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Review paper
Received: 07.07.2022. >> Accepted: 30.08.2022. >> Published: 01.12.2022. Biochemistry
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https://doi.org/10.17392/1514-22

Parameters in predicting the risk of a prolonged hospital stay in patients with acute exacerbation of chronic obstructive pulmonary disease: a single-centre experience

By
Aida Mujaković Orcid logo ,
Aida Mujaković
Contact Aida Mujaković

Department of Pulmonology, General Hospital “Prim. dr. Abdulah Nakaš“, Sarajevo, Bosnia and Herzegovina

Department of Pathophysiology, School of Medicine, Sarajevo School of Science and Technology, Sarajevo, Bosnia and Herzegovina

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Belma Paralija ,
Belma Paralija

Clinic for Pulmonary Diseases and Tuberculosis “Podhrastovi”, University of Sarajevo Clinical Centre, Sarajevo, Bosnia and Herzegovina

Department of Internal Medicine, School of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

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Besim Prnjavorac ,
Besim Prnjavorac

Department of Pathophysiology, School of Medicine, Sarajevo School of Science and Technology, Sarajevo, Bosnia and Herzegovina

Department of Pulmonology, General Hospital Tešanj, Tešanj, Bosnia and Herzegovina

Department of Pathophysiology, School of Medicine, University of Zenica, Zenica, Bosnia and Herzegovina

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Orhan Lepara ,
Orhan Lepara

Department of Physiology, School of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

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Almir Fajkić ,
Almir Fajkić

Department of Pathophysiology, School of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

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Edin Begić ,
Edin Begić

Department of Cardiology, General Hospital “Prim.dr Abdulah Nakaš“, Sarajevo, Bosnia and Herzegovina

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Avdo Kurtović ,
Avdo Kurtović

Primary Healthcare Centre Gračanica, Gračanica, Bosnia and Herzegovina

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Midhat Čizmić ,
Midhat Čizmić

Department of Radiology, General Hospital “Prim. dr Abdulah Nakaš“, Sarajevo, Bosnia and Herzegovina

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Mirad Odobašić
Mirad Odobašić

Private Healthcare Institution „Poliklinika dr. Odobašić“, Sarajevo, Bosnia and Herzegovina

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Abstract

Aim
To identify clinical and laboratory parameters on admission and/or during a hospital stay that would predict prolonged hospital stay in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).
Methods
A retrospective cross-sectional study was conducted at the Clinic for Pulmonary Diseases and Tuberculosis, Clinical Centre University of Sarajevo for the period 2019-2021 accounting patients admitted due to AECOPD. The need for hospitalization was evaluated according to the current GOLD criteria and certain clinical parameters. Spirometry testing and laboratory analysis were performed for all patients on the day of admission and on the 10th day of hospital stay. Linear regression was used to show the relationship between multiple independent predictor variables
and LOS.
Results
A total of 50 patients were evaluated during their hospital stay due to AECOPD. Median of LOS was 22.02±1.06, with 90%
hospital survival rate. Due to AECOPD the median of LOS in the intensive care unit (ICU) was 4±0.68 days with pH<7.35 in 34% of hospitalized patients. According to spirometry classification on the day of admission, 56% of patients were assigned to group 3 and 16% to group 4 with significant improvement identified on spirometry findings on discharge. Platelets on the day of admission were the only statistically significant positive predictors of the length of hospital stay.
Conclusion
Identifying chronic obstructive pulmonary disease patients at risk of frequent exacerbations and appropriate disease
management could reduce the disease burden.

Keywords:

chronic obstructive pulmonary disease,
hospitalization,
therapeutics

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