Rats’ umbilical-cord mesenchymal stem cells ameliorate mast cells and Hsp70 on ovalbumin-induced allergic rhinitis rats
Aim Allergic rhinitis (AR) is a heterogeneous condition that has been associated with inflammatory responses and is characterized by clinical typical symptoms of nasal itching, sneezing, watery discharge and congestion. Mesenchymal stem cells (MSCs) are multipotent stem cells that have the immunoregulatory ability by secreting various cytokines whi...
By Lia Restimulia, Syafruddin Ilyas, Delfitri Munir, Agung Putra, Teti Madiadipoera, Farhat Farhat, Rosita Juwita Sembiring, Muhammad Ichwan, Nur Dina Amalina
Combination of vitamin A and D supplementation for ischemic stroke: effects on interleukin-1ß and clinical outcome
Aim Accumulated evidence suggests that vitamin A and D agonists can alleviate the development of atherosclerosis. Therefore, the aim of this study was to determine the effect of vitamin A and D combination supplement on interleukin-1β (IL-1β) and clinical outcome in ischemic stroke. Methods A single-blind, randomized controlled trial was ...
By Alfansuri Kadri, Hasan Sjahrir, Rosita Juwita Sembiring, Muhammad Ichwan
Snakehead fish extract as an enhancer of vascular endothelial growth factor and nitric oxide levels in cerebral angiogenesis: an insight of stroke therapy
Aim To assess the effect of snakehead fish extract administration in angiogenesis focusing on the level of vascular endothelial growth factor (VEGF), nitric oxide (NO) and VEGF receptor 2 (R2) expression is ischemic stroke models. Methods An experimental study was conducted on 5 groups of ischemic stroke rats models: Group K-without carotid artery ...
By Iskandar Nasution, Hasan Sjahrir, Syafruddin Ilyas, Muhammad Ichwan