Aim To analyze the effect of vitamin D administration on serum 25(OH)D levels and biomarkers of metabolic syndrome and atherosclerosis (homeostatic model assessment of insulin resistance [HOMA-IR], adiponectin, homocysteine, and high sensitivity C-reactive protein [hs-CRP]) in epilepsy patients receiving enzymatic antiseizure medications (ASMs). M...

By Sri Handayani, Zen Hafy, Fitri Octaviana, Zulkhair Ali, Nita Parisa, Astri Budikayanti, Dessy Agustini, Radiyati Umi Partan

Aim:Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm of intermediate biological potential, characterized by spindle cell proliferation and significant inflammatory component. This study aimed to determine the clinicopathologic characteristics, the clinical outcomes of inflammatory myofibroblastic tumor cases in the low-volume...

By Asmir Jonuzi, Ilhana Tinjak, Melika Bukvic, Benjamin Kulovac, Nusret Popovic, Emir Milisic, Zlatan Zvizdic

Aim Teriparatide, a synthetic analog of the active fragment of human parathyroid hormone (PTH 1–34), is a clinically approved anabolic treatment for osteoporosis. While its bone-forming capacity is well-documented, evidence regarding its systemic safety, particularly in relation to male reproductive health, remains limited. Aim: This study w...

By Omar Ameen, Ghada Taqa

ABSTRACT Aim Alloimmunization depends on the type of the erythrocyte antigen, as well as the number of transfused doses of blood and recipient factors reflected in genetic and immunological status, comorbidities and therapy. The aim was to determine the frequency and type of antierythrocyte antibodies, to examine the correlation between the number...

By Svetlana Jović Lacković, Almira Ćosićkić

Aim Mild traumatic brain injury (mTBI) presents diagnostic challenges, with head computed tomography (head CT) often overutilized in emergency settings. Blood biomarkers such as glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) have shown promise in early injury detection. Aim of this study was to evaluate ...

By Alma Osmić-Husni, Radivoj Jadrić, Svetlana Jović- Lacković, Aida Žabić, Sabina Čamdžić-Smajić

Aim Osteoporosis is a global health concern, characterized by reduced bone density, microarchitectural changes, and an increased risk of fractures. The prevalence of osteoporosis is rising, particularly in developing countries. In Indonesia, the incidence of upper femur fractures due to osteoporosis is notably high. As human studies are limited, an...

By Panji Sananta, Respati Suryanto Dradjat, Istan Irmansyah Irsan, Andhika Yudistira, Aditya Rosid Dwi Anwar

Aim To compare outcomes and minimal clinically important differences (MCID) between single-level laminectomy (SLL) and two-level laminectomy (TLL) for lumbar spinal stenosis (LSS). Methods This prospective study included 119 patients with confirmed LSS who underwent SLL or TLL at Cantonal Hospital Zenica from January 2018 to January 2025. Assessme...

By Emir Begagić, Hakija Bečulić, Fahrudin Alić, Anes Mašović, Goran Lakičević, Lemana Buljubašić, Muhamed Haračić

Aim Metacarpal fractures are common hand injuries, frequently treated with closed reduction and internal fixation (CRIF) using Kirschner wires (K-wires). While exposed K-wires allow for simple hardware removal and early mobilization, their use is traditionally associated with a higher risk of pin tract infections. There is a lack of studies f...

By Andrea Cruciani, Silvia Pietramala, Alessio Greco, Alessandro El motassime, Camillo Fulchignoni, Lorenzo Rocchi

Aim Unintended scaphoid excision is a rare but serious complication that can occur during surgical procedures involving the trapezium, including but not limited to trapeziectomy. Although prosthetic replacement is increasingly favored in the treatment of rhizarthrosis, trapeziectomy (with or without ligamentoplasty) remains a widely used and effect...

By Camillo Fulchignoni, Silvia Pietramala, Chiara Muci, Alessandro El Motassime, Andrea Cruciani, Lorenzo Rocchi, Gianfranco Merendi

Aim To demonstrate the possibilities of reconstructing a prosthetic stump in a complex defect using staged osteotomy and lengthening, since for successful prosthetic replacement of the tibial stump, its sufficient length is necessary, which is not always possible. Methods In this article, we present a 25-year-old man diagnosed with a non-prostheti...

By Yurii Oleksiiovych Bezsmertnyi, Viktor Ivanovych Shevchuk, Olexander Yuriyovych Branitsky, Olexander Yuriyovych Bezsmertnyi, Dmytro Vadymovych Bondarenko