Functional gastrointestinal disorders in children: a single centre experience
Functional gastrointestinal disorders in childhood (FGIDs) constitute a significant time-consuming clinical problem for healthcare practitioners, and they carry an important psychosocial burden for patients and their families. The aim of this study was to characterize etiology, clinical features, and interventions in a paediatric cohort of patients...
By Amela Selimović, Nina Mekić, Selma Terzić, Almira Ćosićkić, Evlijana Zulić, Majda Mehmedović
Availability and quality of primary health care in the compulsory health insurance system in Kazakhstan
Aim To evaluate patient satisfaction with primary healthcare services and determine effectiveness indicators within Kazakhstan's compulsory health insurance system.Methods An analytical observational study with cross-examination was conducted in Kazakhstan's primary healthcare (PHC) organizations. Patient satisfaction was assessed through a 35-item...
By Makhabbat Shurenova, Kuralbay Kurakbayev, Tleukhan Abildaev, Aigul Tazhiyeva
Prevalence of familial hypercholesterolemia in patients with acute coronary syndrome
Aim To investigate the prevalence of familial hypercholesterolemia in patients with acute coronary syndrome (ACS).Methods The study included fifteen patients with first or repeated ACS and treated/nontreated dyslipidaemia admitted to the Department of Cardiovascular Diseases of Clinical Hospital Centre Osijek between 1 January 2020 and 1 January 20...
By Željka Dragila, Matea Lozert, Silvija Canecki-Varžić, Kristina Selthofer-Relatić
Hypoxic mesenchymal stem cells (MSCS)-induced interleukin (IL)-10 alleviate systemic lupus erythematosus (SLE) infl ammation through inhibiting interferon (IFN)-gamma production
Aim To determine the eff ect of hypoxic mesenchymal stem cells (MSCs) on the interleukin (IL)-10 and interferon (IFN)-gamma in peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients.Methods This study used a post-test control group design. Hypoxic MSCs were isolated and characterized according to their surface m...
By Yan Wisnu Prajoko, Agung Putra, Ardi Prasetio, Nur Dina Amalina
Prediction of pulmonary embolism and its complication in diabetes mellitus type 2: a 5-year retrospective study
Aim To investigate the association between type 2 diabetes mellitus (T2DM) and pulmonary embolism, as well as to determine the prognostic value of troponin, D-dimer, prothrombotic, and proinflammatory markers in patients with T2DM.Methods The retrospective cohort study included 305 patients with pulmonary embolism, divided into two groups: the firs...
By Jasmina Bošnjić
Comparison of cutout risk factors between single- and doublescrew proximal nails in intertrochanteric femur fractures - a multicentric study
Aim Significant risk factors for femoral nail cutout are well-documented, primarily in the context of single-screw proximal nails.However, it remains uncertain whether those same risk factors are applicable when considering different implant devices. The aim of this retrospective cohort study was to compare cutout risk factors between single- versu...
By Michele Coviello, Antonella Abate, Giovanni Vicenti, Francesco Ippolito, Vittorio Nappi, Andrea Michele Abbaticchio, Elio Caiaffa, Giulia Colasuonno, Vincenzo Caiaffa, Giuseppe Solarino
Platelet rich plasma (PRP) in the surgical treatment of Haglund’s syndrome: the use of PRP membranes as an intra-operative local adjuvant
Aim Haglund's syndrome may be responsible for chronic pain in the ankle and hindfoot. Although numerous therapeutic approaches have been described in the literature, to this date no consensus over a surgical treatment has been established. We report our experience in the treatment of Haglund's syndrome and pre-insertional calcifications of the Achi...
By Giuseppe Restuccia, Giorgio Varchetta, Alessandro Lippi, Lorenzo Dolfi, Federico Bizzocchi, Stefano Giovannetti, Edoardo Ipponi
An impact of treatment initiation timing on stroke outcome: bridging the time gap
Aim Stroke treatment is a time-critical condition. Understanding the impact of timing and types of treatment on patient outcomes can help develop and optimize stroke management strategies. The study aimed to analyse the effect of different time intervals and mechanical thrombectomy methods on outcomes of stroke patients in Kazakhstan.Methods The pa...
By Kuanysh Nikatov, Ermek Dyussembekov, Rauan Kastey, Yevgeniy Zhukov, Niyazbek Yerniyazov, Mukhtar Korabayev, Gani Akhanov, Timur Saliev, Ildar Fakhradiyev
ChatGPT's contributions to the evolution of neurosurgical practice and education: a systematic review of benefits, concerns and limitations
Aim This study provides a comprehensive review of the current literature on the use of ChatGPT, a generative Artificial Intelligence (AI) tool, in neurosurgery. The study examines potential benefits and limitations of ChatGPT in neurosurgical practice and education.Methods The study involved a systematic review of the current literature on the use ...
By Hakija Bečulić, Emir Begagić, Rasim Skomorac, Anes Mašović, Edin Selimović, Mirza Pojskić
The ion resonance and bromelain-vitamin C vs bromelainvitamin C to prevent ankle complications in post-operative bimalleolar surgery
Aim To investigate whether the use of ion resonance and bromelain-vitamin C or bromelain-vitamin C is the best to prevent ankle complications in post operative bimalleolar surgery.Methods A total of 61 patients treated with bimalleolar surgery were enrolled. The patients were divided into three groups: thefirst group (n=22) treated only with the su...
By Luigi Meccariello, Anna Iolanda Bello, Giovanni Bove, Nicola Gagliardo, D’Anna Raffaele, Luigi Matera