Hypoxia-conditioned mesenchymal stem cells (MSC) exosomes attenuate ultraviolet-B (UVB)-mediated malondialdehyde (MDA) and matrix metalloproteinase-1 (MMP)-1 upregulation in collagen loss models
Aim To investigate the effects of exosome-derived human mesenchymal stem cells (EH-MSCs) on matrix metalloproteinase-1 (MMP)-1 and malondialdehyde (MDA) levels in ultraviolet-B (UVB)-irradiated Wistar rats.Methods The study used a post-test-only control group design with randomized allocation. Thirty rats were exposed to UVB radiation (302 nm, 150 ...
By Jessica Angelina, Agung Putra, Setyo Trisnadi, Dedy Hermansyah, Eko Setiawan, Titiek Sumarawati, Nur Dina Amalina
Clitorea ternatea flower extract induces platelet-derived growth factor (PDGF) and GPx gene overexpression in ultraviolet (UV) B irradiationinduced collagen loss
Aim To determine the effect of Clitorea ternatea flower extract (CTFE) in the gel dosage form on the expression of GPx and platelet-derived growth factor (PDGF) in ultraviolet (UV) - B irradiation-induced collagen loss rat model.Methods This is experimental research with post-test control group design. Twenty healthy male Wistar rats were divided i...
By Rizka Sofyanti Putri, Agung Putra, Dr Chodidjah, Dewi Masyitah Darlan, Setyo Trisnadi, Siti Thomas, Nur Dina Amalina, Rizky Candra Irawan