Department of Physical Medicine and Rehabilitation, Abant Izzet Baysal University Medical Faculty, Turkey
Department of Cardiology, Koroglu Training and Research Hospital, Turkey
Department of Cardiology, Abant Izzet Baysal University Medical Faculty, Bolu, Turkey
Department of Cardiology, Abant Izzet Baysal University Medical Faculty, Bolu, Turkey
Department of Physical Medicine and Rehabilitation, Abant Izzet Baysal University Medical Faculty, Bolu, Turkey
Department of Physical Medicine and Rehabilitation, Abant Izzet Baysal University Medical Faculty, Bolu, Turkey
Department of Physical Therapy and Rehabilitation, Karabuk University Medical Faculty, Karabuk, Turkey
Physical Therapy and Rehabilitation of Department, Aksaray State Hospital, Aksaray, Turkey
Aim
To investigate whether there is a relation between neutrophillymphocyte (N/L) and platelet- lymphocyte (P/L) ratios and epicardial adipose tissue (EAT) thickness in patients with ankylosing spondylitis (AS).
Methods
Thirty patients diagnosed with ankylosing spondylitis and 25 healthy people (controls) were included in the study. Age,
gender, body mass index (BMI), height, hemogram, sedimentation, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, CRP, hepatic and renal function tests, lipid profile of the all patients were recorded. Data related to duration of the disease, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) values of the cases in the patient group were obtained. A cardiologist measured EAT thickness by ECHO in both patient and control groups.
Results
In the patient group, mean BASDAI and BASFI scores were 2.48±2.21 and 1.5±2.07, respectively. Age, gender, BMI values did not show statistically significant difference between the patient and the control groups. N/L and P/L ratios did not change significantly in the patient group having higher EAT, BASFI values and taking anti-TNF compared to the control group.
Conclusion
In patients with AS, EAT measurements, which are related to inflammatory response increase, can be used for monitoring of the risk of development of cardiac disease. We could not find the relation between EAT and N/L, P/L ratios in terms of
evaluation of inflammatory response.
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