Effect of vitamin D supplementation on metabolic syndrome and atherosclerosis biomarkers in epilepsy: a randomized controlled trial
Aim To analyze the effect of vitamin D administration on serum 25(OH)D levels and biomarkers of metabolic syndrome and atherosclerosis (homeostatic model assessment of insulin resistance [HOMA-IR], adiponectin, homocysteine, and high sensitivity C-reactive protein [hs-CRP]) in epilepsy patients receiving enzymatic antiseizure medications (ASMs). M...
By Sri Handayani, Zen Hafy, Fitri Octaviana, Zulkhair Ali, Nita Parisa, Astri Budikayanti, Dessy Agustini, Radiyati Umi Partan
Evaluation of brain injury biomarkers in mild traumatic brain injury with and without computed tomography findings
Aim Mild traumatic brain injury (mTBI) presents diagnostic challenges, with head computed tomography (head CT) often overutilized in emergency settings. Blood biomarkers such as glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) have shown promise in early injury detection. Aim of this study was to evaluate ...
By Alma Osmić-Husni, Radivoj Jadrić, Svetlana Jović- Lacković, Aida Žabić, Sabina Čamdžić-Smajić
An animal model in rat for secondary osteoporosis: the effect of gonadotropin-releasing hormone (GnRH) agonists, low calcium diet, and immobilization on tartrate-resistant acid phosphatase 5b (TRACP-5b) and procollagen type 1 N-terminal propeptide (PINP) levels
Aim Osteoporosis is a global health concern, characterized by reduced bone density, microarchitectural changes, and an increased risk of fractures. The prevalence of osteoporosis is rising, particularly in developing countries. In Indonesia, the incidence of upper femur fractures due to osteoporosis is notably high. As human studies are limited, an...
By Panji Sananta, Respati Suryanto Dradjat, Istan Irmansyah Irsan, Andhika Yudistira, Aditya Rosid Dwi Anwar
Von Mises stress analyses using finite element model in two patients with chronic low back pain
Aim To investigate biomechanical properties of low back pain, which is a pervasive issue with a profound impact on an individual's quality of life due to pain and daily activity limitations. Methods Two female patients suffering from chronic low back pain were presented. Patient 1 had severe compression fractures at L2 and L4, while Patient 2 had ...
By Arief Indra Perdana Prasetya, Tri Indah Winarni, Jamari Jamari, Ardiyansyah Syahrom
Comparative evaluation of HbA1c in point-of-care testing (POCT) devices: enzymatic and immunoassay methods compared to ion-exchange high-performance liquid chromatography (IE-HPLC)
Aim To evaluate 3 point-of-care testing (POCT) devices in testing HbA1c: the Simplex TASTM101 (Tascom Co. Ltd., South Korea), which utilizes an enzymatic method, and two immunoassay-based devices, the Zybio Q8 Pro and Zybio EXR 110 (Zybio Inc., China). Methods A total of 40 whole blood samples with EDTA anticoagulant were collected patients underg...
By Windradini Rahvian Aridama, Ferdy Royland Marpaung, Yessy Puspitasari
Seroprevalence of Helicobacter pylori in Bosnia and Herzegovina: a single-center cross-sectional study
Aim Many studies have demonstrated that over half of the World's population is infected with Helicobacter pylori (H. pylori). To evaluate the current H. pylori seroprevalence in Bosnia and Herzegovina (B&H), H. pylori antibodies (immunoglobulin G, IgG) from patients with suspected presence were analyzed. Methods In total, 201/471 (42.7%) males...
By Nejra Bektaš, Larisa Bešić, Aida Kulo Ćesić, Damir Marjanović, Jasminka Prguda-Mujić
Evaluation of predictive factors for conception after saline infusion sonosalpingography
Objective: For evaluation of predictive factors of sponataneous conception after saline infused sonosalpingography (SIS). Method: A prospective study was conducted from August 2023 to December 2024 at reproductive medial unit at Mosul/Iraq. 100 women were recruited and categorized in to two groups: pregnant after SIS ...
By Dalal Ramadhan, MARWA AL-Rasheedy, Luma Alsarraj
Artificial intelligence and big data applications in chronic disease management: clinical outcomes, challenges, and future directions
Aim: To synthesize applications of Artificial Intelligence (AI) and big data in chronic disease management, evaluate clinical and economic outcomes, challenges, and future directions. Methods: A comprehensive search was conducted across PubMed, Scopus, Web of Science, IEEE Xplore, and CINAHL for studies published between 2015-2025, following the P...
By Sana'a Abu-Qbeitah, Muayyad Ahmad
Prophylactic use of rectal diclofenac in mitigating post endoscopic retrograde cholangiopancreatography pancreatitis risk and severity: low- vs high-dose efficacy and timing strategies— a meta-analysis
Aim Post endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most prevalent adverse event with significant morbidity following ERCP. Several guidelines have suggested the use of rectal diclofenac as a promising option to prevent PEP. Nonetheless, the recommended optimal dose and timing of administration remain unclear. T...
By Maggie Liberty, Taufik Sungkar, Peggy Liberty
Knowledge of general medicine students from the medical faculties in Tuzla and Zenica about lung cancer prevention
Aim To assess the level of knowledge about risk factors and prevention of lung cancer among medical students, and to identify differences in knowledge based on the year of study and previous secondary education background. Methods The study was conducted among 223 students of the School of Medicine, University of Zenica, and the School of Medicine...
By Amar Terzimehić, Elma Kuduzović, Nino Hasanica, Muhamed Skomorac, Erna Terzić, Iman Kovač