Aim To investigate etiological link between acute myocardial infarction (AMI) and the accompanying impotence/erectile dysfunction (ED). Methods Study included 99 male patients (48 who had AMI-patient group, and 51 healthy examinees without previous cardiovascular disease-control group). All patients completed a standardized questionnaire, the International Index of Erectile Function (IIEF-5). Results Older patients had significantly lower IIEF-5 score (negative correlation) (p <0.05), but higher ED degree (significant positive correlation) (rho=0.522; p=0.0001). In the patient group, 37 (77.1%) patients had ED, while in the control group it was found in 26 (51%) examinees (p<0.05). A clear correlation was found between incidence of ED and diabetes, dyslipidaemia, hypertension and positive family history (they were more common in patients with ED, with no statistically significant difference). There was no statistically significant difference between patients with ED and patients without ED according to the beta-blocker usage (p=0.824): ED was reported in 11 (68%) patients in the group who used carvedilol, 14 (82.3%) in the group who used metoprolol, and nine (81.8%) who used nebivolol. Conclusion Myocardial infarction as well as age are directly related to the occurrence of ED. Cardiovascular risk factors are in direct correlation for the occurrence of erectile dysfunction after myocardial infarction.
Maroto-Montero J, Portuondo-Maseda M, Lozano-Suárez M, Allona A, De Pablo-Zarzosa C, Morales-Durán M, et al. Erectile dysfunction in patients in a cardiac rehabilitation program. Rev Esp Cardiol. 2008;917–22.
2.
Lemogne C, Ledru F, Bonierbale M, Consoli S. Erectile dysfunction and depressive mood in men with coronary heart disease. Int J Cardiol. 2010;277–80.
3.
Kazemi-Saleh D, Pishgoo B, Farrokhi F, Fotros A, Assari S. Sexual function and psychological status among males and females with ischemic heart disease. J Sex Med. 2008;2330–7.
4.
Lunelli R, Rabello E, Stein R, Goldmeier S, Moraes M. Sexual activity after myocardial infarction: taboo or lack of knowledge. Arq Bras Cardiol. 2008;156–9.
5.
Cai X, Tian Y, Wu T, Cao CX, Bu SY, Wang KJ. The role of statins in erectile dysfunction: a systematic review and meta-analysis. Asian J Androl. 2014;461–6.
6.
Schwarz E, Kapur V. Erectile dysfunction in heart failure patients. J Am Coll Cardiol. 2006;1111–9.
7.
Fongemie J, Felix-Getzik E. A review of nebivolol pharmacology and clinical Evidence. Drugs. 2015;1349–71.
8.
Sharp R, Gales B. Nebivolol versus other beta blockers in patients with hypertension and erectile dysfunction. Ther Adv Urol. 2017;59–63.
9.
Frishman W, Henderson L, Lukas M. Controlled-release carvedilol in the management of systemic hypertension and myocardial dysfunction. Vasc Health Risk Manag. 2008;1387–400.
10.
Javaroni V, Neves M. Erectile dysfunction and hypertension: impact on cardiovascular risk and treatment. Int J Hypertens. 2012;627278.
11.
Dong J, Zhang Y, Qin L. Erectile dysfunction and risk of cardiovascular disease: meta-analysis of prospective cohort studies. J Am Coll Cardiol. 2011;1378–85.
12.
Andersson D, Lagerros T, Grotta Y, Bellocco A, Lehtihet R, Holzmann M, et al. Association between treatment for erectile dysfunction and death or cardiovascular outcomes after myocardial infarction. Heart. 2017;1264–70.
13.
Glavaš S, Valenčić L, Trbojević N, Tomašić A, Turčić N, Tibauth S, et al. Developing of psychological counselling may be of great importance. FUNDING No specific funding was received for this study. Acta Cardiol. 2015;712–9.
14.
Montorsi P, Ravagnani P, Galli S, Salonia A, Briganti A, Werba J, et al. Association between erectile dysfunction and coronary artery disease: Matching the right target with the right test in the right patient. Eur Urol. 2006;721–31.
15.
Araujo A, Mohr B, Mckinlay J. Changes in sexual function in middle-aged and older men: longitudinal data from the Massachusetts Male Aging Study. J Am Geriatr Soc. 2004;1502–9.
16.
Ruzic A, Persic E, Miletic B, Vcev A, Mirat J, Soldo I, et al. Erectile dysfunction after myocardial infarction -myth or a real problem? Coll Antropol. 2007;185–8.
17.
Rosen R, Riley A, Wagner G, Osterloh I, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997;822–30.
18.
Junuzovic D. Color doppler in evaluation of erectile dysfunction and its diagnostic value. Acta Inform Med. 2008;132–7.
19.
Sakka E, A. Erectile dysfunction, depression, and ischemic heart disease: Does the existence of one component of this triad necessitate inquiring the other two? J Sex Med. 2011;937–40.
20.
Carlsson A, Wändell P, Gigante B, Leander K, Hellenius M, De Faire U. Response to: modifiable lifestyle risks, cardiovascular disease, and all cause mortality. Int J Cardiol. 2014;560.
21.
Mollon L, Bhattacharjee S. Health related quality of life among myocardial infarction survivors in the United States: a propensity score matched analysis. Health Qual Life Outcomes. 2017;235.
22.
Menezes A, Artham S, Lavie C, Milani R, Keefe O, J. Erectile dysfunction and cardiovascular disease. Postgrad Med J. 2011;7–16.
The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.