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Original article

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Impact of lung ultrasound-guided therapeutic approach on haemodialysis treatment in patients with ischemic heart failure

By
Nejra Prohic Orcid logo ,
Nejra Prohic
Contact Nejra Prohic

Department of Internal Medicine, General Hospital "Prim. Dr Abdulah Nakaš" , Sarajevo , Bosnia and Herzegovina

Belma Paralija ,
Belma Paralija

Deparment for Lung Diseases, Clinic for Lung Diseases, Clinical Centre, University of Sarajevo , Sarajevo , Bosnia and Herzegovina

Halima Resic ,
Halima Resic

Department for Scientific Work, General Hospital "Prim. Dr Abdulah Nakaš" Bosnia and Herzegovina

Edin Begic
Edin Begic

Department for Cardiology, General Hospital "Prim. Dr Abdulah Nakaš" , Sarajevo , Bosnia and Herzegovina

Abstract

Aim Lung ultrasound (LUS) can be used for an assessment of volume overload in patients with end-stage kidney disease (ESKD) and those undergoing dialysis. The aim of this study was to analyse whether the initial use of LUS in evaluating volume status could benefit patients by optimizing haemodialysis treatment and improving their clinical status.
Methods The study included 50 haemodialysis patients in stage V of ESKD with the diagnosis of ischaemic heart failure with reduced (HFrEF) or midrange ejection fraction (HFmrEF). The assessment of volume status was verified solely by LUS (along with the analysis of B lines as measures of volume status). The specified laboratory parameters were performed initially, after three, and after six months.
Results The number of B-lines on LUS were decreased during the six-month follow-up compared to baseline, indicating a reduction in volume overload due to the LUS-guided protocol. Statistically significant differences were observed in the average creatinine (p=0.001) and parathormone (PTH) (p=0.003) levels over the six-month monitoring period. Significant differences were also noted in triglyceride (p=0.000) and potassium (p=0.02) levels. No significant differences were found in the values of other monitored parameters. 
Conclusion In haemodialysis patients diagnosed with heart failure, LUS can aid the achievement of a more efficient volume reduction by decreasing B-lines, which are indicative of congestion. Our study also demonstrated beneficial effects of LUS on potassium and parathormone levels.

Author Contributions

Conceptualization, N.P., B.P., H.R. and E.B.; Data curation, N.P. and E.B.; Formal Analysis, N.P., H.R. and E.B.; Funding acquisition, N.P., B.P. and E.B.; Investigation, N.P., B.P. and H.R.; Methodology, N.P., B.P. and E.B.; Project administration, N.P., B.P., H.R. and E.B.; Resources, N.P., B.P., H.R. and E.B.; Software, N.P., B.P., H.R. and E.B.; Supervision, N.P., B.P., H.R. and E.B.; Validation, N.P., B.P., H.R. and E.B.; Visualization, N.P., B.P., H.R. and E.B.; Writing – original draft, N.P., B.P., H.R. and E.B.; Writing – review & editing, N.P., B.P., H.R. and E.B. All authors have read and agreed to the published version of the manuscript.

Citation

Data Availability

Data is available on request

Funding Statement

None

Authors retain copyright. This work is licensed under a Creative Commons Attribution 4.0 International License. Creative Commons License

 

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