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University of Sarajevo , Sarajevo , Bosnia and Herzegovina
Department of Medical Biochemistry, Faculty of Medicine, University of Sarajevo , Sarajevo , Bosnia and Herzegovina
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Department for Blood-Borne Disease Testing, Blood Transfusion Institute of the Federation of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina , Sarajevo , Bosnia and Herzegovina
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Department of Medical Biochemistry, Faculty of Medicine, University of Sarajevo , Sarajevo , Bosnia and Herzegovina
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Department of Medical Biochemistry, Faculty of Medicine, University of Sarajevo , Sarajevo , Bosnia and Herzegovina
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Department of Human Physiology, Faculty of Medicine, University of Sarajevo , Sarajevo , Bosnia and Herzegovina
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Department of Medical Biochemistry, Faculty of Medicine, University of Sarajevo , Sarajevo , Bosnia and Herzegovina
Clinical Pathology and Cytology, University Clinical Centre Sarajevo , Sarajevo , Bosnia and Herzegovina
Aim. This study aimed to reveal the prevalence of the insulin resistance (IR) identified by triglyceride glucose index (TyG index) among students of University of Sarajevo. The impact of visceral fat level and waist to hip ratio measures on TyG value in students has been investigated. Patients and methods. Study included 160 apparently healthy students, both genders, aged from 19-27 years. Two groups were formed: Group1, TyG <4,49 and Group 2, TyG³4,49. A short interview, questionnaire, anthropometric measures, visceral fat level (VFL), blood pressure and biochemical parameters were applied. The statistical level of significance was P<0,05. Results. Forty-five students (28, 1%) were insulin resistant. There was a significant difference in TyG value (P<0,001), [group 1- 4,19 (3,93-4,34 vs. group 2 - 4,59 (4,55-4,74)]. Fasting blood glucose (FBG) and lipid parameters-total cholesterol, triglycerides and very low-density lipoprotein cholesterol (TC, TG and VLDL-C) were significantly higher in group TyG ³4,49 compared to TyG <4,49 group, with exception of HDL-C of LDL-C (P>0.05). Stepwise linear regression analysis showed significant impact of waist to hip ratio on TyG value (P=0,001). Conclusion. The prevalence of IR measured by TyG in university students was 28,1%. The impact of waist to hip ratio on value of TyG index points on possible application of both parameters in visceral obesity and insulin resistance assessment in apparently healthy individuals.
Conceptualization, S.H.; Funding acquisition, S.H.; Software, S.H.; Writing – original draft, S.H.; Methodology, A.Đ., E.K., R.J., L.M., A.T. and S.H.; Writing – review & editing, A.Đ., E.K., R.J., L.M. and S.H. All authors have read and agreed to the published version of the manuscript.
Conflict of interest: None to declare.
Federal Ministry of Education and Science, agreement number 05-35-2436-1/23, financially supported research project entitled: “Significance of triglyceride glucose index and lipid parameters in early detection of cardiovascular risk in students’ population”. This scientific publication resulted from the project and all authors would like to express their appreciation to the Federal Ministry of Education and Science of FB&H for support in this scientific project.
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