Home Current Archive Editorial Team
About us
Aims and scope About Author Guidelines
News Contact
×
Home Current Archive Editorial board

Aims and scope About Author Guidelines
News Contact
Review paper
Received: 21.06.2019. >> Accepted: 04.07.2019. >> Published: 22.09.2019. Biochemistry
<< Prev | Next >>
PDF
https://doi.org/10.17392/1054-20

Epidemiology of measles cases and phylogenetic analysis of the virus circulated in the Federation of Bosnia and Herzegovina during 2018: implications for elimination efforts

By
Irma Salimović-Bešić Orcid logo ,
Irma Salimović-Bešić
Contact Irma Salimović-Bešić

Unit for Clinical Microbiology, Clinical Centre of the University of Sarajevo , Sarajevo , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar
Sanjin Musa ,
Sanjin Musa

Department of Epidemiology, Institute for Public Health of the Federation of Bosnia and Herzegovina , Sarajevo , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar
Nijaz Tihić ,
Nijaz Tihić

Department of Microbiology, Polyclinic for Laboratory Diagnostics, University Clinical Centre Tuzla , Tuzla , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar
Jurica Arapović ,
Jurica Arapović

Clinic for Infectious Diseases, University Clinical Hospital Mostar , Mostar , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar
Mirsada Hukić ,
Mirsada Hukić

Institute for Biomedical Diagnostics and Research Nalaz , Sarajevo , Bosnia and Herzegovina

Department of Medical Sciences, Academy of Sciences and Arts of Bosnia and Herzegovina , Sarajevo , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar
Mensura Šeremet ,
Mensura Šeremet

Unit for Clinical Microbiology, Clinical Centre of the University of Sarajevo , Sarajevo , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar
Edina Zahirović ,
Edina Zahirović

Unit for Clinical Microbiology, Clinical Centre of the University of Sarajevo , Sarajevo , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar
Suzana Arapčić ,
Suzana Arapčić

Unit for Clinical Microbiology, Clinical Centre of the University of Sarajevo , Sarajevo , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar
Amela Dedeić-Ljubović
Amela Dedeić-Ljubović

Unit for Clinical Microbiology, Clinical Centre of the University of Sarajevo , Sarajevo , Bosnia and Herzegovina

View authors publications

Search this author on:

PubMed | Google Scholar

Abstract

Aim
To present combined measles cases data and phylogenetic analysis of the virus circulated in 2018 in the Federation of Bosnia and Herzegovina (FB&H, the entity of Bosnia and Herzegovina), in order to analyse endemic transmission patterns of circulating strains and its implications for elimination efforts.
Methods
 The data were derived from epidemiological case investigations and laboratory diagnoses based on serology, molecular detection and genotyping of the measles virus.
Results
 During 2018 16 measles cases were reported in FB&H, of which five were classified as laboratory confirmed cases, one was an epidemiologically linked case and 10 were clinically compatible cases. Among them 12 (75.00%) cases were unvaccinated or had unknown vaccination status. The most affected population was up to 14 years of age (13/16; 81.25%). None of the cases was fully vaccinated. Viruses of other genetic lineages had been introduced in FB&H in the recent period. Two virus lineages of genotype B3 were identified. Phylogenetic analysis indicated the presence of a unique sequence of measles B3 virus in FB&H (Sarajevo).
Conclusion
 Further strengthening of measles surveillance system and renewed efforts to increase vaccination levels are necessary to prevent disease and for elimination setting.

Keywords:

genotype,
measles virus,
phylogeny,
vaccination,
virus diseases

References

1.
Kimura M. A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences. J Mol Evol. 1980;111–20.
2.
Tailoring immunization programmes to reach underserved groups -the TIP approach. 3AD;
3.
Institute for Public Health FB&H. Communication on the increase in the number of measles cases in neighboring countries. 2015;17–27.
4.
Hutchins S, Papania M, Amler R, Maes E, Grabowsky M, Bromberg K, et al. Evaluation of the Measles Clinical Case Definition. J Infect Dis. 2004;153–9.
5.
Surveillance Guidelines for Measles, Rubella and Congenital Rubella Syndrome in the WHO European Region, update December. 2012;
6.
Masresha B, Katsande R, Luce R, Fall A, Shibeshi M, Weldegebriel G, et al. Performance of National Measles Case-Based Surveillance Systems in The WHO African Region. 2012 -2016. J Immunol Sci. 2018;(019):130–4.
7.
Nsubuga F, Ampaire I, Kasasa S, Luzze H, Kisakye A. Positive predictive value and effectiveness of measles case-based surveillance in Uganda. PLoS One. 2012;184549.
8.
Turiac I, Fortunato F, Cappelli M, Morea A, Chironna M, Prato R, et al. Evaluation of measles and rubella integrated surveillance system in Apulia region, Italy, 3 years after its introduction. Epidemiol Infect. 2018;594–9.
9.
Vainio K, Steen T, Arnesen T, Rønning K, Ånestad G, Dudman S. Measles virus genotyping an important tool in measles outbreak investigation in Norway. Euro Surveill. 2011;20340.
10.
Epidemiological surveillance on communicable diseases in the Federation of Bosnia and Herzegovina. 2017;55.
11.
Hotchkiss D, Eisele T, Djibuti M, Silvestre E, Rukhadze N. Health system barriers to strengthening vaccine-preventable disease surveillance and response in the context of decentralization: evidence from Georgia. BMC Public Health. 2006;175.
12.
Masic I, Novo A, Pilav A, Jokić I, Toromanović S. Health Care System in Federation of Bosnia and Herzegovina. Mat Soc Med. 2006;212–8.
13.
Measles Nucleotide Surveillance (MeaNS) Database. 22AD;
14.
Measles virus nomenclature update: 2012. Wkly Epidemiol Rec. 2012;73–80.
15.
Seventh meeting of the European Regional Verification Commission for Measles and Rubella Elimination. :13–5.
16.
Saitou N, Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol. 1987;406–25.
17.
Kumar S, Stecher G, Tamura K, Mega. Molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol Biol Evol. 2016;1870–4.
18.
Hall T. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp Ser. 1999;95–8.
19.
Kremer J, Brown K, Santibanez J, Shulga S, Aboudy S, Demchyshyna Y, et al. High genetic diversity of measles virus, World Health Organization European Region. Emerg Infect Dis. 2008;107–14.
20.
Hukic M, Ravlija J, Karakas S, Mulaomerovic M, Ljubovic D, Salimovic-Besic A, et al. An ongoing measles outbreak in the Federation of Bosnia and Herzegovina. Euro Surveill. 2014;21047.
21.
Salimović-Bešić I, Šeremet M, Hübschen J, Hukić M, Tihić N, Ahmetagić S, et al. Dedeić-Ljubović A. Epidemiologic and laboratory surveillance of the measles outbreak in the Federation of Bosnia and Herzegovina. Clin Microbiol Infect. :563-e564.
22.
Аktuеlnа еpidеmiоlоšка situаciја mаlih bоginjа (mоrbilа) u Rеpublici Srbiјi. 22AD;
23.
Who Epidata. Data as of 05 July 2018. pdf. 2018;(6).
24.
Rota P, Brown K, Hübschen J, Muller C, Icenogle J, Chen M, et al. Improving global virologic surveillance for measles and rubella. J Infect Dis. 2011;(Suppl 1):506–13.
25.
Santibanez S, Hübschen J, Mamou B, Muscat M, Brown M, Myers K, et al. Molecular surveillance of measles and rubella in the WHO European Region: new challenges in the elimination phase. Clin Microbiol Infect. 2017;516–23.
26.
World Health Organization Measles Fact sheet.
27.
Eliminating measles and rubella -Framework for the verification process in the WHO European Region. 2014;

Citation

Copyright

Authors retain copyright. This work is licensed under a Creative Commons Attribution 4.0 International License. Creative Commons License

 

Article metrics

Google scholar: See link

{{ submission.title }}
Issue image
Vol 17, Issue 1, 2020
Digital dermatoglyphics in the evaluation of the genetic basis of breast cancer in Bosnian-Herzegovinian population - quantitative analysis Comparison of intubation condition and the quality of muscle relaxation between rocuronium and vecuronium using „timing principle“ Bone marrow adiposity is inversely associated with bone mineral density in postmenopausal females Fetuin-A Thr256Ser gene polymorphism as a mortality predictor in patients with chronic kidney disease on maintenance haemodialysis in Medan, Indonesia The relation between BRAFV600E mutation and clinicopathological characteristics of papillary thyroid cancer See full issue

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.