Aim Allergic rhinitis (AR) is a heterogeneous condition that has been associated with inflammatory responses and is characterized by clinical typical symptoms of nasal itching, sneezing, watery discharge and congestion. Mesenchymal stem cells (MSCs) are multipotent stem cells that have the immunoregulatory ability by secreting various cytokines whi...

By Lia Restimulia, Syafruddin Ilyas, Delfitri Munir, Agung Putra, Teti Madiadipoera, Farhat Farhat, Rosita Juwita Sembiring, Muhammad Ichwan, Nur Dina Amalina

Aim To investigate analgesic and side effects of different doses of fentanyl in combination with propofol for colonoscopy.Methods This prospective randomized double-blind study conducted between 2019 and 2020 included 64 patients. Patients were randomized: Group 1 (fentanyl 0.5 μg/kg) and Group 2 (fentanyl 1.0 μg/kg) both in combination with ...

By Mirza Kovačević, Adisa Šabanović Adilović, Nermina Rizvanović, Harun Adilović, Malik Ejubović, Alma Jahić Čampara

Aim To investigate the effect of umbilical cord-derived mesenchymal stem cells (UC-MSCs) administration among liverfibrosis experimental rat model via the regulation of angiotensin II type 1 receptor (AT1R) and platelet-derived growth factor-β (PDGF-β) due to their therapeutic potential to replace liver transplantation for advanced liver ...

By Taufik Sungkar, Agung Putra, Dharma Lindarto, Rosita Juwita Sembiring

Aim A SARS Coronavirus 2 (COVID-19) pandemic drastically changed the way the health system works. In Croatia, lockdownmeasures to curb virus spread lasted from March to May 2020, and all non-essential medical procedures and patients’ visits have been cancelled. The study aimed to compare patients’ flow and interventions in the surgical ...

By Ana Kvolik Pavić, Vedran Zubčić, Slavica Kvolik

Aim To establish a correlation between immediate post-surgical weight bearing in extracapsular hip fractures and final functional outcome as well as to study the correlation between immediate post-surgical weight bearing and morbidity and mortality during the first year.Methods Retrospective observational cohort study including 495 consecutive pati...

By Enrique Sanchez-Munoz, Beatriz Lozano-Hernanz, Daniel Vicente Velarde-Garrido, Leticia Alarma-Barcia, Victor Trivino Sanchez-Mayoral, Paula Romera-Olivera, Cristina Lopez Palacios

Aim To characterize methicillin-resistant S. aureus (MRSA) strains phenotypically and genotypically and to determine their clonal affiliation, representation and antibiotic resistance profile.Methods A total of 62 randomly selected MRSA isolates of different clinical samples collected from 2009 to 2017 were phenotypically and genotypically analysed...

By Fatima Numanović, Urška Dermota, Jasmina Smajlović, Sandra Janežič, Nijaz Tihić, Zineta Delibegović, Amela Bećirović, Edina Muratović, Merima Gegić

Aim Vascular pathologies have been already explored for the most of their aspects. It is a group of pathologies with unclear ethology and with an evolution in time not easy to forecast. Treatment guidelines are conflicting. The aim of this study was to describe cases in their most practical and technical aspect, especially in complicated conditions...

By Gianpaolo Santini, Pasquale Quassone, Luca Tarotto, Francesco Arienzo, Giuseppe Sarti

Aim The septic non-union is a common compliance in bone healing due to bone infection. Bone resection, associated with Ilizarov osteo-distraction technique, is commonly used in these cases. The aim of this study was to analyse clinical and radiological results of teriparatide in combination with the Ilizarov technique and to compare this treatment ...

By Giuseppe Rollo, Francesco Luceri, Gabriele Falzarano, Carlo Salomone, Enrico Maria Bonura, Dmitry Popkov, Mario Ronga, Giuseppe Pica, Michele Bisaccia, Valentina Russi, Predrag Grubor, Raffaele Franzese, Giuseppe M. Peretti, Luigi Meccariello

Aim To present haemoglobin and ferritin parameters in donors to highlight the importance of serum ferritin testing for the purpose of evaluating iron depots in order to make recommendations for preserving a population of blood donors.Method A prospective study was conducted on 80 blood donors divided in two groups: group I (regular donors, n =40) a...

By Elma Ćatović-Baralija, Gorana Ahmetović-Karić, Sabaheta Hasić, Nesina Avdagić, Nermina Babić

Aim To investigate the effects of surgical reduction of complex acetabular fractures on spine balance, postural stability and quality of life.Methods Twenty-six patients with acetabular fractures surgically treated by open reduction and internal fixation were divided intotwo groups according to the amount of reduction. Group A consisted of 18 patie...

By Vitaliano F. Muzii, Giuseppe Rollo, Guido Rocca, Rocco Erasmo, Gabriele Falzarano, Francesco Liuzza, Michele Bisaccia, Giuseppe Pica, Raffaele Franzese, Luigi Meccariello