Aim To explore the effects of a molecular pathway from the application of low-intensity direct current (LIDC) for wound healingthrough the pathway signalling growth factor and initiation of fibroblast activation.Methods This randomized clinical trial included 32 patients with open fracture wounds who came to Hasan Sadikin Hospital inBandung, Indone...

By Yoyos Dias Ismiarto, Kemas Abdul Mutholib Luthfi, Mahyudin Mahyudin, Adriel Benedict

Aim In the scientific literature there are no papers that clarify which method of surgical fixation in transverse metacarpal fractures has the best functional outcomes. The aim of this study was to compare the hand strength obtained using two different methods in the treatment of these fractures.Methods A total of 52 patients who presented a transv...

By Andrea Pasquino, Alessandro Tomarchio, Enio De Cruto, Jacopo Conteduca, Damiano Longo, Valentina Russi, Giuseppe Pica, Luigi Meccariello, Giuseppe Rollo

Aim Children with congenital heart diseases are at the greater risk of respiratory tract infection such as pneumonia. Recurrent pneumonia is one of the most major challenge for paediatric physicians. The aim of this study is to investigate risk factors of congenital heart diseases to recurrent pneumonia children.Methods This was a retrospective stu...

By Sri Endah Rahayuningsih, Rahmat Budi Kuswiyanto, Filla Reviyani Suryaningrat, Heda Melinda Nataprawira, Abdurachman Sukadi

Aim To assess the impact of semi-refined carrageenan (E407a) on hydrophobic regions of phosphololipid bilayer in cell membranes of leukocytes collected from rats orally administered this food additive and white blood cells incubated with E407a.Methods Fluorescent probes (ortho-hydroxy derivatives of 2,5-diaryl-1,3-oxazole) were used to estimate the...

By Anton Tkachenko, Anatolii Onishchenko, Alexander Roshal, Oksana Nakonechna, Tetyana Chumachenko, Yevgen Posokhov

Balneo-gynaecological treatment methods include external bath hydrotherapy, sedentary baths and topical dressings/cataplasm, and internal (intravaginal or intrarectal use of peloids and mineral water). Hyperosmolar thermal spas have been very popular in the treatment of infertility due to the improvement of symptoms of chronic pelvic pain, endometr...

By Dubravko Habek, Anis Cerovac, Lejla Kamerić, Enida Nevačinović, Adnan Šerak

Rotator cuff tears (RCT) are a common problem encountered by orthopaedic surgeons. The incidence of re-tears (up to 94%) following surgical repair of RCTs renders the management of RCTs challenging. This higher re-tear rate has been attributed to the failure of healing at the tendon-bone junction. Biological augmentation methods such as growth fact...

By Erdi Özdemir, Dogac Karaguven, Egemen Turhan, Gazi Huri

Aim A SARS Coronavirus 2 (COVID-19) pandemic drastically changed the way the health system works. In Croatia, lockdownmeasures to curb virus spread lasted from March to May 2020, and all non-essential medical procedures and patients’ visits have been cancelled. The study aimed to compare patients’ flow and interventions in the surgical ...

By Ana Kvolik Pavić, Vedran Zubčić, Slavica Kvolik

Aim Thyroid nodules are very common and may be found in more than 50% of the population. Fine-needle aspiration cytology(FNAC) of thyroid nodules is a very useful diagnostic tool with high sensitivity and predictive value for diagnosis. The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) uses six categories for thyroid cytology reportin...

By Francesk Mulita, Fotios Iliopoulos, Christos Tsilivigkos, Levan Tchabashvili, Elias Liolis, Charalampos Kaplanis, Ioannis Perdikaris, Ioannis Maroulis

Aim Vascular pathologies have been already explored for the most of their aspects. It is a group of pathologies with unclear ethology and with an evolution in time not easy to forecast. Treatment guidelines are conflicting. The aim of this study was to describe cases in their most practical and technical aspect, especially in complicated conditions...

By Gianpaolo Santini, Pasquale Quassone, Luca Tarotto, Francesco Arienzo, Giuseppe Sarti

Aim To investigate the effect of umbilical cord-derived mesenchymal stem cells (UC-MSCs) administration among liverfibrosis experimental rat model via the regulation of angiotensin II type 1 receptor (AT1R) and platelet-derived growth factor-β (PDGF-β) due to their therapeutic potential to replace liver transplantation for advanced liver ...

By Taufik Sungkar, Agung Putra, Dharma Lindarto, Rosita Juwita Sembiring