Effects of semi-refined carrageenan (food additive E407a) on cell membranes of leukocytes assessed in vivo and in vitro
Aim To assess the impact of semi-refined carrageenan (E407a) on hydrophobic regions of phosphololipid bilayer in cell membranes of leukocytes collected from rats orally administered this food additive and white blood cells incubated with E407a.Methods Fluorescent probes (ortho-hydroxy derivatives of 2,5-diaryl-1,3-oxazole) were used to estimate the...
By Anton Tkachenko, Anatolii Onishchenko, Alexander Roshal, Oksana Nakonechna, Tetyana Chumachenko, Yevgen Posokhov
Treatment effectiveness and outcome in patients with a relapse and newly diagnosed multidrug-resistant pulmonary tuberculosis
Aim To investigate the treatment effectiveness and outcome in patients with pulmonary tuberculosis relapse and newly diagnosed multidrug resistant pulmonary tuberculosis (MDR-TB). Methods A total of 240 pulmonary MDR-TB patients, including 114 ones with tuberculosis relapse and 126 cases of newly diagnosed pulmonary tuberculosis, were examined. Eff...
By Dmytro Butov, Valeriy Myasoedov, Mykola Gumeniuk, Galyna Gumeniuk, Oleksandra Choporova, Anton Tkachenko, Oleksandra Akymenko, Olena Borysova, Olena Goptsii, Yevhenii Vorobiov, Tetiana Butova
A study of enterocyte membranes during activation of apoptotic processes in chronic carrageenan–induced gastroenterocolitis
Aim To investigate the lipid membranes of rat enterocytes in chronic carrageenan-induced gastroenterocolitis accompanied by the activation of apoptotic processes. Methods Steady-state fluorescence spectroscopy: a study by fluorescent probes-by ortho-hydroxy derivatives of 2,5-diaryl-1,3oxazole. Activity of apoptosis signal-regulating kinase 1 and p...
By Anton Tkachenko, Dmytro Marakushyn, Iuliia Kalashnyk, Yevgen Korniyenko, Onishchenko Anatolii, Tatyana Gorbach, Oksana Nakonechna, Yevgen Posokhov, Alexander Tsygankov