Correlation between numerical and categorical immunohistochemical score of Ki-67 and HER2 with clinicopathological parameters of breast cancer
Aim To evaluate the relationship between numerical and categorical immunohistochemical score of Ki-67 and human epidermal growth factor of receptor 2 (HER2) with clinicopathological parameters of breast cancer (BC).Methods The study included 311 patients with invasive BC diagnosed at the Department of Pathology, School of Medicine inSarajevo, Bosni...
By Mirsad Dorić, Suada Kuskunović-Vlahovljak, Edina Lazović Salčin, Svjetlana Radović, Nina Čamdžić, Mirsad Babić, Haris Čampara
Rare and uncommon diseases of the hip: arthroscopic treatment
Aim Uncommon and rare hip diseases are sources of pain and functional limitation particularly in young patients. Some of these conditions may be nowadays treated by arthroscopy due to the expertise and technical tips that high-volume hip arthroscopies have achieved during the last decades ensuring a wider range of indications for such a procedure. ...
By Christian Carulli, Alberto Schiavo, Alberto Rigon, Wondi De Marchi, Matteo Innocenti, Luigi Meccariello, Massimo Innocenti
Efficacy and safety of three plant extracts based formulations of vagitories in the treatment of vaginitis: a randomized controlled trial
Aim There are more and more herbal preparations that are used for the purpose of treatment and improvement of the clinical manifestation of vaginitis not only by patients themselves, but also by healthcare professionals. Plant species, St. John’s wort, chamomile, calendula, yarrow, shepherd’s purse and tea tree oil are all well known fo...
By Kemal Durić, Selma Kovčić Hadžiabdić, Mahira Durić, Haris Nikšić, Alija Uzunović, Hurija Džudžević Čančar
Traumatic bilateral scaphoid fractures
Aim To illustrate the surgical treatment of bilateral post-traumatic scaphoid fracture.Methods We came across a young student, who sustained bilateral, undisplaced scaphoid waist fractures following a fall during afootball match. Despite careful clinical and radiographic evaluation by four views at the Accident and Emergency (A&E) Department, w...
By Dariush Ghargozloo, Alessandro Tomarchio, Mauro Ballerini, Gianpaolo Chitoni
Epidemiology of hospitalized patients with peripheral arterial disease in Bosnia and Herzegovina
Aim To investigate a profile of patients with peripheral artery disease (PAD) in Bosnia and Herzegovina.Methods This observational study included 1022 patients hospitalized at the Clinical Centre University of Sarajevo in a 5-year period, 2015 to 2019.Results Disease prevalence rises sharply after the age of 50. Most patients, 797 (78%) had proxima...
By Akif Mlačo, Nejra Mlačo, Mevludin Mekić, Alen Džubur
Neurocysticercosis with symptomatic epilepsy manifestation
Aim To present a unique case of a 22-year-old male patient with symptomatic epilepsy manifestation on a background of neurocysticercosis (NCC). Methods An Indian student in Kharkiv, who lived in rural parts in India, presented with sudden episodes of seizure followed by severe headaches. Laboratory analyses and neurological status (MRI) were perfor...
By Nataliya Nekrasova, Olena Tovazhnyanska, Daryna Sushetska, Olena Markovska, Anton Shapkin, Rhea Singh, Yevhenija Soloviova, Dmytro Butov
Efficacy of Zhu’s acupuncture techniques to improve muscle strength of motion limbs in stroke patients
AimTo investigate the efficacy of Zhu acupuncture in motoric ability improvement of stroke patients. This research is a preliminary study in an effort to test the efficacy of Zhu's acupuncture technique in motor improvement in stroke patients.Methods This quasi-experimental study, with the pretest and posttest approach without control group design ...
By Indri Seta Septadina, Erial Bahar
Mesenchymal stem cells under hypoxia condition inhibit peritoneal adhesion by suppressing the prolonged release of interleukin-6
Aim To investigate the role of hypoxia-preconditioned mesenchymal stem cells (H-MSCs) in preventing peritoneal adhesionby regulating IL-6 at days 6 and 12.Methods Twenty-four PAs rat model weighing 250 g to 300 g were randomly allocated into 4 groups: sham (Sh), control (C),H-MSCs treatment group at dose 1.5 x 106 (T1) and 3 x 106 (T2). To in...
By Adi Muradi Muhar, Agung Putra, Vito Mahendra Ekasaputra, Dewi Masyithah Darlan, Desiree Anggia Paramita, Iqbal Pahlevi Adeputra Nasution
Intra-operative local plus systemic tranexamic acid significantly decreases post-operative bleeding and the need for allogeneic blood transfusion in total knee arthroplasty
Aim To evaluate the efficacy of systemic plus local tranexamic acid (TXA) in reducing post-operative bleeding, haemoglobin loss and the need for allogeneic blood transfusion (ABT) in total knee arthroplasty (TKA).Methods All patients undergoing TKA between January 2017 and September 2019 were retrospectively evaluated. Exclusion criteria were cardi...
By Lidia De Falco, Elisa Troiano, Martina Cesari, Pietro Aiuto, Giacomo Peri, Nicolò Nuvoli, Mattia Fortina, Nicola Mondanelli, Stefano Giannotti
The challenge of the surgical treatment of paediatric distal radius/ forearm fracture: K wire vs plate fixation - outcomes assessment
Aim Distal radius/forearm fractures in adolescent patients remain challenging injuries to treat. Distal radius/forearm bony anatomy is not completely restored with intramedullary K wire fixation. The aim of this study was to compare radiographic and functional outcomes obtained using intramedullary K wire fixation and open reduction and internal fi...
By Salvatore Di Giacinto, Giuseppe Pica, Alessandro Stasi, Lorenzo Scialpi, Alessandro Tomarchio, Alberto Galeotti, Vlora Podvorica, Annamaria dell’Unto, Luigi Meccariello