Aim To investigate analgesic effect of three different regimens of combination of analgesics administered to patients undergoing laparoscopic cholecystectomy.Methods Patients undergoing laparoscopic cholecystectomy were randomly allocated to one of three groups on admission, depending of a prescribed post-operative analgesic regimen. Patients alloc...

By Francesk Mulita, Georgios Karpetas, Elias Liolis, Michail Vailas, Levan Tchabashvili, Ioannis Maroulis

Aim To assess the impact of semi-refined carrageenan (E407a) on hydrophobic regions of phosphololipid bilayer in cell membranes of leukocytes collected from rats orally administered this food additive and white blood cells incubated with E407a.Methods Fluorescent probes (ortho-hydroxy derivatives of 2,5-diaryl-1,3-oxazole) were used to estimate the...

By Anton Tkachenko, Anatolii Onishchenko, Alexander Roshal, Oksana Nakonechna, Tetyana Chumachenko, Yevgen Posokhov

Aim To explore the effects of a molecular pathway from the application of low-intensity direct current (LIDC) for wound healingthrough the pathway signalling growth factor and initiation of fibroblast activation.Methods This randomized clinical trial included 32 patients with open fracture wounds who came to Hasan Sadikin Hospital inBandung, Indone...

By Yoyos Dias Ismiarto, Kemas Abdul Mutholib Luthfi, Mahyudin Mahyudin, Adriel Benedict

Aim To investigate the effect of intermittent traction therapy (ITT) on pain in patients with chronic low back pain (CLBP).Methods A total of 81 patients with CLBP were included: experimental group received ITT (n=40) and control group receivedconservative physical treatment (n=41) 10 times for two weeks. A visual analogue scale (VAS) was used for ...

By Edina Tanović, Damir Čelik, Đemil Omerović, Vanda Zovko Omeragić, Amila Jaganjac, Hadžan Konjo, Emina Rovčanin, Hana Omerović

Balneo-gynaecological treatment methods include external bath hydrotherapy, sedentary baths and topical dressings/cataplasm, and internal (intravaginal or intrarectal use of peloids and mineral water). Hyperosmolar thermal spas have been very popular in the treatment of infertility due to the improvement of symptoms of chronic pelvic pain, endometr...

By Dubravko Habek, Anis Cerovac, Lejla Kamerić, Enida Nevačinović, Adnan Šerak

Rotator cuff tears (RCT) are a common problem encountered by orthopaedic surgeons. The incidence of re-tears (up to 94%) following surgical repair of RCTs renders the management of RCTs challenging. This higher re-tear rate has been attributed to the failure of healing at the tendon-bone junction. Biological augmentation methods such as growth fact...

By Erdi Özdemir, Dogac Karaguven, Egemen Turhan, Gazi Huri

Aim To report clinical, functional and radiographic results of oneincision distal biceps tendon repair with Toggle Loc (Zimmer-Biomet, Warsaw, Indiana, USA) at an average 4-year follow-up and to assess posterior interosseous nerve injury complications after reconstruction.Methods We conducted a retrospective review of 58 consecutive distal biceps t...

By Silvio Chiossi, Marco Spoliti, Pasquale Sessa, Valerio Arceri, Attilio Basile, Francesca Romana Rossetti, Riccardo Maria Lanzetti

Aim Thyroid nodules are very common and may be found in more than 50% of the population. Fine-needle aspiration cytology(FNAC) of thyroid nodules is a very useful diagnostic tool with high sensitivity and predictive value for diagnosis. The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) uses six categories for thyroid cytology reportin...

By Francesk Mulita, Fotios Iliopoulos, Christos Tsilivigkos, Levan Tchabashvili, Elias Liolis, Charalampos Kaplanis, Ioannis Perdikaris, Ioannis Maroulis

Aim To investigate the changes in the value of the signal to noise ratio (SNR) and to assess changes in the expression of nuclear factor erythroid 2-related factor 2 (NRF2) in the organ of Corti of rat exposed to noise.Methods This study used a randomized post test only control group laboratory experimental design with 27 male Wistar strain Rattus ...

By Diana Amellya, Tengku Siti Hajar Haryuna, Wibi Riawan

Aim To evaluate the pattern of indications and a spectrum of colonic pathology, and to determine appropriateness of indications for colonoscopy in order to improve patient selection for colonoscopy.Methods This retrospective study includes 294 patients who were referred to the Gastroenterology Department from a primary carephysician in order to app...

By Nerma Čustović, Lejla Džananović, Ismar Rašić, Nadža Zubčević, Lejla Šaranović-Čečo, Jasmina Redžepagić