Aim Despite many studies published in recent years concerning the relationship between demographic factors and varicocele, this issue remains controversial. The aim of this study was to identify a possible influence of body mass index (BMI) and height on occurrence varicocele in men. Methods In a case-control study 153 patients aged 18-40 years from 2004 to 20014, with moderate and sever varicocele were studied. The BMI and height of the 153 patients with varicocele were compared with 250 men who had no varicocele as a control group. Results After the adjustment for socio-demographic factors, the risk of varicocele for obese men was lower than for overweight and normal men (OR= 0.38, 95% CI= 0.17, 0.85). The adjusted OR for varicocele in taller men was higher than in those with low height (OR= 3.42, 95% CI= 1.34, 8.72), and moderate height (OR=2.68, 95% CI= 1.12, 6.46). Conclusion The results of this study indicated that tall men and non-obese men may be at higher risk of varicocele, therefore counseling and evaluation of the men at high risk of varicocele may be of benefit for reduced infertility.
Pasqualotto F, Pasqualotto E, Sobreiro B, Hallak J, Medeiros F, Lucon A. Clinical diagnosis in men undergoing infertility investigation in a university hospital. Urol Int 2006:122–5.
2
Maghraby H. Laparoscopic varicocelectomy for painful varicoceles: merits and outcomes. J Endourol 2002:107–10.
3
May M, Taymoorian K, Beutner S, Helke C, Braun K, Lein M, et al. Body size and weight as predisposing factors in varicocele. Scand J Urol Nephrol 2006:45–8.
4
Walters C, Marguet R, Crain C, D. Lower prevalence of varicoceles in obese patients found on routine scrotal ultrasound. J Urol 2012:599–601.
5
Delaney D, Carr M, Kolon T, Snyder H, Zderic S. The physical characteristics of young males with varicocele. BJU Int 2004:624–6.
6
Kilic S, Aksoy Y, Sincer I, Oguz F, Erdil N, Yetkin E. Cardiovascular evaluation of young patients with varicocele. Fertil Steril 2007:369–73.
7
Shamloul A-AB, Pichler R, M, Pummer A, K. Clinical and laboratory profiles of a large cohort of patients with different grades of varicocele. Cent European J Urol 2013:71–4.
8
Nielsen M, Zderic S, Freedland S, Jarow J. Insight on pathogenesis of varicoceles: relationship of varicocele and body mass index. Urology 2006:392–6.
9
Tsao C, Hsu C, Chou Y, Wu S, Sun G, Yu D, et al. The relationship between varicoceles and obesity in a young adult population. Int J Androl 2009:385–90.
10
Handel L, Shetty R, Sigman M. The relationship between varicoceles and obesity. J Urol 2006:2138–40.
11
Obesity: Identification, Assessment and Management of Overweight and Obesity in Children, Young People and Adults: Partial Update of CG43 2014:189.
12
Hauser R, Paz G, Botchan A, Yogev L, Yavetz H. Varicocele: effect on sperm functions. Hum Reprod Update 2001:482–5.
13
Soylemez H, Atar M, Sancaktutar A, Bozkurt A, Penbegul Y, N. Varicocele among healthy young men in Turkey; prevalence and relationship with body mass index. Int Braz J Urol 2012:116–21.
14
Baek M, Park S, Moon K, Chang Y, Jeong H, Lee S, et al. Nationwide survey to evaluate the prevalence of varicoceles in South Korean middle school boys: a population based study. Int J Urol 2011:55–60.
15
Chen S, Huang W. Differences in biochemical markers and body mass index between patients with and without varicocele. J Chin Med Assoc 2010:194–8.
16
Hassanzadeh K, Yavari-Kia P, Soleymanpour H, Ebrahimpour N, Alikhan H. Effect of body mass index and prevalence of varicocele. Pak J Biol Sci 2011:806–75.
17
Doğantekin E, Görgel S, Şahin E, Girgin C. Relationship between varicocele and anthropometric indices in infertile population. Dicle Medical Journal 2014:59–63.
18
Gokce A, Demirtas A, Ozturk A, Sahin N, Ekmekcioglu O. Association of left varicocoele with height, body mass index and sperm counts in infertile men. Andrology 2013:116–9.
19
Kumanov P, Robeva R, Tomova A. Adolescent varicocele: who is at risk? Pediatrics 2008:e53-57.
20
Rais A, Zarka S, Derazne E, Tzur D, Calderon-Margalit R, Davidovitch N, et al. Varicocoele among 1 300 000 Israeli adolescent males: time trends and association with body mass index. Andrology 2013:663–9.
21
Agarwal A, Sharma R, Desai N, Prabakaran S, Tavares A, Sabanegh E. Role of oxidative stress in pathogenesis of varicocele and infertility. Urology 2009:461–9.
22
Kwak N, Siegel D. Imaging and interventional therapy for varicoceles. Curr Urol Rep 2014:399.
23
Bozhedomov V, Lipatova N, Rokhlikov I, Alexeev R, Ushakova I, Sukhikh G. Male fertility and varicocoele: role of immune factors. Andrology 2014:51–8.
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