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Review paper

Results of bronchoscopic excision in typical carcinoid tumors of the lung in Turkey

By
Hilal Boyacı ,
Hilal Boyacı

Department of Chest Disease, Merzifon Karamustafa Paşa State Hospital, Amasya, Turkey

Mustafa Çörtük ,
Mustafa Çörtük
Contact Mustafa Çörtük

Department of Chest Disease, Karabuk University Medical School, Karabuk, Turkey

Şule Gül ,
Şule Gül

Department of Chest Disease, Yedikule Chest Diseases and Chest Surgery Education and Research Hospital, Istanbul, Turkey

Elif Tanrıverdi ,
Elif Tanrıverdi

Department of Chest Disease, Yedikule Chest Diseases and Chest Surgery Education and Research Hospital, Istanbul, Turkey

Mehmet Akif Özgül ,
Mehmet Akif Özgül

Department of Chest Disease, Yedikule Chest Diseases and Chest Surgery Education and Research Hospital, Istanbul, Turkey

Hüseyin Erhan Dinçer ,
Hüseyin Erhan Dinçer

Divisions of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, Minneapolis, United States

Erdoğan Çetinkaya
Erdoğan Çetinkaya

Department of Chest Disease, Yedikule Chest Diseases and Chest Surgery Education and Research Hospital, Istanbul, Turkey

Abstract

Aim
Carcinoid tumors of the lung are the tumors originating from the neuroendocrine cells. Surgical excision remains the gold standard for the treatment. Treatment with interventional bronchoscopic excision has also been reported as an alternative option in typical carcinoid tumors of the lung. The aim of this study was to present results and outcomes in patients who were bronchoscopically treated and followed-up.
Methods
Data of 14 patients, who had undergone bronchoscopic excision due to typical carcinoid tumor of the lung between April
2008 and July 2015 were retrospectively evaluated. Bronchoscopic excision procedures were performed under general anesthesia, while control bronchoscopies were carried out with flexible bronchoscopy. Time between the first and last bronchoscopies was accepted as the follow-up duration.
Results
A total of 14 patients was evaluated with eight (57.1%) males. Mean age was 43.57±14.07 (23-68) years. The most
common symptoms were shortness of breath and coughing. Mean of 5.69±3.35 (2-12) bronchoscopy procedures were performed in the patients during the diagnosis, treatment and follow-up. Mean follow-up duration was 32.0±19.22 months. At the long-term follow-up, two patients developed 50% stenosis and one patient developed granulation tissue in the endobronchial treatment site. None of the patients developed recurrence during the mean 32-month follow-up.
Conclusion
Endobronchial treatment is a safe and successful treatment method in well selected typical carcinoid tumor cases that
are centrally located, having no radiological suspicion of local or distant metastasis, distally visible but not located on the bronchi with a wide base on bronchoscopy. 

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