Effects of magnesium sulfate on airway smooth muscle contraction in rats
Aim To investigate the effect of magnesium sulfate (MgSO4) at different doses on isolated tracheal smooth muscle contraction in rats induced by different mechanisms.Methods Twelve rats’ tracheas were placed into organ bath. Consecutively, acetylcholine (10−6,10−5,10−4 M), histamine(10−8,10−5,10−3 M) and KCl...
By Hatice Betul Altinisik, Pakize Kirdemir, Ugur Altinisik, Osman Gokalp
Impact of timing on surgical outcome in patients with cauda equina syndrome caused by lumbar disc herniation
Aim To analyze the relationship between timing of surgery and outcome in patients with cauda equina syndrome caused by lumbar disc herniation.Methods A retrospective, non-randomized clinical study included 25 consecutive patients with cauda equina syndrome (CES) caused by lumbar disc herniation. All patients were operated within 24 hours after hosp...
By Hakija Bečulić, Rasim Skomorac, Aldin Jusić, Fahrudin Alić, Melica Imamović, Alma Mekić-Abazović, Alma Efendić, Harun Brkić, Amir Denjalić
Relation of red cell distribution width with dipper and non-dipper hypertension
Aim Red cell distribution width (RDW), an index of erythrocyte size, is associated with high risk for cardiovascular disease. Nondipping hypertension (HT) is lack of nocturnal fall in blood pressure (BP). The association between RDW and non-dipping BP in normotensive and hypertensive patients was investigated.Methods A total of 170 patients were ca...
By Eyup Buyukkaya, Ali Erayman, Esra Karakas, Alper Bugra Nacar, Mustafa Kurt, Sule Buyukkaya, Adnan Burak Akcay, Nihat Sen
Incidence of endophthalmitis after intravitreal application of anti VEGF therapy at the University Clinical Center in Tuzla, Bosnia and Herzegovina
Aim To report the incidence of endophthalmitis following the use of intravitreal injection of anti- vascular endothelial growth factor(anti VEGF) therapy.Methods In this retrospective study a total of 986 intravitreal bevacizumab injections were applied between January 2008 andApril 2015 at the University Clinical Center Tuzla, Bosnia and Herzegovi...
By Svjetlana Terzić, Adisa Pilavdžić, Amra Nadarević Vodenčarević
Possibilities of differentiation of solitary focal liver lesions by computed tomography perfusion
Aim To evaluate possibilities of computed tomography (CT) perfusion in differentiation of solitary focal liver lesions based ontheir characteristic vascularization through perfusion parameters analysis.Methods Prospective study was conducted on 50 patients in the period 2009-2012. Patients were divided in two groups: benignand malignant lesions. Th...
By Irmina Sefić Pašić, Anes Pašić, Spomenka Kristić, Adnan Beganović, Aladin Čarovac, Amra Dzananovic, Lidija Lincender, Sandra Vegar Zubović
Familial autoimmune thyroid disease and PTPN-22
Aim Autoimmune thyroid disease (AITD) is a multifactorial disease with a genetic predisposition. The protein tyrosine phosphatase-22 (PTPN-22) gene is a powerful inhibitor of T-cell activation. The aim of this study was to compare messenger RNA (mRNA) PTPN22 expression between healthy persons and patients with hypothyroidism and with their affected...
By Gabriel Conzuelo Rodríguez, Hugo Mendieta Zerón
Impact of reperfusion therapy and infarct localization on frequency of premature ventricular beats in acute myocardial infarction
Aim To determine the impact of infarct localization and types of reperfusion therapy on the frequency of ventricular premature beats (VPBs) in patients with acute myocardial infarction (AMI) and reduced left ventricular ejection fraction (LVEF). Methods A total of 705 patients with acute ST elevation myocardial infarction (STEMI) were divided accor...
By Davor Horvat, Josip Vincelj
Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina
AimRecently increased attention and interest for Acinetobacterbaumanniiare the result of the occurrence of multidrug resistant(MDR), extensive drug resistant (XDR) and pandrug resistant (PDR) isolates around the world. The aim of this study was to examine the resistance of A. baumannii isolates to antimicrobials in Clinical Centre University of Sar...
By Amela Dedeić-Ljubović, Đana Granov, Mirsada Hukić
Effects of post-sampling analysis time, type of blood samples and collection tubes on values of blood gas testing
Aim To investigate effects of post-sampling analysis time, a type of blood samples and collection tubes on blood gas testing.MethodsThis study included 100 patients at the Clinic for Pulmonary Diseases, Clinical Centre Sarajevo. The partial pressure ofoxygen (pO2) and carbon dioxide (pCO2), and the oxygen saturation level of hemoglobin (sO2) were a...
By Jasmina Smajić, Damira Kadić, Sabaheta Hasić, Nafija Serdarević
Differences in body mass index and height factors between men with and without varicocele
Aim Despite many studies published in recent years concerning the relationship between demographic factors and varicocele, this issue remains controversial. The aim of this study was to identify a possible influence of body mass index (BMI) and height on occurrence varicocele in men.Methods In a case-control study 153 patients aged 18-40 years from...
By Hamid Shafi, Mouloud Agajani Delavar