Mid-term outcomes in the treatment of retroperitoneal sarcomas: a 12-year single-institution experience
Aim To present the experience from collective data regarding patients with retroperitoneal sarcomas that have been operated in and followed up by the University General Hospital of Patras in Rion, Greece, between 2009 and 2020.Methods A retrospective analysis of adult patients treated at our hospital with a diagnosis of primary retroperitoneal sarc...
By Georgios-Ioannis Verras, Francesk Mulita, Konstantinos Bouchagier, Dimitrios Bousis, Dimitrios Kehagias, Elias Liolis, Ioannis Perdikaris, Dimitrios Filis, Panagiotis Perdikaris, Ioannis Panagiotopoulos, Ioannis Maroulis, Nikolaos Benetatos
The effect of statin administration on IL-6 and IL-1b expression in peripheral blood mononuclear cells of a hypertensive patient with SARS-CoV-2 spike protein stimulation
Aim The infection of the SARS-CoV-2 virus potentially causes a cytokine storm with elevated IL-6 and IL-1β levels. Statin therapy was common among COVID-19 patients due to their cardiovascular comorbidities. However, the effect of statins on COVID-19 infection is unclear. The aim of this study was to evaluate the impact of statin administratio...
By Andrianto Andrianto, Budi Susetyo Pikir, Rizki Amalia, Teuku Yusriza, Fatimah Alzahra, Maya Qurota A’yun, Michael Jonatan
The efficacy and safety of electrolyzed water against Covid-19 as an alternative hand sanitizer
Aim To investigate the efficacy of electrolyzed water against viruses and its safety to the skin.Methods Virus culture was carried out at level-3 Bio-Safety (BSL3) facilities. The test material was prepared at room temperaturemixed with one part virus suspension and one organic load. As an antiseptic and disinfectant control, 0.7% formaldehyde was ...
By Rachmat Hidayat, Patricia Wulandari
Ultrasound guided fine needle aspiration cytology (FNAC): an assessment of the diagnostic potential in histologically proven thyroid nodules
Aim Results of ultrasound guided fine needle aspiration cytology (FNAC) as the compatibility of cytological findings with histopathological diagnoses (the "gold standard") in the diagnosis of nodular thyroid lesions are inconsistent. The aim of this prospective study was to determine the validity of FNAC, as well as the compatibility of findings wi...
By Branko Krišto, Ivana Vidović Krželj, Ana Krželj, Roberta Perković
Association between donor’s age and expression of cardiomyocyte marker quantity on adipocyte-derived mesenchymal stem cell
Aim Adipocyte-derived mesenchymal stem cells (AMSCs) have recently been studied as a potential new approach for regeneration treatment of heart failure and ischemic myocardium. However, donor’s age is thought to affect the ability of AMSC cells to differentiate into cardiomyocytes. This study aimed to analyse the association between donor&rsq...
By Bagus Fitriadi, Budi Baktijasa Dharmadjati, Mohammad Budiarto, Ryan Enast Intan, Firas Farisi Alkaff
Regulation of p53 and survivin by Curcuma longa extract to caspase-3 dependent apoptosis in triple negative breast cancer cells
Aim Triple negative breast cancer cells (TNBC) are the population of breast cancer cells that are responsible for cancer recurrence and apoptosis resistance. Unfortunately, current therapies have limited efficacy to TNBC population due to apoptosis resistance and chemoresistance. Tumour suppressor p53 and survivin are primary targets for TNBC thera...
By Deryne Anggia Paramita, Dedy Hermansyah, Desiree Anggia Paramita, Nur Dina Amalina
A comparison of different doses of fentanyl for patients undergoing elective colonoscopy: a randomized double-blind clinical trial
Aim To investigate analgesic and side effects of different doses of fentanyl in combination with propofol for colonoscopy.Methods This prospective randomized double-blind study conducted between 2019 and 2020 included 64 patients. Patients were randomized: Group 1 (fentanyl 0.5 μg/kg) and Group 2 (fentanyl 1.0 μg/kg) both in combination with ...
By Mirza Kovačević, Adisa Šabanović Adilović, Nermina Rizvanović, Harun Adilović, Malik Ejubović, Alma Jahić Čampara
Prognostic value of colour Doppler brain sonography for the neurodevelopmental outcome in term neonates with hypoxic ischaemic encephalopathy
Aim To determine a prognostic value of cerebral blood flow parameters for the development of neurological sequelae in term neonates with hypoxic ischaemic encephalopathy (HIE).Methods We reviewed medical records of 47 term neonates with HIE who survived until the age of 12 months of life. According tothe Sarnat and Sarnat clinical score, neonates w...
By Emina Hadžimuratović, Suada Branković, Admir Hadžimuratović, Melika Bukvić
Adherence to preventive behaviours and risk of COVID-19 infection: a case-control study
Aim To investigate the relationship between adherence to preventive behaviors and risk of COVID-19 infection.Methods In this case-control study, 491 participants were selected through convenience sampling. First, the samples of the casegroup (COVID-19 patients) were selected, and then the control group was matched with the case group based on age, ...
By Reza Hosseinabadi, Shoorangiz Biranvand, Khatereh Anbari
Vascular comorbidities in patients with multiple sclerosis and their impact on physical disability
Aim Given the impact of vascular comorbidities (VC) on the diagnosis, treatment, and outcome of multiple sclerosis (MS), weexamined the incidence and correlation of VC and risk factors for vascular disease in people with MS (PwMS) compared to the general population, and the impact on the physical disability of patients.Methods Cross-sectional study...
By Daliborka Tadić, Sanja Grgić, Aleksandra Dominović-Kovačević, Majda Nazalević-Bursać, Srđan Mavija, Vlado Đajić