Aim Chromosome translocations are considered as one of the most severe forms of genome defects. Because of the clinical significance of chromosome translocations and scarce data on the incidence of sporadic translocations in population of Bosnia and Herzegovina, we aimed to report sporadic translocation frequencies in samples karyotyped in our labo...

By Sanin Haverić, Anja Haverić, Maida Hadžić, Tamara Ćetković, Lejla Čaluk Klačar, Rifat Hadžiselimović

Aim Bone defect is a challenge even for experienced orthopaedic surgeons and it is a significant cause of morbidity in patients and a source of high economic burden in health care. A severe bone defect is a condition whereby the bone tissue cannot undergo natural healing despite surgical stabilization and requires further surgical intervention. Str...

By Panji Sananta, Respati S Dradjat, Rizqi Daniar Rosandi, Lasa Dhakka Siahaan

Aim To investigate changes in bone and cartilage tissue during the use of non-steroidal anti-inflammatory drugs and paracetamol in experimental osteoarthritis and hypothyroidism by the markers CTX-I and CTX-II.Methods The experiments were performed on 75 white nonlinear rats of both sexes, which recreated osteoarthritis and hypothyroidism. Experime...

By Dmytriy Sergeevich Nosivets

Aim To assess a psychosocial impact of the Coronavirus disease 2019 (COVID-19) on health care workers and to quantify the size of depression symptoms, anxiety and stress levels.Methods This cross-sectional study used an anonymous online survey questionnaire as a research instrument and it included 114health workers of all profiles from the Sarajevo...

By Aleksandra Pašić, Slavenka Štraus, Emina Smajić, Ermin Begović, Ilirijana Haxhibeqiri-Karabdić, Nada Spasojević

Aim To investigate the role of short-term diazepam therapy for improving long-term outcomes and reducing neck pain after whiplash injury.Methods A total of 89 patients suffering from whiplash injury were included. They were randomly assigned into 2 groups: groupA (study group), and group B (control group). The test group was prescribed with diazepa...

By Edin Mešanović, Ćamil Habul, Ermin Hadžić

Aim COVID-19 pandemic caused by SARS-CoV-2 is spreading throughout the world affecting both healthy individuals and people with underlying immune-deficiencies. People living with human immunodeficiency virus (HIV) consist a group multiply affected by this universal crisis.Methods Literature search aiming to identify relevant publications referring ...

By Dimitrios Bousis, Francesk Mulita, Ioanna Marlafeka, Themistoklis Paraskevas, Dimitrios Velissaris

Aim Several biomarkers are currently used as diagnostic and prognostic tools in patients with cancer. Soluble urokinase plasminogen activator receptor (suPAR) is elevated in acute and chronic inflammatory procedures and several observational studies during the last 20 years have investigated its role in oncology. The purpose of this article was to ...

By Themistoklis Paraskevas, Francesk Mulita, Christos Michailides, Georgios-Ioannis Verras, Elias Liolis, Eleousa Oikonomou, Ioannis Perdikaris, Panagiotis Perdikaris, Konstantinos Bouchagier, Ioannis Panagiotopoulos, Dimitrios-Ioannis Kasartzian, Dimitrios Filis, Levan Tchabashvili, Despoina Spyropoulou, Dimitrios Velissaris

Aim The COVID-19 pandemic has had a major impact on societies and has required adjustments of health systems and changes in work processes, especially in the light of an aging population with increased morbidity and mortality. The primary health care level has a key role in maintaining access to healthcare and in addressing the largest proportion o...

By Jurica Ferenčina, Vladimira Tomšič

Aim Knee osteoarthritis is a common osteoarthritis, which limits individual’s activity and affects aspects of daily life and quality of life. The prevalence of osteoarthritis in Indonesians is still high, reaching 12.7% in women and 15.8% in men. Based on the WHO, the prevalence of osteoarthritis in the world is still high, with 18% in women ...

By Panji Sananta, Avicenna Rahmanda, Dhelya Widasmara, Eka Noviya Fuzianingsih

Aim Knee osteoarthritis is a common osteoarthritis, which limits individual’s activity and affects aspects of daily life and quality of life. The prevalence of osteoarthritis in Indonesians is still high, reaching 12.7% in women and 15.8% in men. Based on the WHO, the prevalence of osteoarthritis in the world is still high, with 18% in women ...

By Panji Sananta, Avicenna Rahmanda, Dhelya Widasmara, Eka Noviya Fuzianingsih