Aim To determine the serum levels of matrix metalloproteinase 9 (MMP-9) concentration and their association with the stage and histopathologic sizes of colorectal cancer (CRC). Methods One hundred and two patients with clinically diagnosed and histologically confirmed colorectal cancer ready for surgical treatment were included in the study. In eac...

By Ismar Rašić, Azra Rašić, Goran Akšamija, Svjetlana Radović, Nedžad Šehović

Aim The aim of the study is to evaluate the effect of a prospectively conducted interactive 5-day education programme based on Düsseldorf model on glycated haemoglobin (A1C), and total daily dose of insulin in type 1 diabetes patients. Methods A total of 67 type 1 diabetes patients was analysed; mean age of 11±0.68 years, 43 females and...

By Diana Štimjanin-Koldžo, Salem Alajbegović, Ena Štimjanin, Jasmina Mehinagić

Aim To evaluate biomechanical and clinical outcomes of a newly developed modification of the Wilson's osteotomy for hallux valgus: a three-dimensional subcaptial correction of the metatarsal head position with a simultaneous lateral and plantar shift with derotation intended to reduce displacement of the distal fragment and shortening of the first ...

By Robert Kolundžić, Mladen Mađarević, Vladimir Trkulja, Tomislav Crnković, Igor Šmigovec, Daniel Matek

Aim Rosa damascene Mill. belongs to the family of Roseaceae and its essential oil is produced in large amounts in Iran. The wide application of rose oil has raised questions about potential adverse health effects. We have investigated cytotoxic activity and genotoxic effects of Rosa oil from Kashan, Iran. Methods The cytotoxic effect and IC50 of th...

By Mohammad Shokrzadeh, Emran Habibi, Mona Modanloo

Aim To evaluate the demographic and clinical data of fifty two patients with the diagnosis of ulcerative colitis. Methods A total of 52 patients diagnosed with ulcerative colitis by clinical, endoscopical and histopathological evaluations were included the study. Demographic data, colon involvement site of the disease and disease severity were exam...

By Hatice Karagoz, Abdulsamet Erden, Hatice Karaman, Ahmet Karaman

Aim To investigate the age (in months) at which motor skills are developed in children with Down syndrome (DS), and compare it to the age of the development of the same skills in both, children with typical development (TD), and children with DS reported by four other studies. Methods Sixteen children (7 girls and 9 boys) were monthly assessed for ...

By Samire Beqaj, Njomza Jusaj, Vujica Živković

Aim To analyse the long-term impact of altered metabolism on the level of mediators of inflammatory response in female patients with type 2 diabetes. Methods This study included 97 female patients with type 2 diabetes and 107 female, nondiabetic control subjects, who were recruited at the Clinical Centre University of Sarajevo and the General Hospi...

By Maja Malenica, Mira Šilar, Tanja Dujić, Tamer Bego, Sabina Semiz, Selma Škrbo, Besim Prnjavorac, Adlija Čaušević

Aim Concurrent chemoradiotherapy (CRT) is the standard of care for locally advanced, unresectable non-small cell lung carcinoma (NSCLC). The aim of this study was to assess the prognostic value of maximum standardized uptake values (SUV max) in patients with unresectable stage III NSCLC treated with concurrent CRT. Method 18 F-FDG PET-CT scans were...

By Ufuk Yılmaz, Yasar Zehra, Esra Korkmaz, Burcu Yalcın, Hakan Koparal, Engin Ozbilek

Aim To determine socioeconomic and demographic factors associated with abdominal obesity in women of childbearing age. Methods This cross-sectional study was carried out in family medicine outpatient departments of the Primary Health Care Centre of Canton Sarajevo, Bosnia and Herzegovina. The study included 300 respondents who were divided into two...

By Amira Kurspahić-Mujčić, Emir Zećo

Aim To investigate the effects of carbocisteine treatment in the reduction of frequency of productive cough episodes, preventing disease progression and improving the quality of life as well as the tolerability of the administered treatment and patient compliance during the study. Methods This observational, non-interventional, multicenter, cohort ...

By Esad Alibašić, Amira Skopljak, Aida Čengić, Gorana Krstović, Nataša Trifunović, Tarik Čatić, Belma Kapo, Meliha Mehić, Amila Hadžimuratović