Aim To investigate association of two LPIN1 gene variations with main traits of metabolic syndrome (MS) (waist circumference,body mass index, blood pressure, triglycerides, HDL-cholesterol and fasting glucose levels) in population from Bosnia and Herzegovina.Methods This study included 43 patients with metabolic syndrome and 43 healthy controls fro...

By Tamer Bego, Tanja Dujić, Barbara Mlinar, Sabina Semiz, Maja Malenica, Besim Prnjavorac, Barbara Ostanek, Janja Marc, Anida Čaušević-Ramoševac, Adlija Čaušević

Aim To evaluate the effect of perioperative statin treatment on postoperative atrial fibrillation and cardiac mortality in patients undergoing coronary artery bypass grafting.Methods A total of 1890 patients who underwent isolated coronary artery bypass were analyzed retrospectively, of which 425patients (22.4%) older than 70 were included in the s...

By Ayşegül Kunt, Sedat Özcan, Aslihan Küçüker, Dolunay Odabaşi, Alper Sami Kunt

Aim To investigate the frequency of different cord care practices as well recommendations to parents on cord care, along with the need to identify as well as reach the consensus on best cord care practices and other procedures in newborn care among health workers.Methods The study was conducted among 110 health care workers at the nursery departmen...

By Sanja Kanisek, Nada Prlić, Ivana Barać, Lorna Dubac Nemet

Aim To investigate the relationship of IL-1β and IL-6 cytokine gene polymorphisms with obstructive sleep apnea syndrome(OSAS) in 61 patients admitted to the neurology clinic in Kafkas University Hospital with insomnia problem who were diagnosed with OSAS in sleeping labs, and 80 healthy subjects not associated with the syndrome.MethodsBlood sa...

By Ilhami Gok, Nergiz Huseyinoglu, Dogan Ilhan

Aim To evaluate the usefulness of echocardiography in the diagnosis of complete rupture of papillary muscle.Methods Transthoracic (TTE) and transesophageal echocardiography (TEE) was performed with the ATL 3000 HDI UltrasoundInc (Bothell, WA, USA) with a 2.5 MHz transducer and 5-7 MHz multiplane phased array transducer. We are reporting about two p...

By Josip Vincelj, Stanko Biočić, Mario Udovičić, Mario Sičaja, Sandra Jakšić Jurinjak

Aim To determine an influence of alpha-lipoic acid to reduction of body weight and regulation of total cholesterol concentration,triglycerides and glucose serum levels in obese patients with diabetes mellitus type 2.Methods A prospective study includes two groups of obese patients with diabetes mellitus and signs of peripheral polyneuropathia: exam...

By Azra Okanović, Besim Prnjavorac, Edin Jusufović, Rifat Sejdinović

Aim To analyse clinical, laboratory and epidemiological characteristics of brucellosis in children in Bosnia and Herzegovina.Methods The study included 246 children aged 0-18 years, who were hospitalized in Clinics and Departments for Infectious Diseases in Tuzla, Sarajevo, Banja Luka, Zenica and Bihać in the period 2000-2013, in whom the diagnosis...

By Sead Ahmetagić, Humera Porobić-Jahić, Nada Koluder, Lejla Čalkić, Snježana Mehanić, Eldira Hadžić, Nevzeta Ibrahimpašić, Svjetlana Grgić, Mirela Zirić, Jelena Bajić, Denis Žepić

Aim To assess serum levels and correlation between uric acid (UA) and C-reactive protein (CRP) in acute coronary syndrome(ACS) and apparently healthy individuals.Methods The cross-sectional study included 116 examinees of age 44 to 83 years, distributed in two groups: 80 ACS patientsincluding 40 with acute myocardial infarction (AMI), and 40 with u...

By Emina Spahić, Sabaheta Hasić, Emina Kiseljaković, Halima Resić, Mehmed Kulić

Aim To compare efficacy and toxicity of bolus application of chemotherapy protocol, oxaliplatin, fluorouracil (bolus), leucovorin(folfox) between two groups of patients in the therapy of metastatic colorectal carcinoma (mCRC).Methods A total of 63 patients were treated for mCRC in the period January 2009 – January 2010 at the Department of On...

By Ibrahim Šišić, Belma Pojskić, Alma Mekić-Abazović, Vladimir Kovčin

Aim To investigate the characteristics of meticillin-resistant S. aureus (MRSA), extended-spectrum (ESBL), and plasmid-mediated AmpC beta-lactamase producing Gram-negative bacteria causing skin and soft tissue infections (SSTIs) in hospital and outpatient settings of Zenica-Doboj Canton, Bosnia and Herzegovina.Methods Antibiotic susceptibility was ...

By Selma Uzunović, Branka Bedenić, Ana Budimir, Amir Ibrahimagić, Farah Kamberović, Zlatko Fiolić, Michelle I. A. Rijnders, Ellen E. Stobberingh