Metabolic and renal predictors of coronary artery calcification: the independent role of the uric acid/estimated glomerular filtration rate (UA/eGFR) ratio and Castelli indices
ABSTRACT Aim To examine the association between metabolic parameters and novel cardiometabolic indices with the coronary artery calcium score (CACS). Methods: This retrospective cross-sectional study included 130 patients who underwent coronary computed tomography angiography (CCTA) at the Radiology Clinic of the Clinical Centre of the University...
By Zarina Babić Jušić, Mirza Babić, Sabina Prevljak, Emir Bećirović, Fuad Zukić, Minela Bećirović, Amir Bećirović
Laboratory parameters, clinical characteristics and hemogram-derived indices in adult patients with measles at tertiary hospital admission
Aim To describe the clinical picture and laboratory findings, as well as to examine the significance of novel hemogram-derived inflammatory indices in adult patients with measles admitted to a tertiary hospital. Methods This prospective, descriptive, and analytical study included adult patients over 18 years of age with clinical signs of measles, ...
By Berina Hasanefendić, Amila Muratspahić, Semir Hrvo, Emina Hajrović Hebibović, Lejla Avdagić, Almedina Moro, Emir Šeherčehajić, Amir Sandžić
Impact of 3D printing on vascular surgery training and preoperative planning
Aim: To investigate the impact of three-dimensional (3D) printing technology on vascular surgery, focusing on its role in preoperative planning and surgical training. Methods: A systematic review was conducted of studies published between 2017 and 2024 that evaluated 3D printing in vascular surgery. Databases searched included MEDLINE an...
By Haris Vukas, Samra Kadić-Vukas, Sumeja Ćatić, Ruvejda Dizdarević, Farah Dedović, Nail Šehić, Merim Jusufbegović
Effects of Lactobacillus rhamnosus probiotic supplementation on gut health in rabbits
Aim: The research examined the effects of prolonged oral Lactobacillus rhamnosus intake on rabbit intestinal tissue morphology. Methods: The study included twelve male rabbits aged 10–12 months and weighing 1.5–2.0 kg who received random assignment to two groups of six animals each. The control group received distilled water but the ex...
By Taghreed AL-fakje, Faeha Al-Mashhadane, ِAsmaa Al-Nuaimy
Continuous positive airway pressure failure in the management of neonatal respiratory distress in a resource limited setting: a prospective observational study
Aim To determine the frequency and identify predictors of Continuous positive airway pressure (CPAP) failure in neonates of varying gestational ages in a resource-limited setting, where CPAP is often used beyond the preterm population. Methods prospective observational study of 119 neonates started on CPAP within 24 hours of birth for respiratory ...
By Noor Sameer Yahya, Ahmed Khalil Ibrahim, AWS AL-NUMAN
Molecular docking analysis of thymoquinone as a potential inhibitor of C-reactive protein and transforming growth factor β (TGF-β): an in-silico study for myocardial infarction therapeutics
Abstract Background: Myocardial infarction (MI) is a cardiovascular disease that is the leading cause of death at all ages. Inflammation and oxidation processes constitute the basic pathophysiology of MI development. C-reactive protein (CRP) and transforming growth factor β (TGF-β) are markers that are often used to evaluate the level of...
By Muhammad Saugi Abduh, Ahmad Umar Alfaruq, Muh Adytia Prasada, Dimas Nabih
The correlation between interleukin-6 levels and quality of life in late-stage breast cancer patients with anxiety syndrome at Haji Adam Malik General Hospital, Medan
Aim: Breast cancer is the most common cancer found in women including in Indonesia. Breast cancer patients are prone to have anxiety and it affects their quality of life. Interleukin-6 (IL-6) is one of the pro-tumorigenic cytokines that increases in breast cancer and is associated with worse prognosis and cancer metastasis. Several studies demonstr...
By Ella Yunita Daulay, Mustafa Mahmud Amin, Elmeida Effendy, Vita Camellia, Kamal Basri Siregar
Elevated neutrophil-to-lymphocyte ratio predicts poorer histopathological differentiation in colorectal cancer: a study from a Southeast Asian Tertiary Hospital
Aim of this study was to evaluate the correlation between pre-treatment NLR and histopathological differentiation in colorectal cancer, and to assess the diagnostic accuracy of NLR as a predictive biomarker. Methods A retrospective study was conducted at Adam Malik Haji Center General Hospital Medan, North Sumatera. Medical records of 45 colorecta...
By Edwin Saleh Siregar, Muhammad Al Anas, Dedy Hermansyah
The significance of individual patient characteristics in a cohort of patients with inflammatory bowel disease treated with vedolizumab
Aim Care for the inflammatory bowel disease (IBD) patients presents unique challenges as decisions regarding therapy must consider numerous distinct characteristics of each patient. The aim of the study was to recognize patients’ characteristics as predictors of success in vedolizumab treatment.Methods In a retrospective observational study, ...
By Nadža Zubčević, Mirela Bašić-Denjagić, Emil Babić, Tatjana Barač, Aida Saray, Nerma Čustović
Knowledge and practice of intermittent fasting: a cross-sectional study among university students in the United Arab Emirates
Aim Intermittent fasting is a popular weight loss strategy that alternates between fasting periods and unrestricted eating. Research shows it can improve insulin resistance, lower HbA1c level, aid in weight management, and enhance cardiometabolic health. These effects can help address obesity, hypertension, and type 2 diabetes. Despite its populari...
By Sarah Imran Zahid, Mahnoor Dilawar, Fatima Garba Tahir, Tala Tarek Mousa, Nadia Imran Zahid, Jayadevan Sreedharan