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Review paper

Brucellosis in children in Bosnia and Herzegovina in the period 2000 - 2013

By
Sead Ahmetagić ,
Sead Ahmetagić

Clinic for Infectious Diseases, University Clinical Centre Tuzla, Tuzla, Bosnia and Herzegovina

Humera Porobić-Jahić ,
Humera Porobić-Jahić
Contact Humera Porobić-Jahić

Clinic for Infectious Diseases, University Clinical Centre Tuzla, Tuzla, Bosnia and Herzegovina

Nada Koluder ,
Nada Koluder

Clinic for Infectious Diseases, University Clinical Centre Sarajevo, Sarajevo, Bosnia and Herzegovina

Lejla Čalkić ,
Lejla Čalkić

Department for Infectious Diseases, Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina

Snježana Mehanić ,
Snježana Mehanić

Clinic for Infectious Diseases, University Clinical Centre Sarajevo,, Sarajevo, Bosnia and Herzegovina

Eldira Hadžić ,
Eldira Hadžić

Department for Infectious Diseases, Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina

Nevzeta Ibrahimpašić ,
Nevzeta Ibrahimpašić

Department for Infectious Diseases, Cantonal Hospital Bihać, Bihać, Bosnia and Herzegovina

Svjetlana Grgić ,
Svjetlana Grgić

Clinic for Infectious Diseases, Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina

Mirela Zirić ,
Mirela Zirić

Department for Infectious Diseases, Cantonal Hospital Bihać, Bihać, Bosnia and Herzegovina

Jelena Bajić ,
Jelena Bajić

Clinic for Infectious Diseases, Clinical Center Banja Luka, Banja Luka, Bosnia and Herzegovina

Denis Žepić
Denis Žepić

Clinic for Infectious Diseases, University Clinical Centre Tuzla, Tuzla, Bosnia and Herzegovina

Abstract

Aim
To analyse clinical, laboratory and epidemiological characteristics of brucellosis in children in Bosnia and Herzegovina.
Methods
The study included 246 children aged 0-18 years, who were hospitalized in Clinics and Departments for Infectious Diseases in Tuzla, Sarajevo, Banja Luka, Zenica and Bihać in the period 2000-2013, in whom the diagnosis of brucellosis was established based on anamnestic data, clinical features and positive results from blood culture and/or positive results from one of the serological tests.
Results
In this period, a total of 2630 patients, 246 (9.35%) of whom were children, were treated from brucellosis at the Clinics and Departments in Bosnia and Herzegovina. In the majority of cases, the children were from rural parts of the country, 226
(91.87%);214 (87.04%) cases had direct contact with sick animals, sick family member or consumption of unpasteurized dairy products from farms where brucellosis had been already established. Male children predominated, 157 (63.82%). The most frequent clinical features in affected children were fever, 194 (78.86%) and joint pain, 158 (64.22%). The average duration of antimicrobial treatment was 42.85 ± 10.67 days. A total of 228 (92.68%) children were completely cured, while relapses occurred in 18 (7.32%) children.
Conclusion
Since brucellosis is an endemic disease in Bosnia and Herzegovina, it is important that physicians in their daily practice
consider brucellosis and establish proper diagnosis and therapy in children with prolonged fever, arthralgia, leukopenia and positive epidemiological data, especially in rural parts of the country.

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Ahmetagić1 S, Porobić-Jahić1 H. Lejla Čalkić 3 , Snježana Mehanić 2 , Eldira Hadžić 3 , Nevzeta Ibrahimpašić 4. Svjetlana Grgić. Denis Žepić1;
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Zaključak S obzirom da je bruceloza endemska bolest u Bosni i Hercegovini važno je da liječnici u svom svakodnevnom radu imaju na umu ovu bolest i postave pravu dijagnozu, te odgovarajući tretman djeci sa simptomima u vidu produžene temperature, artralgijama, leukopenijom i pozitivnom epidemiološkom dijagnozom, posebno u ruralnim dijelovima zemlje.

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