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Original article

Chest x-ray resolution after SARS-CoV-2 infection

Authors
  • Besim Prnjavorac orcid logo (General Hospital Tešanj; School of Medicine, University of Zenica; Sarajevo School of Science and Technology; Faculty of Pharmacy, University of Sarajevo)
  • Aida Mujaković (Sarajevo School of Science and Technology; General Hospital “Prim.dr Abdulah Nakaš“ Sarajevo)
  • Lejla Prnjavorac (General Hospital Tešanj, Tešanj, Bosnia and Herzegovina)
  • Tamer Bego (Faculty of Pharmacy, University of Sarajevo)
  • Edin Jusufović (School of Medicine, University of Tuzla; Health and Educational Medical Center for Pulmonary Diseases)
  • Edin Begić (Sarajevo School of Science and Technology; General Hospital “Prim.dr Abdulah Nakaš“ Sarajevo)
  • Vildana Torlak-Arnaut (School of Medicine, University of Zenica; Cantonal Hospital Zenica)
  • Mutapčić Meliha (School of Medicine, University of Zenica; Cantonal Hospital Zenica)
  • Hasan Škiljo (General Hospital Tešanj; School of Medicine, University of Zenica)
  • Enes Hodžić (General Hospital Tešanj; School of Medicine, University of Zenica)
  • Emina Karahmet (Faculty of Pharmacy, University of Sarajevo)
  • Maja Malenica (Faculty of Pharmacy, University of Sarajevo)
  • Tanja Dujić (Faculty of Pharmacy, University of Sarajevo)
  • Jusuf Mehić (General Hospital Tešanj)
  • Nedžada Irejiz (General Hospital Tešanj)
  • Rifat Sejdinović (General Hospital Tešanj; School of Medicine, University of Zenica)
  • Anel Mahmutović (General Hospital Tešanj)
  • Ajdin Ibrahimović (General Hospital Tešanj)

Abstract

Aim To analyse the resolution of chest X-ray findings in relation to laboratory parameters in patients infected with acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a two- month follow-up. Analysis of chest X-ray findings in the first few months after the disease is the main goal of our work. Methods Out of the total of 343 patients chest X-ray findings were followed in 269 patients. Patients were divided into groups according to the severity of findings. D-dimer, inflammatory markers, blood cell count, neutrophil lymphocyte ratio (NLR) were analysed. Chest X-ray was analysed during the hospitalization on the day of admission, on the third, the seventh and the fourteenth day (scoring method was used). After discharge chest X-ray was performed in a two-week follow-up, then after one and two months, and after three months if necessary. Results Incomplete chest X-ray resolution was identified in 24 (39.34%) patients with severe, 27 (22.31 %) patients with moderate and in three (3.91%) patients with mild findings. Statistical significance was established in overall score by comparison between all groups (p<0.001), and in the moderate compared to the mild group (p=0.0051). The difference of NLR in the severe compared to the moderate group was observed (p=0.0021) and in the severe group compared to the mild group (p=0.00013). Conclusion Chest X-ray findings persisted mostly in the severe group followed by the moderate and mild ones. Long-term follow-up is necessary for the appropriate treatment and prevention of fibrosis, and reduction of symptoms.

Keywords: COVID-19, fibrosis, inflammation, lung

How to Cite:

Prnjavorac, B., Mujaković, A., Prnjavorac, L., Bego, T., Jusufović, E., Begić, E., Torlak-Arnaut, V., Meliha, M., Škiljo, H., Hodžić, E., Karahmet, E., Malenica, M., Dujić, T., Mehić, J., Irejiz, N., Sejdinović, R., Mahmutović, A. & Ibrahimović, A., (2021) “Chest x-ray resolution after SARS-CoV-2 infection”, Medicinski glasnik 18(2), 370-377. doi: https://doi.org/10.17392/1391-21

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Published on
2021-01-01

Peer Reviewed

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CC-BY-NC-ND 4.0