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Review paper

ABO groups as a risk factor for myocardial infarction in the population of Bosnia and Herzegovina

By
Ermina Mujičić Orcid logo ,
Ermina Mujičić
Contact Ermina Mujičić

Department of Cardiovascular surgery, Clinical Centre of the University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Nermir Granov ,
Nermir Granov

Department of Cardiovascular surgery, Clinical Centre of the University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Armin Šljivo ,
Armin Šljivo

School of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Amina Selimović
Amina Selimović

Department of Paediatrics, Clinical Centre of the University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Abstract

Aim
To investigate the association of ABO blood types and appearance of myocardial infarction (MI) among the population in Bosnia and Herzegovina.
Methods
This was a cross sectional study conducted at the Department for Cardiovascular Surgery at the Clinical Centre of the University of Sarajevo from January 1 st to December 31 st 2019. Patients were divided into two groups, defined by their blood type, A (N=91) and non-A (N=109). ABO blood groups were determined using standard agglutination techniques. Information regarding history of MI was taken from their medical documentation during the preparation for surgery.
Results
In total 200 patients were involved in this study. The study sample consisted of 151 (74.5%) males and 49 (25.5%) females. Mean age was 62.98 ± 7.73. Various risk factors associated with myocardial infarction were tobacco 92 (46.0%) and alcohol 54 (27.0%) consumption, obesity 77 (38.5%), diabetes mellitus 47 (23.5%) and hypertension 91 (45.3%). Being A blood type (OR=3.308; 95% Cl 1.317-8.311; p=0.011) and being male and having hypertension (OR=3.086; 95% Cl 1.262-7.545; p=0.013) significantly increased the risk for the development of MI among young adults. Patients with A blood type were significantly younger [median 58.0 vs. 63.0; U = 2738.5; p =0.027] when they developed MI compared to non-A blood type. Conclusion
The age of myocardial infarction occurrence in the population of Bosnia and Herzegovina is lower in patients with blood group A compared to non-A blood types.

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