Effect of vitamin D supplementation on metabolic syndrome and atherosclerosis biomarkers in epilepsy: a randomized controlled trial
Aim To analyze the effect of vitamin D administration on serum 25(OH)D levels and biomarkers of metabolic syndrome and atherosclerosis (homeostatic model assessment of insulin resistance [HOMA-IR], adiponectin, homocysteine, and high sensitivity C-reactive protein [hs-CRP]) in epilepsy patients receiving enzymatic antiseizure medications (ASMs). M...
By Sri Handayani, Zen Hafy, Fitri Octaviana, Zulkhair Ali, Nita Parisa, Astri Budikayanti, Dessy Agustini, Radiyati Umi Partan
Prophylactic use of rectal diclofenac in mitigating post endoscopic retrograde cholangiopancreatography pancreatitis risk and severity: low- vs high-dose efficacy and timing strategies— a meta-analysis
Aim Post endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most prevalent adverse event with significant morbidity following ERCP. Several guidelines have suggested the use of rectal diclofenac as a promising option to prevent PEP. Nonetheless, the recommended optimal dose and timing of administration remain unclear. T...
By Maggie Liberty, Taufik Sungkar, Peggy Liberty
Knowledge of general medicine students from the medical faculties in Tuzla and Zenica about lung cancer prevention
Aim To assess the level of knowledge about risk factors and prevention of lung cancer among medical students, and to identify differences in knowledge based on the year of study and previous secondary education background. Methods The study was conducted among 223 students of the School of Medicine, University of Zenica, and the School of Medicine...
By Amar Terzimehić, Elma Kuduzović, Nino Hasanica, Muhamed Skomorac, Erna Terzić, Iman Kovač
Evaluation of brain injury biomarkers in mild traumatic brain injury with and without computed tomography findings
Aim Mild traumatic brain injury (mTBI) presents diagnostic challenges, with head computed tomography (head CT) often overutilized in emergency settings. Blood biomarkers such as glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) have shown promise in early injury detection. Aim of this study was to evaluate ...
By Alma Osmić-Husni, Radivoj Jadrić, Svetlana Jović- Lacković, Aida Žabić, Sabina Čamdžić-Smajić
An animal model in rat for secondary osteoporosis: the effect of gonadotropin-releasing hormone (GnRH) agonists, low calcium diet, and immobilization on tartrate-resistant acid phosphatase 5b (TRACP-5b) and procollagen type 1 N-terminal propeptide (PINP) levels
Aim Osteoporosis is a global health concern, characterized by reduced bone density, microarchitectural changes, and an increased risk of fractures. The prevalence of osteoporosis is rising, particularly in developing countries. In Indonesia, the incidence of upper femur fractures due to osteoporosis is notably high. As human studies are limited, an...
By Panji Sananta, Respati Suryanto Dradjat, Istan Irmansyah Irsan, Andhika Yudistira, Aditya Rosid Dwi Anwar
Advanced volar locking plate fixation for intra and extra articular distal radius fractures: a retrospective study
Background Distal radius fractures are among the most common orthopedic injuries, posing significant challenges due to their high prevalence and potential for long-term functional impairment. Volar locking plates have emerged as the gold standard for managing unstable and extra-articular fractures, offering superior outcomes compared to traditiona...
By Giuseppe Rovere, Francesco Bosco, Giulio Vigni, Ennio Sinno, Andrea Perna, Fortunato Giustra, Francesco Liuzza, Amarildo Smakaj, Fernando De Maio, Antonio Ziranu, Giuseppe Tulumello, Lawrence Camarda
Artificial intelligence and big data applications in chronic disease management: clinical outcomes, challenges, and future directions
Aim: To synthesize applications of Artificial Intelligence (AI) and big data in chronic disease management, evaluate clinical and economic outcomes, challenges, and future directions. Methods: A comprehensive search was conducted across PubMed, Scopus, Web of Science, IEEE Xplore, and CINAHL for studies published between 2015-2025, following the P...
By Sana'a Abu-Qbeitah, Muayyad Ahmad
Impact of donor and procedural parameters on platelet yield in plateletpheresis: a retrospective data analysis over a seven-month period
Aim: To identify the donor and procedural parameters that influence the platelet yield obtained by apheresis. Methods: A retrospective observation study of 60 plateletpheresis in the Blood Transfusion Institute of Federation of Bosnia and Herzegovina in Sarajevo, was done. Plateletpheresis were performed using Amicus cell separator with platelet c...
By Gorana Ahmetovic-Karic, Kenan Mehic, Selim Arifovic, Ajsa Zildzic, Faruk Bradaric
Risk factors for red blood cell alloimmunization in polytransfused patients
ABSTRACT Aim Alloimmunization depends on the type of the erythrocyte antigen, as well as the number of transfused doses of blood and recipient factors reflected in genetic and immunological status, comorbidities and therapy. The aim was to determine the frequency and type of antierythrocyte antibodies, to examine the correlation between the number...
By Svetlana Jović Lacković, Almira Ćosićkić
Comparative evaluation of HbA1c in point-of-care testing (POCT) devices: enzymatic and immunoassay methods compared to ion-exchange high-performance liquid chromatography (IE-HPLC)
Aim To evaluate 3 point-of-care testing (POCT) devices in testing HbA1c: the Simplex TASTM101 (Tascom Co. Ltd., South Korea), which utilizes an enzymatic method, and two immunoassay-based devices, the Zybio Q8 Pro and Zybio EXR 110 (Zybio Inc., China). Methods A total of 40 whole blood samples with EDTA anticoagulant were collected patients underg...
By Windradini Rahvian Aridama, Ferdy Royland Marpaung, Yessy Puspitasari