Aim To identify clinical and laboratory parameters on admission and/or during a hospital stay that would predict prolonged hospital stay in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods A retrospective cross-sectional study was conducted at the Clinic for Pulmonary Diseases and Tuberculosis, Clinical Cen...

By Aida Mujaković, Belma Paralija, Besim Prnjavorac, Orhan Lepara, Almir Fajkić, Edin Begić, Avdo Kurtović, Midhat Čizmić, Mirad Odobašić

Aim To investigate influence of neutrophil-to-lymphocyte ratio (NLR) and proatherogenic risk factors to improve the accuracyof pneumonia severity index (PSI) in the prediction of community acquired pneumonia (CAP) outcome in healthy individuals.Methods A retrospective observational cross-sectional study conducted at the Clinic for Pulmonary Disease...

By Aida Mujaković, Belma Paralija, Orhan Lepara, Almir Fajkić, Avdo Kurtović, Besim Prnjavorac, Edin Begić, Nejra Gondžetović - Ćorić

Aim To analyse the resolution of chest X-ray findings in relation to laboratory parameters in patients infected with acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a two- month followup. Analysis of chest X-ray findings in the first few months after the disease is the main goal of our work.Methods Out of the total of 343 patients chest X-...

By Enes Hodžić, Ajdin Ibrahimović, Anel Mahmutović, Rifat Sejdinović, Nedžada Irejiz, Jusuf Mehić, Tanja Dujić, Maja Malenica, Emina Karahmet, Besim Prnjavorac, Hasan Škiljo, Mutapčić Meliha, Vildana Torlak-Arnaut, Edin Begić, Edin Jusufović, Tamer Bego, Lejla Prnjavorac, Aida Mujaković

Aim To investigate interleukin 6 (IL-6) values depending on duration of diabetes mellitus (DM) and evaluate possible correlationwith diabetic polyneuropathy.Methods The research study included 90 patients with DM divided into three groups (30 patients each) according to the durationof DM: group A – patients who had DM for less than 10 years, ...

By Emina Karahmet, Besim Prnjavorac, Tamer Bego, Adaleta Softić, Lejla Begić, Edin Begić, Esma Karahmet, Lejla Prnjavorac, Irfan Prnjavorac

Aim To investigate the usage of chest computed tomography (CT) scan score for improvement in diagnostic and treatment efficacy of repetitive pleural effusion. MethodsCT scan scoring system was used as a part of diagnostic procedures in patients with repetitive pleural effusion. Patients with at least two pleurocentesis were included in the study. C...

By Lejla Burnazović-Ristić, Besim Prnjavorac, Tamer Bego, Maida Rakanović-Todić, Lejla Prnjavorac

Aim To investigate predictive value of procalcitonin in diagnosis of sepsis in predicting positive blood culture, and possibility to predict final outcome in septic patients. Method This prospective study involved 106 hospitalized patients who met two or more criteria for systemic inflammatory response syndrome (SIRS). In comparison to Sepsis Relat...

By Sehveta Mustafić, Selmira Brkić, Besim Prnjavorac, Albina Sinanović, Humera Porobić-Jahić, Sabina Salkić

Aim To analyse frequency of chronic obstructive pulmonary disease (COPD) exacerbation in patients on therapy with inhaled corticosteroids (ICS) and relevant factors that influence the rate of COPD exacerbations in a subgroup of moderate illness, like FEV1, comorbidities and other concomitant therapy. Methods The study included patients with moderat...

By Maida Rakanović-Todić, Sanita Maleškić, Lejla Burnazović Ristić, Aida Kulo Ćesić, Jasna Kusturica, Besim Prnjavorac

Aim To investigate whether or not additional treatment of ischemic heart disease with trimetazidine could improve effort tolerance and overall quality of life of patients with ischemic heart disease. Methods The study included 200 patients with ischemic heart disease. The sample was divided into 2 randomly selected groups: experimental and control ...

By Una Suljić, Besim Prnjavorac, Tamer Bego, Maja Malenica, Tanja Dujić, Irfan Prnjavorac, Adlija Čaušević, Lejla Šaranović

Aim To analyse the long-term impact of altered metabolism on the level of mediators of inflammatory response in female patients with type 2 diabetes. Methods This study included 97 female patients with type 2 diabetes and 107 female, nondiabetic control subjects, who were recruited at the Clinical Centre University of Sarajevo and the General Hospi...

By Maja Malenica, Mira Šilar, Tanja Dujić, Tamer Bego, Sabina Semiz, Selma Škrbo, Besim Prnjavorac, Adlija Čaušević

Aim To investigate association of two LPIN1 gene variations with main traits of metabolic syndrome (MS) (waist circumference,body mass index, blood pressure, triglycerides, HDL-cholesterol and fasting glucose levels) in population from Bosnia and Herzegovina.Methods This study included 43 patients with metabolic syndrome and 43 healthy controls fro...

By Tamer Bego, Tanja Dujić, Barbara Mlinar, Sabina Semiz, Maja Malenica, Besim Prnjavorac, Barbara Ostanek, Janja Marc, Anida Čaušević-Ramoševac, Adlija Čaušević