Aim. Colorectal cancer (CRC) ranks among the leading causes of cancer-related mortality worldwide, with significant incidence and mortality rates recorded in Kazakhstan. CRC poses a substantial healthcare burden, prompting investigations into novel prognostic markers. Aim. This study investigates the prognostic significance of CD163 expression in ...

By Nauryzbay Imanbayev, Yerbolat Iztleuov, Arip Koyshybaev, Aigul Zhumasheva, Beibit Baizakov, Nurgul Kereyeva, Zhanna Satenova, Aigerim Imanbayeva, Anara Tulyayeva, Dinara Zholmukhamedova, Marzhan Aitmagambetova, Azamat Zharylgapov

Aim Any aesthetic procedure in the head and/or in the face might have an impact on psychological status of the treated participants. Aim of this study was to investigate whether Botulinum toxin treatment for aesthetic purpose in the face influences on the level of happiness, depression and anxiety. Methods This prospective cohort observational stu...

By Omar Suljagić, Emir Tupković, Kenana Ljuca, Faris Suljagić, Nadina Ljuca

Aim To determine whether Ki67 can be predicted through its correlation with the estrogen receptor (ER) and progesterone receptor (PR), to identify breast cancer subtypes and evaluate cell proliferation level and prognosis. Methods Patient clinical data were collected from medical records and pathology laboratory reports at Teaching Hospital, Facul...

By Dedy Hermansyah, Muhammad Al Anas, Kania Haura Chalisaturahmi, Mutiara Baitina, Karina Sugih Arto, Endi Taris Pasaribu

ABSTRACT Aim This study compared the extent of coronary artery calcification in patients with and without type 2 diabetes mellitus (T2DM) using Coronary Computed Tomography Angiography (CCTA). Methods This retrospective, observational cohort study included 107 patients who underwent CCTA at the Clinical Centre of the University of Sarajevo betwee...

By Mirza Babić, Zarina Babić Jušić, Sabina Prevljak, Fuad Zukić, Minela Bećirović, Amir Bećirović, Admir Abdić, Emir Bećirović

Aim To assess Qualitiy of life (QoL) in adults by comparing two groups, the one with diagnosed hearing loss (HL) and the other without hearing complaints. Methods This cross-sectional study included 110 consecutive voluntary adult  patients divided in two groups: patients with hearing loss and control group. All participants , after examinati...

By Amel Krkalić, Admir Keserovic, Harun Selimović, Harun Mandra, Anes Jogunčić, Ragib Pugonja

Aim To systematically review the efficacy and safety of fixed-dose combination (FDC) antihypertensive agents in chronic kidney disease (CKD). Methods This systematic review included studies from January 2014 to December 2023 that evaluated FDC antihypertensives in CKD. We searched The PubMed, Embase, and the Cochrane Library databases were searche...

By Vedad Herenda, Selma Jusufović, Adnan Musanović

Aim To investigate the relationship between postoperative serum thyroglobulin level ​​and outcome of therapy with I-131 of follicular thyroid cancer. Methods A total of 106 patients with follicular thyroid cancer who were being treated and monitored at the Clinic for Nuclear Medicine at Clinical Center of the University of Sarajevo were included. ...

By selma Agić-Bilalagić, Šejla Cerić, Amela Begić, Azra Durak-Nalbantić, Edina Đozić, Timur Cerić

Aim Moderate to severe asthma patients with sufficient and insufficient vitamin D serum level, respectively, were assessed with quality of life questionnaires before and after treatment with vitamin D added to their standard asthma treatment.Methods Patients with moderate to severe asthma have been divided into two groups based on a serum level of ...

By Dzenan Halilovic, Jasmina Nurkić, Senahid Trnačević, Midhat Nurkić, Eldina Halilović, Ekrema Mujarić

Aim To confirm the effectiveness of the ActiPatch device in treating and preventing pillar pain following open carpal tunnel release surgery.Methods Ten elderly patients with pillar pain after carpal tunnel release surgery were treated with ActiPatch for seven days. When these patients underwent surgery on the opposite hand, they were pre-emptively...

By Giulia Maria Sassara, Adriano Cannella, Ludovico Caruso, Giuseppe Taccardo, Marco Passiatore, Arturo Militerno, Maurizio Marinangeli, Rocco De Vitis

Aim To assess the prevalence and risk factors associated with obstetric violence during childbirth among Jordanian women. Methods A descriptive cross-sectional design was adopted. Recruitment occurred in public maternity and children’s health centres in the Irbid Directorate in Jordan. Five hundred and fifteen women were enrolled in the ...

By Nour Alrida, Amal Ababneh, Muna Salahat, Yasmeen Abu-Sumaqa, Ahmad Rayan, Basheer Al-Zu'bi, Manar Abu-Abbas