Aim Vulvovaginal candidiasis (VVC) is a disease mostly caused by Candida albicans and affects the quality of life of women especially in the form of chronic recurrent vulvovaginal candidiasis (RVVC). Nigella sativa is known to have several effects such as antimicrobial, anti-inflammatory, immune stimulation and anticancer properties. The aim of thi...

By Muhammad Rusda, Muhammad Fidel Ganis Siregar, Aznan Lelo, Syafruddin Ilyas, Ratna Akbari Ganie, Yusuf Effendi, Poppy Anjelisa Zaitun Hasibuan, Raden Roro Lia Iswara

Aim To assess ten-year risk of diabetes mellitus type 2 (T2DM) using the Finnish Diabetes Risk Score (FINDRISC) in respondents over 18, in Primary Health Centre in Banja Luka. Methods A prospective study was conducted using data from a population with undiagnosed T2DM in Primary Health Centre in Banja Luka. Eligible respondents were those aged 18 t...

By Suzana Savić, Saša Stanivuković, Biljana Lakić

Aim To assess the effect of snakehead fish extract administration in angiogenesis focusing on the level of vascular endothelial growth factor (VEGF), nitric oxide (NO) and VEGF receptor 2 (R2) expression is ischemic stroke models. Methods An experimental study was conducted on 5 groups of ischemic stroke rats models: Group K-without carotid artery ...

By Iskandar Nasution, Hasan Sjahrir, Syafruddin Ilyas, Muhammad Ichwan

In contrast to classical appendectomy where the appendiceal stump is secured by a single or double ligature, in laparoscopic appendectomy various ways of securing the stump are mentioned. Each of these methods has advantages and disadvantages. Since different possibilities exist for closing the stump, it is very important to find the optimum method...

By Samir Delibegović, Reuf Karabeg, Milan Simatović

Aim Multifragmentary segmental femoral shaft fracture is a high energy injury frequently associated with life-threatening conditions. The aim of this study was to compare the use of bio metallic open reduction internal fixation (ORIF) (plate with allograft bone strut) with minimally invasive plate osteosynthesis (MIPO) fixation for the treatment of...

By Giuseppe Rollo, Mario Ronga, Enrico Maria Bonura, Rocco Erasmo, Michele Bisaccia, Paolo Pichierri, Antonio Marsilio, Andrea Pasquino, David Gomez Garrido, Raffaele Franzese, Andrea Schiavone, Luigi Meccariello

Aim The gradual increase in shoulder implants in active elderly patients has appeared in a parallel increase in periprosthetic humeral fractures. The aim of this study was to investigate the advantages of using strut grafting with plate fixation during periprosthetic humerus fractures.Methods Thirty patients diagnosed with periprosthetic humeral fr...

By Giuseppe Rollo, Michele Biserni, Gazi Huri, Christian Carulli, Mario Ronga, Michele Bisaccia, David Gomez-Garrido, Nezih Ziroglu, Enrico Maria Bonura, Andrea Alberto Ruberti, Andrea Schiavone, Luigi Meccariello

Aim To analyse the ability of mesenchymal stem cells (MSCs) to regulate interleukin 6 (IL-6) and transforming growth factor (TGF-β) expression in vitro under co-culture conditions in human systemic lupus erythematosus (SLE). MethodThis study used a post-test group design that used peripheral blood mononuclear cells (PBMCs) from SLE patients at...

By Dewi Masyithah Darlan, Delfitri Munir, Nelva Karmila Jusuf, Agung Putra, Riyadh Ikhsan, Iffan Alif

Aim Chronic Suppurative Otitis Media (CSOM) with or without cholesteatoma is a global major problem and it is becoming a burden especially in developing countries. Studies have found that ethanol extracts of Puguntano leaves obtained by the percolation and socletation methods have phytochemical contents that provide anti-inflammatory effect. The ai...

By Harry A. Asroel, Aznan Lelo, Delfitri Munir, Jenny Bashiruddin, Restu Syamsul Hadi

Aim ABO blood group genotypes are established as a genetic factor in pathophysiology of various diseases, such as cardiovascular disorders, cancers, infectious diseases and there is rising evidence of their involvement in other conditions. The aim of this study was to determine if ventilatory changes of lung function in asthma, measured by biomarke...

By Marina Lampalo, Irena Jukić, Jasna Bingulac-Popović, Hana Safić Stanić, Nikola Ferara, Sanja Popović-Grle

Aim To present characteristics of collecting autologous peripheral blood stem cells over a one-year period with an emphasis on efficiency and safety. Methods A retrograde analysis of 24 leukapheresis in 20 adult patients with malignant haematological diseases in the Blood Transfusion Institute of the Federation of Bosnia and Herzegovina in Sarajevo...

By Gorana Ahmetović-Karić, Elma Ćatović-Baralija, Alma Sofo-Hafizović