An ethanol extract of Senduduk fruit (Melastoma malabathricum L) inhibits the expression of vascular endothelial growth factor and tumour necrosis factor alpha in HeLa cells
Aim Senduduk fruit (Melastoma malabathricum L) is native to Indomalaya and is believed to possess anticancer activity. This study investigated antiangiogenic and anti-inflammation effects of an ethanolic extract of Senduduk fruit (EESF) on HeLa cells. Methods Cytotoxicity was assayed in HeLa cell cultures exposed to a concentration series of 500-7....
By Deri Edianto, Aznan Lelo, Syafruddin Ilyas, Marline Nainggolan
Poguntano effect on cell viability in cholesteatoma keratinocyte of chronic suppurative otitis media
Aim Chronic Suppurative Otitis Media (CSOM) with or without cholesteatoma is a global major problem and it is becoming a burden especially in developing countries. Studies have found that ethanol extracts of Puguntano leaves obtained by the percolation and socletation methods have phytochemical contents that provide anti-inflammatory effect. The ai...
By Harry A. Asroel, Aznan Lelo, Delfitri Munir, Jenny Bashiruddin, Restu Syamsul Hadi
A therapeutic effect of Nigella sativa extract on female Wistar rats vulvovaginal candidiasis model
Aim Vulvovaginal candidiasis (VVC) is a disease mostly caused by Candida albicans and affects the quality of life of women especially in the form of chronic recurrent vulvovaginal candidiasis (RVVC). Nigella sativa is known to have several effects such as antimicrobial, anti-inflammatory, immune stimulation and anticancer properties. The aim of thi...
By Muhammad Rusda, Muhammad Fidel Ganis Siregar, Aznan Lelo, Syafruddin Ilyas, Ratna Akbari Ganie, Yusuf Effendi, Poppy Anjelisa Zaitun Hasibuan, Raden Roro Lia Iswara