Effect of vitamin D supplementation on metabolic syndrome and atherosclerosis biomarkers in epilepsy: a randomized controlled trial
Aim To analyze the effect of vitamin D administration on serum 25(OH)D levels and biomarkers of metabolic syndrome and atherosclerosis (homeostatic model assessment of insulin resistance [HOMA-IR], adiponectin, homocysteine, and high sensitivity C-reactive protein [hs-CRP]) in epilepsy patients receiving enzymatic antiseizure medications (ASMs). M...
By Sri Handayani, Zen Hafy, Fitri Octaviana, Zulkhair Ali, Nita Parisa, Astri Budikayanti, Dessy Agustini, Radiyati Umi Partan
Prophylactic use of rectal diclofenac in mitigating post endoscopic retrograde cholangiopancreatography pancreatitis risk and severity: low- vs high-dose efficacy and timing strategies— a meta-analysis
Aim Post endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most prevalent adverse event with significant morbidity following ERCP. Several guidelines have suggested the use of rectal diclofenac as a promising option to prevent PEP. Nonetheless, the recommended optimal dose and timing of administration remain unclear. T...
By Maggie Liberty, Taufik Sungkar, Peggy Liberty
Knowledge of general medicine students from the medical faculties in Tuzla and Zenica about lung cancer prevention
Aim To assess the level of knowledge about risk factors and prevention of lung cancer among medical students, and to identify differences in knowledge based on the year of study and previous secondary education background. Methods The study was conducted among 223 students of the School of Medicine, University of Zenica, and the School of Medicine...
By Amar Terzimehić, Elma Kuduzović, Nino Hasanica, Muhamed Skomorac, Erna Terzić, Iman Kovač
Evaluation of brain injury biomarkers in mild traumatic brain injury with and without computed tomography findings
Aim Mild traumatic brain injury (mTBI) presents diagnostic challenges, with head computed tomography (head CT) often overutilized in emergency settings. Blood biomarkers such as glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) have shown promise in early injury detection. Aim of this study was to evaluate ...
By Alma Osmić-Husni, Radivoj Jadrić, Svetlana Jović- Lacković, Aida Žabić, Sabina Čamdžić-Smajić
An animal model in rat for secondary osteoporosis: the effect of gonadotropin-releasing hormone (GnRH) agonists, low calcium diet, and immobilization on tartrate-resistant acid phosphatase 5b (TRACP-5b) and procollagen type 1 N-terminal propeptide (PINP) levels
Aim Osteoporosis is a global health concern, characterized by reduced bone density, microarchitectural changes, and an increased risk of fractures. The prevalence of osteoporosis is rising, particularly in developing countries. In Indonesia, the incidence of upper femur fractures due to osteoporosis is notably high. As human studies are limited, an...
By Panji Sananta, Respati Suryanto Dradjat, Istan Irmansyah Irsan, Andhika Yudistira, Aditya Rosid Dwi Anwar
Impact of 3D printing on vascular surgery training and preoperative planning
Aim: To investigate the impact of three-dimensional (3D) printing technology on vascular surgery, focusing on its role in preoperative planning and surgical training. Methods: A systematic review was conducted of studies published between 2017 and 2024 that evaluated 3D printing in vascular surgery. Databases searched included MEDLINE an...
By Haris Vukas, Samra Kadić-Vukas, Sumeja Ćatić, Ruvejda Dizdarević, Farah Dedović, Nail Šehić, Merim Jusufbegović
Laboratory parameters, clinical characteristics and hemogram-derived indices in adult patients with measles at tertiary hospital admission
Aim To describe the clinical picture and laboratory findings, as well as to examine the significance of novel hemogram-derived inflammatory indices in adult patients with measles admitted to a tertiary hospital. Methods This prospective, descriptive, and analytical study included adult patients over 18 years of age with clinical signs of measles, ...
By Berina Hasanefendić, Amila Muratspahić, Semir Hrvo, Emina Hajrović Hebibović, Lejla Avdagić, Almedina Moro, Emir Šeherčehajić, Amir Sandžić
Molecular docking analysis of thymoquinone as a potential inhibitor of C-reactive protein and transforming growth factor β (TGF-β): an in-silico study for myocardial infarction therapeutics
Abstract Background: Myocardial infarction (MI) is a cardiovascular disease that is the leading cause of death at all ages. Inflammation and oxidation processes constitute the basic pathophysiology of MI development. C-reactive protein (CRP) and transforming growth factor β (TGF-β) are markers that are often used to evaluate the level of...
By Muhammad Saugi Abduh, Ahmad Umar Alfaruq, Muh Adytia Prasada, Dimas Nabih
Risk factors for red blood cell alloimmunization in polytransfused patients
ABSTRACT Aim Alloimmunization depends on the type of the erythrocyte antigen, as well as the number of transfused doses of blood and recipient factors reflected in genetic and immunological status, comorbidities and therapy. The aim was to determine the frequency and type of antierythrocyte antibodies, to examine the correlation between the number...
By Svetlana Jović Lacković, Almira Ćosićkić
Comparative evaluation of HbA1c in point-of-care testing (POCT) devices: enzymatic and immunoassay methods compared to ion-exchange high-performance liquid chromatography (IE-HPLC)
Aim To evaluate 3 point-of-care testing (POCT) devices in testing HbA1c: the Simplex TASTM101 (Tascom Co. Ltd., South Korea), which utilizes an enzymatic method, and two immunoassay-based devices, the Zybio Q8 Pro and Zybio EXR 110 (Zybio Inc., China). Methods A total of 40 whole blood samples with EDTA anticoagulant were collected patients underg...
By Windradini Rahvian Aridama, Ferdy Royland Marpaung, Yessy Puspitasari