Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings
Aim To investigate the characteristics of meticillin-resistant S. aureus (MRSA), extended-spectrum (ESBL), and plasmid-mediated AmpC beta-lactamase producing Gram-negative bacteria causing skin and soft tissue infections (SSTIs) in hospital and outpatient settings of Zenica-Doboj Canton, Bosnia and Herzegovina.Methods Antibiotic susceptibility was ...
By Selma Uzunović, Branka Bedenić, Ana Budimir, Amir Ibrahimagić, Farah Kamberović, Zlatko Fiolić, Michelle I. A. Rijnders, Ellen E. Stobberingh
Familial autoimmune thyroid disease and PTPN-22
Aim Autoimmune thyroid disease (AITD) is a multifactorial disease with a genetic predisposition. The protein tyrosine phosphatase-22 (PTPN-22) gene is a powerful inhibitor of T-cell activation. The aim of this study was to compare messenger RNA (mRNA) PTPN22 expression between healthy persons and patients with hypothyroidism and with their affected...
By Gabriel Conzuelo Rodríguez, Hugo Mendieta Zerón
Differences in body mass index and height factors between men with and without varicocele
Aim Despite many studies published in recent years concerning the relationship between demographic factors and varicocele, this issue remains controversial. The aim of this study was to identify a possible influence of body mass index (BMI) and height on occurrence varicocele in men.Methods In a case-control study 153 patients aged 18-40 years from...
By Hamid Shafi, Mouloud Agajani Delavar
Brucellosis in children in Bosnia and Herzegovina in the period 2000 - 2013
Aim To analyse clinical, laboratory and epidemiological characteristics of brucellosis in children in Bosnia and Herzegovina.Methods The study included 246 children aged 0-18 years, who were hospitalized in Clinics and Departments for Infectious Diseases in Tuzla, Sarajevo, Banja Luka, Zenica and Bihać in the period 2000-2013, in whom the diagnosis...
By Sead Ahmetagić, Humera Porobić-Jahić, Nada Koluder, Lejla Čalkić, Snježana Mehanić, Eldira Hadžić, Nevzeta Ibrahimpašić, Svjetlana Grgić, Mirela Zirić, Jelena Bajić, Denis Žepić
Possibilities of differentiation of solitary focal liver lesions by computed tomography perfusion
Aim To evaluate possibilities of computed tomography (CT) perfusion in differentiation of solitary focal liver lesions based ontheir characteristic vascularization through perfusion parameters analysis.Methods Prospective study was conducted on 50 patients in the period 2009-2012. Patients were divided in two groups: benignand malignant lesions. Th...
By Irmina Sefić Pašić, Anes Pašić, Spomenka Kristić, Adnan Beganović, Aladin Čarovac, Amra Dzananovic, Lidija Lincender, Sandra Vegar Zubović
Incidence of endophthalmitis after intravitreal application of anti VEGF therapy at the University Clinical Center in Tuzla, Bosnia and Herzegovina
Aim To report the incidence of endophthalmitis following the use of intravitreal injection of anti- vascular endothelial growth factor(anti VEGF) therapy.Methods In this retrospective study a total of 986 intravitreal bevacizumab injections were applied between January 2008 andApril 2015 at the University Clinical Center Tuzla, Bosnia and Herzegovi...
By Svjetlana Terzić, Adisa Pilavdžić, Amra Nadarević Vodenčarević
Therapeutic efficacy and toxicity of bolus application of chemotherapy protocol in the treatment of metastatic colorectal cancer
Aim To compare efficacy and toxicity of bolus application of chemotherapy protocol, oxaliplatin, fluorouracil (bolus), leucovorin(folfox) between two groups of patients in the therapy of metastatic colorectal carcinoma (mCRC).Methods A total of 63 patients were treated for mCRC in the period January 2009 – January 2010 at the Department of On...
By Ibrahim Šišić, Belma Pojskić, Alma Mekić-Abazović, Vladimir Kovčin
Impact of reperfusion therapy and infarct localization on frequency of premature ventricular beats in acute myocardial infarction
Aim To determine the impact of infarct localization and types of reperfusion therapy on the frequency of ventricular premature beats (VPBs) in patients with acute myocardial infarction (AMI) and reduced left ventricular ejection fraction (LVEF). Methods A total of 705 patients with acute ST elevation myocardial infarction (STEMI) were divided accor...
By Davor Horvat, Josip Vincelj
Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina
AimRecently increased attention and interest for Acinetobacterbaumanniiare the result of the occurrence of multidrug resistant(MDR), extensive drug resistant (XDR) and pandrug resistant (PDR) isolates around the world. The aim of this study was to examine the resistance of A. baumannii isolates to antimicrobials in Clinical Centre University of Sar...
By Amela Dedeić-Ljubović, Đana Granov, Mirsada Hukić
Positive correlation between uric acid and C-reactive protein serum level in healthy individuals and patients with acute coronary syndrome
Aim To assess serum levels and correlation between uric acid (UA) and C-reactive protein (CRP) in acute coronary syndrome(ACS) and apparently healthy individuals.Methods The cross-sectional study included 116 examinees of age 44 to 83 years, distributed in two groups: 80 ACS patientsincluding 40 with acute myocardial infarction (AMI), and 40 with u...
By Emina Spahić, Sabaheta Hasić, Emina Kiseljaković, Halima Resić, Mehmed Kulić