ABO groups as a risk factor for myocardial infarction in the population of Bosnia and Herzegovina

Ermina Mujičić; Nermir Granov; Armin Šljivo; Amina Selimović

doi:10.17392/1197-20

Review paper

Received: 04.05.2020. >> Accepted: 12.06.2020. >> Published: 12.07.2020. Biochemistry

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https://doi.org/10.17392/1197-20

ABO groups as a risk factor for myocardial infarction in the population of Bosnia and Herzegovina

Abstract

Aim
To investigate the association of ABO blood types and appearance of myocardial infarction (MI) among the population in Bosnia and Herzegovina.
Methods
This was a cross sectional study conducted at the Department for Cardiovascular Surgery at the Clinical Centre of the University of Sarajevo from January 1 st to December 31 st 2019. Patients were divided into two groups, defined by their blood type, A (N=91) and non-A (N=109). ABO blood groups were determined using standard agglutination techniques. Information regarding history of MI was taken from their medical documentation during the preparation for surgery.
Results
In total 200 patients were involved in this study. The study sample consisted of 151 (74.5%) males and 49 (25.5%) females. Mean age was 62.98 ± 7.73. Various risk factors associated with myocardial infarction were tobacco 92 (46.0%) and alcohol 54 (27.0%) consumption, obesity 77 (38.5%), diabetes mellitus 47 (23.5%) and hypertension 91 (45.3%). Being A blood type (OR=3.308; 95% Cl 1.317-8.311; p=0.011) and being male and having hypertension (OR=3.086; 95% Cl 1.262-7.545; p=0.013) significantly increased the risk for the development of MI among young adults. Patients with A blood type were significantly younger [median 58.0 vs. 63.0; U = 2738.5; p =0.027] when they developed MI compared to non-A blood type. Conclusion
The age of myocardial infarction occurrence in the population of Bosnia and Herzegovina is lower in patients with blood group A compared to non-A blood types.

Keywords:

acute myocardial infarction,

A blood type,

ABO blood groups,

coronary artery disease,

risk factors

References

Aa A-L, Bagger J, Albers C, Skinner J, Adams P, Hall R. A prospective study of long term prognosis in young myocardial infarction survivors: the prognostic value of angiography and exercise testing. Heart 2003:843–7.

Capuso E, Bonfanti C, Fratitini F, Montorosi P, Turdo R, Previdi M, et al. The relationship between ABO blood group and cardiovascular disease: results from the Cardiorisk program. Ann-Transi Med 2016:189–93.

Karabuva S, Carević V, Radić M, Fabijanić D. The association of ABO blood groups with extent of coronary atherosclerosis in Croatian patients suffering from chronic coronary artery disease. Biochem Med (Zagreb) 2013:351–9.

Jukic I, Bingulac-Popovic J, Dogic V, Babic I, Culej J, Tomicic M, et al. ABO blood groups and genetic risk factors for thrombosis in Croatian population. Croat Med J 2009:550–8.

Pisk S, Vuk T, Ivezić E, Jukić I, Bingulac-Popović J, Filipčić I. ABO blood groups and psychiatric disorders: Croatian study. Blood Transfus 2019:66–71.

Schwartz C, Mcmanus R. What is the evidence base for diagnosing hypertension and for subsequent blood pressure treatment targets in the prevention of cardiovascular disease? BMC Med 2015:256.

Kharroubi A, Darwish H. Diabetes mellitus: the epidemic of the century. World J Diabetes 2015:850–67.

Department, Health. HM Government 2016.

Kim H, Shin M, Roh J, Han M, Won Y, Cho I, et al. Association between cigarette smoking frequency and health factors among Korean adults. Iran J Public Health 2018;(Suppl 1):19–26.

Lisowska A, Makarewicz-Wujec M, Filipiak K. Risk factors, prognosis, and secondary prevention of myocardial infarction in young adults in Poland. Kardiol Pol 2016:1148–53.

Christiansen M, Larsen S, Nyegaard M, Neergaard-Peterson S, Würtz M, Grove E, et al. The ABO locus is associated with increased platelet aggregation in patients with stable coronary artery disease. Int J Cardiol 2019:152–8.

Huang X, Zou Y, Li L, Chen S, Hou J, Yu B. Relation of ABO blood groups to the plaque characteristic of coronary atherosclerosis. Biomed Res Int 2017:2674726.

Sari I, Ozer O, Davutoglu V, Gorgulu S, Eren M, Aksoy M. ABO blood group distribution and major cardiovascular risk factors in patients with acute myocardial infarction. Blood Coagul Fibrinolysis 2008:231–4.

Zhou B, Wu N, Zhu C, Gao Y, Guo Y, Qing P, et al. ABO blood group is a risk factor for coronary artery disease in patients with poor blood pressure control. Clin Exp Hypertens 2017:366–70.

Dentali F, Sironi A, Ageno W, Crestani S, Franchini M. ABO blood group and vascular disease: an update. Semin Thromb Hemost 2014:49–59.

Lee H, Lin Y, Lin C, Wang C, Chang C, Hsu L. Association of blood group A with coronary artery disease in young adults in Taiwan. Intern Med 2012:1815–20.

Hu X, Qiao S, Qiu H, Ye S, Feng L, Song L. Association between ABO blood group and acute myocardial infarction. Zhonghua Xin Xue Guan Bing Za Zhi 2015:785–7.