Microsurgery , Italy)
  • Elisabetta Pataia (Agostino Gemelli University Polyclinic, Rome, Italy)
  • Giulio Maccauro (Agostino Gemelli University Polyclinic, Rome, Italy)
  • Carlo Perisano (Agostino Gemelli University Polyclinic, Rome, Italy)

Abstract

Aim: To report our personal experience in hindfoot reconstruction using an anterolateral thigh (ALT) free flap following radical resection of a high-grade synovial sarcoma.

Methods: The patient underwent clinical and imaging assessments, and a biopsy of the lesion confirmed the diagnosis of synovial sarcoma (SS) of the hindfoot. A multidisciplinary team was involved to define the most appropriate therapeutic strategy.

Results: After radical resection of the tumor mass, soft tissue coverage of the extensive skin defect was achieved using an ALT free flap. No local recurrences were observed during the follow-up period. At ap proximately twenty-four months after surgical treatment, the patient is able to ambulate independently, with no significant limitations in daily activities.

Conclusion: The complex management of this rare disease requires a dedicated reference centre for foot and ankle surgery, supported by a multidisciplinary team including expert orthopaedic and plastic surgeons, as well as specialized oncologists, to ensure accurate diagnosis and appropriate treatment. Key words: flap, foot, limb salvage, reconstructive surgical procedures, soft tissue sarcoma

Keywords: flap, Foot, limb salvage, Reconstructive Surgical Procedures, Soft Tissue Sarcoma.

How to Cite:

Comisi, C., Greco, T., Fulchignoni, C., Mascio, A., Farine, F., Troiano, E., Mondanelli, N., Menichini, G., Pataia, E., Maccauro, G. & Perisano, C., (2025) “A rare case of high-grade synovial sarcoma of the hindfoot”, Medicinski glasnik 22(2), 344-349. doi: https://doi.org/10.17392/1967-22-02

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Published on
2025-08-25

Peer Reviewed

License

CC-BY-NC-ND 4.0