Aim To assess trends in thrombolysis rates and door-to-needle times in University Hospital Mostar.Methods Data from the University Hospital Mostar Registry were used. Information on the number of ischaemic stroke patients, intravenous thrombolysis rates and „door-to-needle times“ (DNT) were collected between January 2013 and December 20...

By Marija Bender, Stjepan Čović, Matea Baranik, Sandra Lakičević, Inge Klupka-Sarić

Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenileidiopathic arthritis (JIA) at the disease onset.Methods A retrospective review of medical records of 25 HLAB27 positive and 25 HLA-B27 negative JIA patients was performed. The diagnosis of JIA was based on the 1997-2001 Int...

By Adisa Čengić, Velma Selmanović, Sniježana Hasanbegović, Nedim Begić, Emina Karčić, Elma Fejzić

Aim Triple negative breast cancer cells (TNBC) are the population of breast cancer cells that are responsible for cancer recurrence and apoptosis resistance. Unfortunately, current therapies have limited efficacy to TNBC population due to apoptosis resistance and chemoresistance. Tumour suppressor p53 and survivin are primary targets for TNBC thera...

By Deryne Anggia Paramita, Dedy Hermansyah, Desiree Anggia Paramita, Nur Dina Amalina

Aim To investigate the relationship between adherence to preventive behaviors and risk of COVID-19 infection.Methods In this case-control study, 491 participants were selected through convenience sampling. First, the samples of the casegroup (COVID-19 patients) were selected, and then the control group was matched with the case group based on age, ...

By Reza Hosseinabadi, Shoorangiz Biranvand, Khatereh Anbari

Aim Given the impact of vascular comorbidities (VC) on the diagnosis, treatment, and outcome of multiple sclerosis (MS), weexamined the incidence and correlation of VC and risk factors for vascular disease in people with MS (PwMS) compared to the general population, and the impact on the physical disability of patients.Methods Cross-sectional study...

By Daliborka Tadić, Sanja Grgić, Aleksandra Dominović-Kovačević, Majda Nazalević-Bursać, Srđan Mavija, Vlado Đajić

Aim The infection of the SARS-CoV-2 virus potentially causes a cytokine storm with elevated IL-6 and IL-1β levels. Statin therapy was common among COVID-19 patients due to their cardiovascular comorbidities. However, the effect of statins on COVID-19 infection is unclear. The aim of this study was to evaluate the impact of statin administratio...

By Andrianto Andrianto, Budi Susetyo Pikir, Rizki Amalia, Teuku Yusriza, Fatimah Alzahra, Maya Qurota A’yun, Michael Jonatan

Aim Knee osteoarthritis is a common osteoarthritis, which limits individual’s activity and affects aspects of daily life and quality of life. The prevalence of osteoarthritis in Indonesians is still high, reaching 12.7% in women and 15.8% in men. Based on the WHO, the prevalence of osteoarthritis in the world is still high, with 18% in women ...

By Panji Sananta, Avicenna Rahmanda, Dhelya Widasmara, Eka Noviya Fuzianingsih

Aim Several biomarkers are currently used as diagnostic and prognostic tools in patients with cancer. Soluble urokinase plasminogen activator receptor (suPAR) is elevated in acute and chronic inflammatory procedures and several observational studies during the last 20 years have investigated its role in oncology. The purpose of this article was to ...

By Themistoklis Paraskevas, Francesk Mulita, Christos Michailides, Georgios-Ioannis Verras, Elias Liolis, Eleousa Oikonomou, Ioannis Perdikaris, Panagiotis Perdikaris, Konstantinos Bouchagier, Ioannis Panagiotopoulos, Dimitrios-Ioannis Kasartzian, Dimitrios Filis, Levan Tchabashvili, Despoina Spyropoulou, Dimitrios Velissaris

Aim To investigate possible differences in serum glucose and sodium and potassium concentrations with respect to age, gender and severity of diabetic ketoacidosis.Methods Medical records from 1 January 2017 to 31 December 2019 were reviewed and patients with the diagnosis of diabeticketoacidosis were selected.Results The study included 52 patients....

By Željka Dragila, Dora Rudić, Klara Ćosić, Tatjana Bačun

Aim To determine a prognostic value of cerebral blood flow parameters for the development of neurological sequelae in term neonates with hypoxic ischaemic encephalopathy (HIE).Methods We reviewed medical records of 47 term neonates with HIE who survived until the age of 12 months of life. According tothe Sarnat and Sarnat clinical score, neonates w...

By Emina Hadžimuratović, Suada Branković, Admir Hadžimuratović, Melika Bukvić