Aim To evaluate possibilities of computed tomography (CT) perfusion in differentiation of solitary focal liver lesions based ontheir characteristic vascularization through perfusion parameters analysis.Methods Prospective study was conducted on 50 patients in the period 2009-2012. Patients were divided in two groups: benignand malignant lesions. Th...

By Irmina Sefić Pašić, Anes Pašić, Spomenka Kristić, Adnan Beganović, Aladin Čarovac, Amra Dzananovic, Lidija Lincender, Sandra Vegar Zubović

Aim To analyse clinical, laboratory and epidemiological characteristics of brucellosis in children in Bosnia and Herzegovina.Methods The study included 246 children aged 0-18 years, who were hospitalized in Clinics and Departments for Infectious Diseases in Tuzla, Sarajevo, Banja Luka, Zenica and Bihać in the period 2000-2013, in whom the diagnosis...

By Sead Ahmetagić, Humera Porobić-Jahić, Nada Koluder, Lejla Čalkić, Snježana Mehanić, Eldira Hadžić, Nevzeta Ibrahimpašić, Svjetlana Grgić, Mirela Zirić, Jelena Bajić, Denis Žepić

Aim Autoimmune thyroid disease (AITD) is a multifactorial disease with a genetic predisposition. The protein tyrosine phosphatase-22 (PTPN-22) gene is a powerful inhibitor of T-cell activation. The aim of this study was to compare messenger RNA (mRNA) PTPN22 expression between healthy persons and patients with hypothyroidism and with their affected...

By Gabriel Conzuelo Rodríguez, Hugo Mendieta Zerón

Aim Despite many studies published in recent years concerning the relationship between demographic factors and varicocele, this issue remains controversial. The aim of this study was to identify a possible influence of body mass index (BMI) and height on occurrence varicocele in men.Methods In a case-control study 153 patients aged 18-40 years from...

By Hamid Shafi, Mouloud Agajani Delavar

Aim To report the incidence of endophthalmitis following the use of intravitreal injection of anti- vascular endothelial growth factor(anti VEGF) therapy.Methods In this retrospective study a total of 986 intravitreal bevacizumab injections were applied between January 2008 andApril 2015 at the University Clinical Center Tuzla, Bosnia and Herzegovi...

By Svjetlana Terzić, Adisa Pilavdžić, Amra Nadarević Vodenčarević

Aim To investigate effects of post-sampling analysis time, a type of blood samples and collection tubes on blood gas testing.MethodsThis study included 100 patients at the Clinic for Pulmonary Diseases, Clinical Centre Sarajevo. The partial pressure ofoxygen (pO2) and carbon dioxide (pCO2), and the oxygen saturation level of hemoglobin (sO2) were a...

By Jasmina Smajić, Damira Kadić, Sabaheta Hasić, Nafija Serdarević

Aim To determine the impact of infarct localization and types of reperfusion therapy on the frequency of ventricular premature beats (VPBs) in patients with acute myocardial infarction (AMI) and reduced left ventricular ejection fraction (LVEF). Methods A total of 705 patients with acute ST elevation myocardial infarction (STEMI) were divided accor...

By Davor Horvat, Josip Vincelj

AimRecently increased attention and interest for Acinetobacterbaumanniiare the result of the occurrence of multidrug resistant(MDR), extensive drug resistant (XDR) and pandrug resistant (PDR) isolates around the world. The aim of this study was to examine the resistance of A. baumannii isolates to antimicrobials in Clinical Centre University of Sar...

By Amela Dedeić-Ljubović, Đana Granov, Mirsada Hukić

Aim To assess serum levels and correlation between uric acid (UA) and C-reactive protein (CRP) in acute coronary syndrome(ACS) and apparently healthy individuals.Methods The cross-sectional study included 116 examinees of age 44 to 83 years, distributed in two groups: 80 ACS patientsincluding 40 with acute myocardial infarction (AMI), and 40 with u...

By Emina Spahić, Sabaheta Hasić, Emina Kiseljaković, Halima Resić, Mehmed Kulić

Aim To compare efficacy and toxicity of bolus application of chemotherapy protocol, oxaliplatin, fluorouracil (bolus), leucovorin(folfox) between two groups of patients in the therapy of metastatic colorectal carcinoma (mCRC).Methods A total of 63 patients were treated for mCRC in the period January 2009 – January 2010 at the Department of On...

By Ibrahim Šišić, Belma Pojskić, Alma Mekić-Abazović, Vladimir Kovčin